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Proteomic insights into extracellular vesicles in ALS for therapeutic potential of Ropinirole and biomarker discovery
BackgroundExtracellular vesicles (EVs) hold the potential for elucidating the pathogenesis of amyotrophic lateral sclerosis (ALS) and serve as...
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Polycomb function in early mouse development
Epigenetic factors are crucial for ensuring proper chromatin dynamics during the initial stages of embryo development. Among these factors, the...
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PET Images Enhancement Using Deep Training of Reconstructed Images with Bayesian Penalized Likelihood Algorithm
PurposeTo adopt the merits of the Bayesian Penalized Likelihood (BPL) reconstruction algorithm (incl. improved contrast recovery), a deep learning...
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Vaginal irritation testing—prospects of human organotypic vaginal tissue culture models
Personal lubricants intended for local or systemic delivery via the vaginal route can induce vaginal irritation, damage the vaginal epithelial...
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The Goldilocks Dilemma: the optimal management strategy for invasive trees in the Atlantic Forest
This study addresses the broader issue of invasive species management, particularly within the context of highly biodiverse yet threatened ecosystems...
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YTH domain family protein 3 accelerates non-small cell lung cancer immune evasion through targeting CD8+ T lymphocytes
Immune evasion is one of the critical hallmarks of malignant tumors, especially non-small cell lung cancer (NSCLC). Emerging findings have...
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Dexmedetomidine and argon in combination against ferroptosis through tackling TXNIP-mediated oxidative stress in DCD porcine livers
Graft availability from donation after circulatory death (DCD) is significantly limited by ischaemia reperfusion (IR) injury. Effective strategies to...
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Fractal morphology of mechanosensory lateral-line canals in Stichaeidae
The marine teleost family Stichaeidae shows considerable variation in the morphology of mechanosensory lateral-line canals across its six...
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RNA scaffolds the Golgi ribbon by forming condensates with GM130
The mammalian Golgi is composed of stacks that are laterally connected into a continuous ribbon-like structure. The integrity and function of the...
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Exploring the osteogenic potential of semisynthetic triterpenes from Combretum leprosum: An in vitro and in silico study
Combretum leprosum Mart. is a plant of the Combretaceae family, widely distributed in the Northeast region of Brazil, popularly used as an...
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Investigating the impact of different routes of nano and micro nickel oxide administration on rat kidney architecture, apoptosis markers, oxidative stress, and histopathology
Although the production and use of nickel oxide nanoparticles (NiONP) are widespread, environmental and public health problems are associated with...
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Synthetic macrolides overcoming MLSBK-resistant pathogens
Conventional macrolide-lincosamide-streptogramin B-ketolide (MLS B K) antibiotics are unable to counter the growing challenge of antibiotic resistance...
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Advancing stroke recovery: unlocking the potential of cellular dynamics in stroke recovery
Stroke stands as a predominant cause of mortality and morbidity worldwide, and there is a pressing need for effective therapies to improve outcomes...
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Modified mesenchymal stromal cells by in vitro transcribed mRNA: a therapeutic strategy for hepatocellular carcinoma
BackgroundMesenchymal stromal cells (MSCs) tropism for tumours allows their use as carriers of antitumoural factors and in vitro transcribed mRNA...
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Noneffectiveness of cryostorage duration on clinical and neonatal outcomes after single vitrified-warmed blastocyst transfers
BackgroundIn the current era of assisted reproductive technology, the strategy of single vitrified-warmed blastocyst transfer (SVBT) is acknowledged...
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Dysregulated Wnt/β-catenin signaling confers resistance to cuproptosis in cancer cells
Cuproptosis is characterized by the aggregation of lipoylated enzymes of the tricarboxylic acid cycle and subsequent loss of iron-sulfur cluster...
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The evolving landscape of publishing in human reproduction: an analysis of scientometric data, open-access publishing, and article processing charges
BackgroundThis bibliometric study aims to examine the associations of journals in the field of human reproduction with their access types and article...
