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Diphtheria toxin, diphtheria-related fusion protein toxins, and the molecular mechanism of their action against eukaryotic cells
Diphtheria toxin remains one of the most successfully studied of the bacterial protein toxins. A detailed understanding of the structure function... -
Transfer RNA modifications and modifying enzymes in Saccharomyces cerevisiae
Transfer RNAs are adaptor molecules, which decode mRNA into protein and, thereby, play a central role in gene expression. During the maturation of a... -
The biosynthesis and functional roles of methylated nucleosides in eukaryotic mRNA
Modified nucleosides are present in mRNA of all eukaryotes, albeit at much lower levels than in other RNA moieties such as rRNA, tRNA, and snRNA.... -
New P-Chirogenic Phosphine Ligands and Their Use in Catalytic Asymmetric Reactions
This chapter is concerned with an update on the preparation and applications of optically active phosphine ligands which bear the chiral center at a... -
Liquid Chromatography under Critical and Limiting Conditions: A Survey of Experimental Systems for Synthetic Polymers
At the interface between the entropic size exclusion separation and the enthalpydominated liquid adsorption chromatography it is possible,... -
Liquid Sulfur
The molecular composition as well as the physical properties (including spectra) of liquid sulfur Liquid Sulfur... -
Laser Application of Polymers
Laser ablation of polymers has been studied with designed materials to evaluate the mechanism of ablation and the role of photochemically active... -
Speciation and Thermodynamics of Sulfur Vapor
Sulfur vapor Sulfur vapor at temperatures of between 200 and 1000 °C consists of all molecules with 2–10 atoms, some... -
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Spin Crossover in Iron(II) Tris(diimine) and Bis(terimine) Systems
Tris(diimine) and bis(terimine) iron(II) complex salts constitute one of the major classes of spin crossover systems. Both electronic and structural... -
Surface Modification of Polyethylene
Polyolefins such as polyethylene, polypropylene and their copolymers have excellent bulk physical/chemical properties, are... -
Dye-Based Organogels: Stimuli-Responsive Soft Materials Based on One-Dimensional Self-Assembling Aromatic Dyes
In this review, low molecular-weight organogel based on aromatic dye molecules and its stimuli-responsiveness were summarized. Aromatic dyes from... -
Lithium-Normalized Zinc and Copper Concentrations in Sediments as Measures of Trace Metal Enrichment due to Salmon Aquaculture
The results of metal analyses carried out on surficial sediment samples collected in the coastal waters of southwest New Brunswick and the... -
The Suitability of Electrode Measurements for Assessment of Benthic Organic Impact and Their use in a Management System for Marine Fish Farms
A management system for marine fish farms in Norway has recommended the use of simple electrode measurements of redox potentials (E... -
Model-based Inference of Gene Expression Dynamics from Sequence Information
A dynamic model of prokaryotic gene expression is developed that makes considerable use of gene sequence information. The main contribution arises... -
Plant Cells: Secondary Metabolite Heterogeneity and Its Manipulation
This chapter proposes the concept of rational manipulation of secondary metabolite heterogeneity in plant cell cultures. The heterogeneity of... -
Checkpoint and Coordinated Cellular Responses to DNA Damage
The DNA damage and replication checkpoints are signaling mechanisms that regulate and coordinate cellular responses to genotoxic conditions. The... -
New Phosphorylated Hosts for the Design of New Supramolecular Assemblies
Development of chemistry around new phosphorylated hosts provides an interesting new area of investigations in the design of host-guest systems.... -
Probing Hydrogen Bonding in Solids Using Solid State NMR Spectroscopy
Solid state nuclear magnetic resonance (NMR) spectroscopy is a powerful and versatile technique for probing structural and dynamic properties of... -
Bioprocess Monitoring Using Near-Infrared Spectroscopy
Near-infrared spectroscopy (NIR) is a nondestructive analytical technique that has been used for simultaneous prediction of the concentrations of...