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  1. From Genetic Variation to Probabilistic Modeling

    Genetic algorithms ⦓GAs) [53, 83] are stochastic optimization methods inspired by natural evolution and genetics. Over the last few decades, GAs have...
    Chapter
  2. Hierarchical Bayesian Optimization Algorithm

    The previous chapter has discussed how hierarchy can be used to reduce problem complexity in black-box optimization. Additionally, the chapter has...
    Chapter
  3. The Challenge of Hierarchical Difficulty

    Thus far, we have examined the Bayesian optimization algorithm (BOA), empirical results of its application to several problems of bounded difficulty,...
    Chapter
  4. Hierarchical BOA in the Real World

    The last chapter designed hBOA, which was shown to provide scalable solution for hierarchical traps. Since hierarchical traps were designed to test...
    Chapter
  5. Bayesian Optimization Algorithm

    The previous chapter argued that using probabilistic models with multivariate interactions is a powerful approach to solving problems of bounded...
    Chapter
  6. Probabilistic Model-Building Genetic Algorithms

    The previous chapter showed that variation operators in genetic and evolutionary algorithms can be replaced by learning a probabilistic model of...
    Chapter
  7. Scalability Analysis

    The empirical results of the last chapter were tantalizing. Easy and hard problems were automatically solved without user intervention in polynomial...
    Chapter
  8. Summary and Conclusions

    The purpose of this chapter is to provide a summary of main contributions of this work and outline important conclusions.
    Chapter
  9. A Mass-Conservative Reduced-Order Algorithm in Solving Optimal Control of Convection-Diffusion Equation

    This paper introduces a novel approach, the mass-conservative reduced-order characteristic finite element (MCROCFE) method, designed for optimal...

    Junpeng Song, Qiuqin Wu, Yi Shi in Journal of Scientific Computing
    Article 14 July 2024
  10. An innovative fourth-order numerical scheme with error analysis for Lane-Emden-Fowler type systems

    In this paper, we develop a novel higher-order compact finite difference scheme for solving systems of Lane-Emden-Fowler type equations. Our method...

    Nirupam Sahoo, Randhir Singh, Higinio Ramos in Numerical Algorithms
    Article 13 July 2024
  11. Enhancing SNV identification in whole-genome sequencing data through the incorporation of known genetic variants into the minimap2 index

    Motivation

    Alignment of reads to a reference genome sequence is one of the key steps in the analysis of human whole-genome sequencing data obtained...

    Guguchkin Egor, Kasianov Artem, ... Karpulevich Evgeny in BMC Bioinformatics
    Article Open access 13 July 2024
  12. Sublinear Algorithms in T-Interval Dynamic Networks

    We consider standard T - interval dynamic networks , under the synchronous timing model and the broadcast CONGEST model. In a T - interval dynamic network ,...

    Irvan Jahja, Haifeng Yu in Algorithmica
    Article 12 July 2024
  13. METASEED: a novel approach to full-length 16S rRNA gene reconstruction from short read data

    Background

    With the emergence of Oxford Nanopore technology, now the on-site sequencing of 16S rRNA from environments is available. Due to the error...

    Melcy Philip, Knut Rudi, ... Lars-Gustav Snipen in BMC Bioinformatics
    Article Open access 12 July 2024
  14. expHRD: an individualized, transcriptome-based prediction model for homologous recombination deficiency assessment in cancer

    Background

    Homologous recombination deficiency (HRD) stands as a clinical indicator for discerning responsive outcomes to platinum-based chemotherapy...

    Jae Jun Lee, Hyun Ju Kang, ... **ho Kim in BMC Bioinformatics
    Article Open access 12 July 2024
  15. Superconvergence Analysis of a Robust Orthogonal Gauss Collocation Method for 2D Fourth-Order Subdiffusion Equations

    In this paper, we study the orthogonal Gauss collocation method (OGCM) with an arbitrary polynomial degree for the numerical solution of a...

    Xuehua Yang, Zhimin Zhang in Journal of Scientific Computing
    Article 12 July 2024
  16. Unconditional energy stability and maximum principle preserving scheme for the Allen-Cahn equation

    In this paper, we propose a novel fully implicit numerical scheme that satisfies both nonlinear energy stability and maximum principle for the space...

    Zhuangzhi Xu, Yayun Fu in Numerical Algorithms
    Article 12 July 2024
  17. Building RadiologyNET: an unsupervised approach to annotating a large-scale multimodal medical database

    Background

    The use of machine learning in medical diagnosis and treatment has grown significantly in recent years with the development of...

    Mateja Napravnik, Franko Hržić, ... Ivan Štajduhar in BioData Mining
    Article Open access 12 July 2024
  18. Gradient-Based Monte Carlo Methods for Relaxation Approximations of Hyperbolic Conservation Laws

    Particle methods based on evolving the spatial derivatives of the solution were originally introduced to simulate reaction-diffusion processes,...

    Giulia Bertaglia, Lorenzo Pareschi, Russel E. Caflisch in Journal of Scientific Computing
    Article Open access 11 July 2024
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