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STED Imaging of Vesicular Endocytosis in the Synapse
Endocytosis is a fundamental biological process that couples exocytosis to maintain the homeostasis of the plasma membrane and sustained...
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Sublingual sufentanil for patient-controlled analgesia during labor induction for pregnancy termination: an effective and well-tolerated approach
BackgroundEffective pain management during labor induction for pregnancy termination is essential. However, to date, no effective treatment has been...
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Impact of non-emergency surgical timing on postoperative recovery quality in mild or asymptomatic SARS-CoV-2 infected patients: a grouped cohort study
ObjectiveTo explore the relationship between the timing of non-emergency surgery in mild or asymptomatic SARS-CoV-2 (severe acute respiratory...
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Perfusion deficits may underlie lung and kidney injury in severe COVID-19 disease: insights from a multicenter international cohort study
BackgroundLung perfusion defects, mainly due to endothelial and coagulation activation, are a key contributor to COVID-19 respiratory failure....
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Comparison of remimazolam tosilate and propofol during induction and maintenance of general anesthesia in patients undergoing laparoscopic cholecystectomy: a prospective, single center, randomized controlled trial
BackgroundRemimazolam tosilate (RT) is a new, ultrashort-acting benzodiazepine. Here, we investigated the efficacy and safety of RT for general...
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Real-time analgesic efficacy and factors determining drug requirements of combined spinal-epidural analgesia for labor: a prospective cohort study
PurposeCombined spinal-epidural analgesia (CSEA) is effective but not sufficient for labor pain. This study was conducted to assess the real-time...
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The impact of intraoperative hypotension on postoperative acute kidney injury, mortality and length of stay following off-pump coronary artery bypass grafting surgery: a single-center retrospective cohort study
BackgroundOff-pump coronary artery bypass grafting (OPCABG) presents distinct hemodynamic characteristics, yet the relationship between...
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Breathlessness assessment, management and impact in the intensive care unit: a rapid review and narrative synthesis
BackgroundAdults in the intensive care unit (ICU) commonly experience distressing symptoms and other concerns such as pain, delirium, and...
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The use of Guyton’s approach to the control of cardiac output for clinical fluid management
Infusion of fluids is one of the most common medical acts when resuscitating critically ill patients. However, fluids most often are given without...
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Quantitative and calculated estimated blood loss in cesarean deliveries for twin and singleton pregnancies: a retrospective analysis
PurposeThis study retrospectively assessed blood loss during cesarean deliveries for twin and singleton pregnancies using two distinct methods,...
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Recruitment-to-inflation ratio reflects the impact of peep on dynamic lung strain in a highly recruitable model of ARDS
BackgroundThe recruitment-to-inflation ratio (R/I) has been recently proposed to bedside assess response to PEEP. The impact of PEEP on...
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Criteria for stop** high-flow nasal oxygen for acute hypoxemic respiratory failure: a systematic review of randomized controlled trials
High-flow nasal cannula (HFNC) has been widely promoted during the COVID-19 pandemic to circumvent invasive mechanical ventilation. While there are...
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Construction and validation of a risk prediction model for postoperative ICU admission in patients with colorectal cancer: clinical prediction model study
BackgroundTransfer to the ICU is common following non-cardiac surgeries, including radical colorectal cancer (CRC) resection. Understanding the...
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Comparison of different concentrations of ropivacaine in epidural anesthesia for percutaneous transforaminal endoscopic discectomy: a randomized controlled trial
BackgroundThis study investigated the optimal concentration of ropivacaine epidural anesthesia for clinical use in percutaneous transforaminal...
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Inferior vena cava ultrasound to predict hypotension after general anesthesia induction: a systematic review and meta-analysis of observational studies
PurposeHypotension after induction of general anesthesia is common and is associated with significant adverse events. Identification of patients at...
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Upper gastrointestinal bleeding on veno-arterial extracorporeal membrane oxygenation support
IntroductionPatients on veno-arterial extracorporeal membrane oxygenation (V-A ECMO) support are at a high risk of hemorrhagic complications,...
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Accuracy of oscillometric noninvasive blood pressure at the ankle in the lateral position during general anesthesia
BackgroundThis study aimed to evaluate the accuracy of ankle blood pressure measurements in relation to invasive blood pressure in the lateral...
