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miR-520a-5p regulates Frizzled 9 expression and mediates effects of cigarette smoke and iloprost chemoprevention
Expression of Frizzled 9 (FZD9) is critical to the activity of the lung cancer chemoprevention agent and prostacyclin analogue, iloprost. FZD9 is...
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NUMB suppression by miR-9-5P enhances CD44+ prostate cancer stem cell growth and metastasis
Experimental and clinical studies over the past two decades have provided overwhelming evidence that human cancers, including prostate cancer (PCa),...
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EGF-mediated reduced miR-92a-1-5p controls HTR-8/SVneo cell invasion through activation of MAPK8 and FAS which in turn increase MMP-2/-9 expression
The members of human miR-17-92 cluster are implicated in several cancers and are known to increase cancer cells invasiveness. The present study...
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Inducible deletion of microRNA activity in kidney mesenchymal cells exacerbates renal fibrosis
MicroRNAs (miRNAs) are sequence-specific inhibitors of post-transcriptional gene expression. However, the physiological functions of these non-coding...
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Hypoxia treatment and resistance training alters microRNA profiling in rats skeletal muscle
MicroRNAs (miRNAs) may play a crucial regulatory role in the process of muscle atrophy induced by high-altitude hypoxia and its amelioration through...
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Longitudinal dynamics of circulating miRNAs in a swine model of familial hypercholesterolemia during early atherosclerosis
Atherosclerosis is a complex progressive disease involving intertwined biological mechanisms. We aimed to identify miRNA expression dynamics at the...
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Differential expression of aqueous humor microRNAs in central retinal vein occlusion and its association with matrix metalloproteinases: a pilot study
The aim of this study is to investigate the differential expression of microRNAs (miRNAs) in the aqueous humor (AH) of patients with central retinal...
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Identification of microRNAs associated with human fragile X syndrome using next-generation sequencing
Fragile X syndrome (FXS) is caused by a mutation in the FMR1 gene which can lead to a loss or shortage of the FMR1 protein. This protein interacts...
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MiR-26a-5p as a useful therapeutic target for upper tract urothelial carcinoma by regulating WNT5A/β-catenin signaling
The role of miRNAs in cancer and their possible function as therapeutic agents are interesting and needed further investigation. The miR-26a-5p had...
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Circulating miRNA expression in long-standing type 1 diabetes mellitus
Type 1 diabetes is a chronic autoimmune disease which results in inefficient regulation of glucose homeostasis and can lead to different vascular...
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A circulating microRNA panel as a novel dynamic monitor for oral squamous cell carcinoma
Oral squamous cell carcinoma (OSCC) has high recurrence and mortality rates despite advances in diagnosis and treatment. Therefore, it is necessary...
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Identification of novel candidate genes and predicted miRNAs in atopic dermatitis patients by bioinformatic methods
Atopic dermatitis (AD) is a common, chronic inflammatory dermatosis with relapsing eruptions. Our study used bioinformatics to find novel candidate...
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Systematic analysis identifies REST as an oncogenic and immunological biomarker in glioma
The repressor element 1 silencing transcription factor (REST) has been proposed to function as a transcription factor to silence gene transcription...
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Large-scale analysis of MicroRNA expression in motor neuron-like cells derived from human umbilical cord blood mesenchymal stem cells
Motor neuron diseases such as spinal cord injuries and amyotrophic lateral sclerosis are known as the most common disorders worldwide. Using stem...
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Evaluation of endogenous miRNA reference genes across different zebrafish strains, developmental stages and kidney disease models
The majority of kidney diseases arise from the loss of podocytes and from morphological changes of their highly complex foot process architecture,...
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Transcriptomic and glycomic analyses highlight pathway-specific glycosylation alterations unique to Alzheimer’s disease
Glycosylation has been found to be altered in the brains of individuals with Alzheimer’s disease (AD). However, it is unknown which specific...
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Identifying differentially expressed genes and miRNAs in Kawasaki disease by bioinformatics analysis
Kawasaki disease (KD) is an acute systemic immune vasculitis caused by infection, and its etiology and underlying mechanisms are not completely...
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Protective role of ABCA1 in ischemic preconditioning is mediated by downregulation of miR-33-5p and miR-135-5p
Ischemic preconditioning (IPC) significantly reduces ischemia–reperfusion injury in the brain by inducing ischemic tolerance. Although emerging...
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Urinary microRNA biomarkers for detecting the presence of esophageal cancer
Esophageal cancer (EC) including esophageal squamous cell carcinoma (ESCC) and adenocarcinoma (EAC) generally exhibits poor prognosis; hence, a...
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RETRACTED ARTICLE: Integrative analysis of the circRNA–miRNA regulatory network in atrial fibrillation
We aimed to investigate the circRNA–miRNA regulatory network in atrial fibrillation (AF) by using Cytoscape and HMDD v3.0. Finally, 120...
