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Proteomic profiling of regenerated urinary bladder tissue in a non-human primate augmentation model
Urinary bladder dysfunction can be caused by environmental, genetic, and developmental insults. Depending upon insult severity, the bladder may lose...
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Elastic porous microspheres/extracellular matrix hydrogel injectable composites releasing dual bio-factors enable tissue regeneration
Injectable biomaterials have garnered increasing attention for their potential and beneficial applications in minimally invasive surgical procedures...
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The effects of bone marrow stem and progenitor cell seeding on urinary bladder tissue regeneration
Complications associated with urinary bladder augmentation provide the motivation to delineate alternative bladder tissue regenerative engineering...
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Telocytes and ezrin expression in normal-appearing tissues adjacent to urothelial bladder carcinoma as predictors of invasiveness and recurrence
Recurrence and progression rates vary widely among different histological subtypes of bladder cancer (BC). Normal-appearing mucosa in non-muscle...
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Creation of bladder assembloids mimicking tissue regeneration and cancer
Current organoid models are limited by their inability to mimic mature organ architecture and associated tissue microenvironments
1 ,2 . Here we create...
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Spinal cord repair is modulated by the neurogenic factor Hb-egf under direction of a regeneration-associated enhancer
Unlike adult mammals, zebrafish regenerate spinal cord tissue and recover locomotor ability after a paralyzing injury. Here, we find that ependymal...
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Circulating exosomal miR-16-5p and let-7e-5p are associated with bladder fibrosis of diabetic cystopathy
Diabetic cystopathy (DCP) is a prevalent etiology of bladder dysfunction in individuals with longstanding diabetes, frequently leading to bladder...
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Laparoscopic ureteroneocystostomy with bladder flap for benign ureteral stenosis: our initial experience
To present our experience with laparoscopic ureteroneocystostomy with bladder flap (LUCBF) for treating benign ureteral stenosis and evaluate its...
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Small leucine-rich proteoglycans inhibit CNS regeneration by modifying the structural and mechanical properties of the lesion environment
Extracellular matrix (ECM) deposition after central nervous system (CNS) injury leads to inhibitory scarring in humans and other mammals, whereas it...
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Low-energy shock wave therapy ameliorates ischemic-induced overactive bladder in a rat model
This study was to evaluate whether Low-energy shock wave therapy (LESW) improves ischemic-induced overactive bladder in rats and investigate its...
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Safety and tissue remodeling assay of small intestinal submucosa meshes using a modified porcine surgical hernia model
In studies to date, meshes based on extracellular matrix (ECM) have been extensively used in clinical applications. Unfortunately, little is known...
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Bile proteome reveals biliary regeneration during normothermic preservation of human donor livers
Normothermic machine perfusion (NMP) after static cold storage is increasingly used for preservation and assessment of human donor livers prior to...
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Pparg signaling controls bladder cancer subtype and immune exclusion
Pparg , a nuclear receptor, is downregulated in basal subtype bladder cancers that tend to be muscle invasive and amplified in luminal subtype bladder...
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Advancing autologous urothelial micrografting and composite tubular grafts for future single-staged urogenital reconstructions
Urogenital reconstructive surgery can be impeded by lack of tissue. Further developments within the discipline of tissue engineering may be part of a...
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Calcination and ion substitution improve physicochemical and biological properties of nanohydroxyapatite for bone tissue engineering applications
Nanohydroxyapatite (nanoHAP) is widely used in bone regeneration, but there is a need to enhance its properties to provide stimuli for cell...
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mRNA–miRNA bipartite networks reconstruction in different tissues of bladder cancer based on gene co-expression network analysis
Bladder cancer (BC) is one of the most important cancers worldwide, and if it is diagnosed early, its progression in humans can be prevented and...
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Recellularized lymph node scaffolds with human adipose-derived stem cells enhance lymph node regeneration to improve lymphedema
To overcome the limitations of lymphedema treatment, human adipose-derived stem cells (hADSCs) were injected into decellularized lymph nodes to...
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Development of a conductive biocomposite combining graphene and amniotic membrane for replacement of the neuronal network of tissue-engineered urinary bladder
Tissue engineering allows to combine biomaterials and seeded cells to experimentally replace urinary bladder wall. The normal bladder wall however,...
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A new heterotropic vascularized model of total urinary bladder transplantation in a rat model
This study developed a new procedure of urinary bladder transplantation on a rat model (n = 40). Heterotopic urinary bladder transplantation (n = 10)...
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Obesity-associated microbiomes instigate visceral adipose tissue inflammation by recruitment of distinct neutrophils
Neutrophils are increasingly implicated in chronic inflammation and metabolic disorders. Here, we show that visceral adipose tissue (VAT) from...
