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Diet changes due to urbanization in South Africa are linked to microbiome and metabolome signatures of Westernization and colorectal cancer
Transition from traditional high-fiber to Western diets in urbanizing communities of Sub-Saharan Africa is associated with increased risk of...
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Effect of diet supplemented with functional amino acids and polyphenols on gut health in broilers subjected to a corticosterone-induced stress
To address the overuse of antimicrobials in poultry production, new functional feed ingredients, i.e. ingredients with benefits beyond meeting basic...
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Alterations in skeletal muscle morphology and mechanics in juvenile male Sprague Dawley rats exposed to a high-fat high-sucrose diet
Although once a health concern largely considered in adults, the obesity epidemic is now prevalent in pediatric populations. While detrimental...
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The role of high fat diet on serum uric acid level among healthy male first degree relatives of type 2 diabetes mellitus
First-degree relatives (FDR) of type 2 diabetes mellitus have increased risk of develo** insulin resistance-related disorders including...
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Diet replacement with whole insect larvae affects intestinal morphology and microbiota of broiler chickens
Insect-based diets are gaining interest as potential ingredients in improving poultry gut health. This study assessed the dietary treatment with...
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Replacement of saturated fatty acids with linoleic acid in western diet attenuates atherosclerosis in a mouse model with inducible ablation of hepatic LDL receptor
Dietary saturate fatty acids (SFAs) have been consistently linked to atherosclerosis and obesity, both of which are characterized by chronic...
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Innovative high fat diet establishes a novel zebrafish model for the study of visceral obesity
Obesity is a complex chronic condition associated with multiple health risks, including visceral obesity, which is particularly detrimental. To gain...
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Intermittent fasting activates macrophage migration inhibitory factor and alleviates high-fat diet-induced nonalcoholic fatty liver disease
Switching to normal diet (ND) is the regular therapy for high-fat diet (HFD)-induced nonalcoholic fatty liver disease (NAFLD). Intermittent fasting...
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High-fat diet causes mechanical allodynia in the absence of injury or diabetic pathology
Understanding the interactions between diet, obesity, and diabetes is important to tease out mechanisms in painful pathology. Western diet is rich in...
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Maternal diet induces persistent DNA methylation changes in the muscle of beef calves
Maternal nutrition during pregnancy can induce epigenetic alterations in the fetal genome, such as changes in DNA methylation. It remains unclear...
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A high-cholesterol diet promotes the intravasation of breast tumor cells through an LDL–LDLR axis
Most metastases in breast cancer occur via the dissemination of tumor cells through the bloodstream. How tumor cells enter the blood (intravasation)...
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Effect of providing citrus pulp-integrated diet on fecal microbiota and serum and fecal metabolome shifts in crossbred pigs
The study aimed to assess the impact of dehydrated citrus pulp (DCP) on growth performance, fecal characteristics, fecal bacterial composition (based...
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Consumption of interesterified palm oil leads inflammation of white adipose tissue and triggers metabolic disturbances in mice on a high-fat diet
Growing obesity is linked to shifts in dietary patterns, particularly the increased intake of ultra-processed high-fat foods. This study aimed to...
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Protective effects of niacin following high fat rich diet: an in-vivo and in-silico study
Niacin had long been understood as an antioxidant. There were reports that high fat diet (HFD) may cause psychological and physical impairments. The...
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A novel hepatocyte ketone production assay to help the selection of nutrients for the ketogenic diet treatment of epilepsy
The classic ketogenic diet is an effective treatment option for drug-resistant epilepsy, but its high fat content challenges patient compliance....
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Amoxicillin impact on pathophysiology induced by short term high salt diet in mice
Current evidence emerging from both human and animal models confirms that high-salt diet consumption over a period modulates the gut ecology and...
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Partially defatted rather than native poppy seeds beneficially alter lipid metabolism in rats fed a high-fat diet
Partially defatted poppy seeds, a by-product of poppy oil cold pressing, could be an interesting dietary supplement for obesity management. The aim...
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Impact of diet on human nutrition, immune response, gut microbiome, and cognition in an isolated and confined mission environment
Long-duration spaceflight impacts human physiology, including well documented immune system dysregulation. The space food system has the potential to...
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Blood phenylalanine fluctuation in phenylketonuric children treated by BH4 or low-phenylalanine diet from birth
The prognosis of phenylketonuria (PKU) is related to the quality of metabolic control all life-long. PKU treatment is based on a low-Phe diet,...
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Fasting mimicking diet in mice delays cancer growth and reduces immunotherapy-associated cardiovascular and systemic side effects
Immune checkpoint inhibitors cause side effects ranging from autoimmune endocrine disorders to severe cardiotoxicity. Periodic Fasting mimicking diet...
