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T-cell specific antibody induction versus corticosteroid induction immunosuppression for liver transplant recipients: a meta-analysis
Corticosteroids remain the mainstay of immunosuppression for liver transplant recipients despite several serious complications including infection,...
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Prognostic tools and candidate drugs based on plasma proteomics of patients with severe COVID-19 complications
COVID-19 complications still present a huge burden on healthcare systems and warrant predictive risk models to triage patients and inform early...
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Characterizing the differences between multisystem inflammatory syndrome in children and Kawasaki disease
To characterize the new SARS-Co-V-2 related multisystem inflammatory syndrome in children (MIS-C) among Israeli children and to compare it with...
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Effectiveness of a computerized clinical decision support system for prevention of glucocorticoid-induced osteoporosis
Glucocorticoids are widely used for a variety of diseases, but the prevention of glucocorticoid-induced osteoporosis is sometimes neglected....
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Blood perfusion with polymyxin B immobilized columns in patients with COVID-19 requiring oxygen therapy
Extracorporeal blood purification with polymyxin B immobilized fiber column direct hemoperfusion (PMX-DHP), is reported to be effective in treating...
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Impact of the revised definition on incidence and outcomes of acute exacerbation of idiopathic pulmonary fibrosis
The revised definition of acute exacerbation (AE) in idiopathic pulmonary fibrosis (IPF) was proposed in 2016, but changes in the incidence and...
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High-dose extended-field radiotherapy plus chemotherapy improved survival in extranodal NK/T-cell lymphoma in a real-life setting: results from the multicenter T-Cell Brazil Project
Extranodal natural-killer/T-cell lymphoma (ENKTL) is a rare and aggressive Epstein-Barr virus related mature T-cell and natural-killer malignancy....
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Distinct pulmonary and systemic effects of dexamethasone in severe COVID-19
Dexamethasone is the standard of care for critically ill patients with COVID-19, but the mechanisms by which it decreases mortality and its...
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CYP3A-status is associated with blood concentration and dose-requirement of tacrolimus in heart transplant recipients
High inter-individual variability in tacrolimus clearance is attributed to genetic polymorphisms of CYP3A enzymes. However, due to CYP3A...
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Early dexamethasone use as a protective measure in non-mechanically ventilated critically ill patients with COVID-19: a multicenter, cohort study
Dexamethasone showed mortality benefits in patients with COVID-19. However, the optimal timing for dexamethasone initiation to prevent COVID-19...
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Elevated serum levels of bone morphogenetic protein-9 are associated with better outcome in AQP4-IgG seropositive NMOSD
Lymphatic drainage in the central nervous system is regulated by meningeal lymphatic vasculature, and recurrent neuroinflammation alters lymphatic...
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CASPR2 antibody associated neurological syndromes in children
To strengthen the understanding of the clinical features for CASPR2 neurological autoimmunity in children. A multicenter retrospective and...
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Prognostic factors of restrictive myopathy in thyroid eye disease
To investigate the prognostic factors of extraocular muscle restriction in patients with thyroid eye disease (TED), 65 patients with TED and...
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Lrig1-expression confers suppressive function to CD4+ cells and is essential for averting autoimmunity via the Smad2/3/Foxp3 axis
Regulatory T cells (T reg ) are CD4 + T cells with immune-suppressive function, which is defined by Foxp3 expression. However, the molecular...
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CANVAS-related RFC1 mutations in patients with immune-mediated neuropathy
Cerebellar ataxia, neuropathy, and vestibular areflexia syndrome (CANVAS) has recently been attributed to biallelic repeat expansions in RFC1 . More...
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Survival after partial heart transplantation in a piglet model
Partial heart transplantation (PHT) is a novel surgical approach that involves transplantation of only the part of the heart containing a valve. The...
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Stem cell transplant for mantle cell lymphoma in Taiwan
Mantle cell lymphoma (MCL) is a B-cell lymphoma featuring an aggressive course and a progressive relapsing pattern. International guidelines...
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Increased renal function decline in fast metabolizers using extended-release tacrolimus after kidney transplantation
Fast metabolism of immediate-release tacrolimus (IR-Tac) is associated with decreased kidney function after renal transplantation (RTx) compared to...
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Comparison of the effect of Everolimus, Prednisolone, and a combination of both on experimentally induced peritoneal adhesions in rats
Postoperative intra-abdominal adhesions represent a significant post-surgical problem. Its complications can cause a considerable clinical and cost...
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Clinico-radiologic subtypes and therapeutic observation of acute Marchiafava-Bignami disease
We aimed to investigate the clinico-radiologic features of acute Marchiafava-Bignami disease (MBD) and its evolutionary process after effective...
