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Chemotherapy-induced peripheral neuropathy—part 2: focus on the prevention of oxaliplatin-induced neurotoxicity
BackgroundChemotherapy-induced peripheral neuropathy (CIPN) is regarded as one of the most common dose-limiting adverse effects of several...
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Understanding of sarcopenia: from definition to therapeutic strategies
Sarcopenia refers to the gradual loss of skeletal muscle mass and function along with aging and is a social burden due to growing healthcare cost...
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Lipoteichoic acids as a major virulence factor causing inflammatory responses via Toll-like receptor 2
Lipoteichoic acid (LTA), a major cell wall component of Gram-positive bacteria, is associated with various inflammatory diseases ranging from minor...
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Toll-like receptors: promising therapeutic targets for inflammatory diseases
The health of living organisms is constantly challenged by bacterial and viral threats. The recognition of pathogenic microorganisms by diverse...
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Telmisartan attenuates diabetes induced depression in rats
BackgroundRole of brain renin angiotensin system (RAS) is well understood and various clinical studies have proposed neuroprotective effects of...
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Flavonoids as Potential Immunosuppressants Affecting Intracellular Signaling Pathways (a Review)
Flavonoids are a large group of polyphenolic compounds that are present in almost all higher plants. Recent research demonstrated a wide range of...
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Effect of para halogen modification of S-3-(phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamides on metabolism and clearance
The purpose of this study was to better understand why para -halogen modifications of S -3-(4-halophenoxy)-2-hydroxy-2-methyl- N -(4-nitro-3-trifluorometh...
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Roles of toll-like receptors in Cancer: A double-edged sword for defense and offense
Toll-like receptors (TLRs) belong to a class of pattern-recognition receptors that play an important role in host defense against pathogens by...
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Análisis de coste-efectividad del tratamiento empírico antimicrobiano de pacientes con neumonía asociada a la ventilación mecánica en unidades de cuidados intensivos del Instituto Mexicano del Seguro Social
Objective: Identify the most cost-effective antibiotic therapy (vancomycin vs imipenem, teicoplanin and linezolid) for the treatment of mechanic...
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Drugs targeting toll-like receptors
Animals and plants are exposed to myriads of potential microbial invaders. In case of animals, Toll-like receptors (TLRs) act as the primary defense...
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Coste-efectividad del tratamiento empírico de la neumonía nosocomial por Staphylococcus aureus resistente a meticilina con linezolid y vancomicina
Objectives: Linezolid has proved efficient in the treatment of meticillin-resistant Staphylococcus aureus (MRSA) infections, including nosocomial... -
Male Hypogonadism
Male hypogonadism is one of the most common endocrinologic syndromes. The diagnosis is based on clinical signs and symptoms plus laboratory...
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