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Cystine/glutamate antiporter System xc- deficiency impairs insulin secretion in mice
Aims/hypothesisGlutamate-induced cytotoxicity (excitotoxicity) has been detected in pancreatic beta cells. The cystine/glutamate antiporter System x c
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Newspaper Coverage and Framing of Bats, and Their Impact on Readership Engagement
The media is a valuable pathway for transforming people’s attitudes towards conservation issues. Understanding how bats are framed in the media is...
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Blood oxygen regulation via P2Y12R expressed in the carotid body
BackgroundPeripheral blood oxygen monitoring via chemoreceptors in the carotid body (CB) is an integral function of the autonomic cardiorespiratory...
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Release of endogenous dynorphin opioids in the prefrontal cortex disrupts cognition
Following repeated opioid use, some dependent individuals experience persistent cognitive deficits that contribute to relapse of drug-taking...
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Étude de l’activité antidiabétique de Capparis spinosa L. et de Calamintha officinalis Moench chez la souris diabétique
The anti-diabetic activities of Capparis spinosa (Cs) and Calamintha officinalis Moench (Co) were investigated in a diabetes mellitus model of mouse...
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Update on the Application of Monoclonal Antibody Therapy in Primary Membranous Nephropathy
When first introduced, rituximab (RTX), a chimeric anti-CD20 monoclonal antibody, brought about an alternative therapeutic paradigm for primary...
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Public perceptions of Lyme disease and climate change in southern Manitoba, Canada: making a case for strategic decoupling of climate and health messages
BackgroundDespite scientific evidence that climate change has profound and far reaching implications for public health, translating this knowledge in...
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Le rôle des modèles murins en immuno-oncologie
Preclinical models in oncology are generally used to test hypotheses generated through basic science. Thus, experiments on murine models are carried...
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Biomineralization Precursor Carrier System Based on Carboxyl-Functionalized Large Pore Mesoporous Silica Nanoparticles
Bone and teeth are derived from intrafibrillarly mineralized collagen fibrils as the second level of hierarchy. According to polymer-induced...
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Chauves-souris et virus : des relations complexes
With more than 1 200 species, bats and flying foxes (Order Chiroptera) constitute the most important and diverse order of Mammals after Rodents. Many...
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Un lien entre normalisation de l’angiogenèse et stimulation de l’immunité antitumorale
The ultimate goal of using anti-angiogenics for treating cancer is inhibiting angiogenesis and therefore blocking metastatic dissemination. However,...
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Does the edge effect impact on the measure of spatial accessibility to healthcare providers?
BackgroundSpatial accessibility indices are increasingly applied when investigating inequalities in health. Although most studies are making mentions...
