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Histopathological Features of Pendred Syndrome Thyroids Align with Differences in the Expression of Thyroid-Specific Markers, Apical Iodide Transporters, and Ciliogenesis Process
Pendred syndrome (PDS) is an autosomal recessive disorder caused by mutations in the gene that encodes pendrin. Pendred thyroid tissue is supposedly...
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Superb microvascular imaging (SMI) and elastosonography in thyroid nodule: diagnostic value in a real-time cohort
PurposeIn clinical practice, thyroid nodules are classified according to TI-RADS by B-mode and color-flow Doppler study. The aim of the study is to...
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Can sonographic features of microcalcification predict thyroid nodule malignancy? a prospective observational study
BackgroundThe aim of this study was to investigate the diagnostic accuracy of microcalcification, as well as its associated sonographic features, for...
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Robotic transaxillary thyroidectomy: time to expand indications?
In 2016, the American Thyroid Association published a statement on remote-access thyroid surgery claiming that it should be reserved to patients with...
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Multifocal Fibrosing Thyroiditis: an Under-recognized Mimicker of Papillary Thyroid Carcinoma
Multifocal fibrosing thyroiditis (MFT) is an enigmatic entity, characterized by multiple fibrotic scar-like lesions with a paucicellular fibrotic...
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Assessment of Accuracy of Fine Needle Aspiration Cytology and Ultrasonography in Relation to Histopathology in Cases of Solitary Thyroid Nodule
The thyroid gland is an endocrine gland situated in the lower part of front and the sides of the neck. Thyroid nodules are very common with estimated...
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Incidence of thyroid nodules in early stage autosomal polycystic kidney disease
BackgroundAutosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disease. Defect in cilia-mediated signaling...
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Analytical validation of a novel targeted next-generation sequencing assay for mutation detection in thyroid nodule aspirates and tissue
PurposeThe identification of somatic mutations in cancer specimens enables detection of molecular markers for personalized treatment. We recently...
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Identification of BRAF, CCND1, and MYC mutations in a patient with multiple primary malignant tumors: a case report and review of the literature
BackgroundMultiple primary malignant tumors (MPMTs), usually associated with worse malignant behavior and prognosis comparing to a single primary...
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Somatostatin receptor imaging of thyroid tissue and differentiated thyroid cancer using gallium-68-labeled radiotracers—a review of clinical studies
IntroductionThe rise in thyroid cancer incidence, especially papillary thyroid cancer (PTC), has underscored the need for improved diagnostic methods...
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The Thyroid Pathologist Meets Therapeutic Pharmacology
The effects of many pharmacological agents on thyroid function are well known. Direct influences on measurements of thyroid function tests are also...
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Transfer learning for automatic joint segmentation of thyroid and breast lesions from ultrasound images
P urposeIt plays a significant role to accurately and automatically segment lesions from ultrasound (US) images in clinical application. Nevertheless,...
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Towards in vivo characterization of thyroid nodules suspicious for malignancy using multispectral optoacoustic tomography
PurposePatient-tailored management of thyroid nodules requires improved risk of malignancy stratification by accurate preoperative nodule assessment,...
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‘Lateral Aberrant Thyroid Carcinoma’ or ‘Thyroglossal Duct Cyst Carcinoma Metastasizing to Neck Node’: Can we Decide in this Interesting Case Report?
Lateral aberrant thyroid(LAT) belongs to subset of ectopic thyroid, mostly presenting as asymptomatic lateral neck swelling and are challenging to...
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Insights Obtained from the Nontumorous Glandular Tissue in Patients with Endocrine Tumors
The pathology of neoplasia tends to focus on the tumor that requires characterization, grading, and staging. However, nontumorous tissue surrounding...
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Upregulation of dendrocyte-expressed seven transmembrane protein is associated with unfavorable outcomes in differentiated thyroid cancer
PurposeDendritic cell infiltrates are increased in thyroid cancer but may have a defective ability to provoke effective immune responses. In this...
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Ultrasound characteristics of normal parathyroid glands and analysis of the factors affecting their display
BackgroundParathyroid glands are important endocrine glands, and the identification of normal parathyroid glands is crucial for their protection. The...
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An unusual tracheal foreign body in a middle-aged male with a 15-year history of coal use: a case report
BackgroundLong-term exposure to coal dust causes respiratory disease. In chest computer tomography (CT), pulmonary nodules, pulmonary interstitial...
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Quantitative analysis of 99mTc-pertechnetate thyroid uptake with a large-field CZT gamma camera: feasibility and comparison between SPECT/CT and planar acquisitions
PurposeThe main objective of this study was to evaluate the ability of a large field Cadmium Zinc Telluride (CZT) camera to estimate thyroid uptake...
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Ultrasound determination of pediatric thyroid mass
BackgroundRadioiodine therapy for Graves disease can be achieved with dosing based on estimated thyroid gland mass. Thyroid mass can be estimated...