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Nanotechnology in leukemia: diagnosis, efficient-targeted drug delivery, and clinical trials
Leukemia is a group of malignant disorders which affect the blood and blood-forming tissues in the bone marrow, lymphatic system, and spleen. Many...
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Scaffolds: a biomaterial engineering in targeted drug delivery for osteoporosis
Osteoporosis is an increasingly common condition that causes low bone density, porous bone, and increased fracture risk. Treatments for osteoporosis...
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Niosomes: a novel targeted drug delivery system for cancer
Recently, nanotechnology is involved in various fields of science, of which medicine is one of the most obvious. The use of nanoparticles in the...
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Nanoengineered approaches to improve the efficacy of targeted drug delivery for the treatment of malignancy: a comprehensive review
BackgroundThe second leading cause of mortality in the world, behind cardiovascular disorders, is cancer. The currently employed treatment options...
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The blood–brain barrier: structure, regulation, and drug delivery
Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous system (CNS) from toxins and pathogens in blood. However,...
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Nano-Drug Carriers for Targeted Therapeutic Approaches in Oral Cancer: A Systematic Review
IntroductionNanotechnology has shown potential in treating different types of cancers. In particular, nano-drug delivery systems (DDSs) offer a...
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Emulsomes: new lipidic carriers for drug delivery with special mention to brain drug transport
BackgroundEmulsomes are a type of lipid-based nanoparticle that consists of a solid lipid core surrounded by a phospholipid bilayer and have shown...
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Immune cells: potential carriers or agents for drug delivery to the central nervous system
Drug delivery systems (DDS) have recently emerged as a promising approach for the unique advantages of drug protection and targeted delivery....
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Recent advancement of nanomedicine-based targeted delivery for cervical cancer treatment
Cervical cancer is a huge worldwide health burden, impacting women in impoverished nations in particular. Traditional therapeutic approaches, such as...
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Targeted delivery of liposomal Ribociclib to SLC7A5 transporters in breast cancer cells
This study aimed to prepare SLC7A5 transporters targeted liposomes of Ribociclib (RB) by stear(o)yl conjugation of Phe, Asp, Glu amino acids to...
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Preferences of Patients with Amyotrophic Lateral Sclerosis for Intrathecal Drug Delivery: Choosing between an Implanted Drug-Delivery Device and Therapeutic Lumbar Puncture
BackgroundNovel intrathecal treatments for amyotrophic lateral sclerosis (ALS) may require delivery using lumbar puncture (LP). Implanted...
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Sustained-release drug delivery systems
The design and development of a sustained-release drug delivery system targeting the administration of active pharmaceutical ingredients (APIs) to...
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Strategies to Improve Drug Delivery Across the Blood–Brain Barrier for Glioblastoma
Purpose of ReviewGlioblastoma remains resistant to most conventional treatments. Despite scientific advances in the past three decades, there has...
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Multifaceted applications of micro/nanorobots in pharmaceutical drug delivery systems: a comprehensive review
BackgroundDrug delivery systems (DDSs) encompass a wide range of methods, including oral, injectable, and topical routes of administration, all...
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Intrathecal Pump Drug Delivery
This book is a comprehensive guide to Targeted Drug Delivery (TDD), also known as Intrathecal Drug Delivery (IDD), and offers an overview to this... -
siRNA and targeted delivery systems in breast cancer therapy
Recently, nucleic acid drugs have been considered as promising candidates in treatment of various diseases, especially cancer. Because of develo**...
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Extracellular vesicle-mediated drug delivery in breast cancer theranostics
Breast cancer (BC) continues to be a significant global challenge due to drug resistance and severe side effects. The increasing prevalence is...
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Ionizable drug delivery systems for efficient and selective gene therapy
Gene therapy has shown great potential to treat various diseases by repairing the abnormal gene function. However, a great challenge in bringing the...
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Alzheimer’s disease and drug delivery across the blood–brain barrier: approaches and challenges
Alzheimer's disease (AD) is a diverse disease with a complex pathophysiology. The presence of extracellular β-amyloid deposition as neuritic plaques...
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Malaria Therapeutic Paradigm: An Evolution Towards Commercial Drug Delivery Technology
PurposeMalaria and other parasitic infections pose serious health risks to millions of people worldwide each year. Oral medication is a crucial...