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Development and validation of a neoadjuvant chemotherapy pathological complete remission model based on Reg IV expression in breast cancer tissues: a clinical retrospective study
ObjectiveTo develop and authenticate a neoadjuvant chemotherapy (NACT) pathological complete remission (pCR) model based on the expression of Reg IV...
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CDX2 and Reg IV expression and correlation in gastric cancer
BackgroundEctopic expression of CDX2 is associated with the development and progression of gastric cancer. Previous studies showed that CDX2 may be...
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KI basierter Rapid Evidence Generator mit risikoadjustiertem Propensity Score Matching
BackgroundThe Rapid Evidence Generator (REG) was developed by the AI-based Risk Prediction and Treatment Effect Estimation (AIR_PTE) German-Canadian...
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Noninvasive neuromonitoring with rheoencephalography: a case report
Cerebral blood flow (CBF) autoregulation (AR) can be monitored using invasive modalities, such as intracranial pressure (ICP) and arterial blood...
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Clinical efficacy of moxibustion for ulcerative colitis and its influence on vitamin D receptor
ObjectiveTo observe the clinical efficacy of herbal cake-partitioned moxibustion for ulcerative colitis (UC) and elucidate its mechanism by targeting...
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Quality in Otolaryngology: History, the Current State, and Possible Future Developments
Purpose of ReviewTo help clinicians gain an understanding of quality improvement (QI) and value-based care (VBC) in healthcare, with a specific...
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Serum biomarkers REG1A and REG3A combined with the traditional CEA represent a novel nomogram for the screening and risk stratification of colorectal cancer
BackgroundTo develop and validate a serum protein nomogram for colorectal cancer (CRC) screening.
MethodsThe serum protein characteristics were...
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Regulatory T cells in autoimmune kidney diseases and transplantation
Regulatory T (T reg ) cells that express the transcription factor forkhead box protein P3 (FOXP3) are naturally present in the immune system and have...
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Assessment of therapy response to Regorafenib by 18F-DOPA-PET/CT in patients with recurrent high-grade gliomas: a case series
PurposeRegorafenib (REG) has been recently approved for the treatment of relapsed glioblastoma. Contrast-enhanced (CE) magnetic resonance (MR)...
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Discrete Breast Lump Measurement—a Study of Clinical, Radiological and Histopathological Methods
Oncoplastic Breast Conservation Surgery is increasingly being employed in the management of Early Breast Cancer. The size of the tumour in relation...
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Regulatory T cell-mediated immunosuppression orchestrated by cancer: towards an immuno-genomic paradigm for precision medicine
Accumulating evidence indicates that aberrant signalling stemming from genetic abnormalities in cancer cells has a fundamental role in their evasion...
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A comparison of two techniques of postoperative analgesia: lignocaine-fentanyl intravenous infusion and ropivacaine-fentanyl epidural infusion in patients undergoing cytoreductive cancer surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC)—prospective randomized control study
BackgroundExtensive surgical dissection, hemodynamic alterations associated with cytoreductive surgery (CRS), and hyperthermic intraperitoneal...
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Construction and validation of a prognostic nomogram for predicting cancer-specific survival in patients with intermediate and advanced colon cancer after receiving surgery and chemotherapy
BackgroundExisting predictive models often focus solely on overall survival (OS), neglecting the bias that other causes of death might introduce into...
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Cardiovascular benefits of sodium-glucose cotransporter 2 inhibitors in diabetic and nondiabetic patients
Sodium-glucose cotransporter 2 inhibitors (SGLT2i) were developed as antidiabetic agents, but accumulating evidence has shown their beneficial...
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IL-10 producing regulatory B cells are decreased in blood from smokers and COPD patients
BackgroundTwo opposing B cell subsets have been defined based on their cytokine profile: IL-6 producing effector B cells (B-effs) versus IL-10...
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SGLT2 inhibitors in heart failure with reduced ejection fraction
Sodium – glucose co-transporter 2 (SGLT2) inhibitors reduce blood glucose by inhibiting reabsorption of glucose from the proximal renal tubules....
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Improving attitudes toward trauma-informed care in the neonatal intensive care unit through comprehensive multi-disciplinary education
ObjectiveThis study measured staff understanding and integration of trauma-informed care following comprehensive education.
Study design ... -
Cardiovascular benefits of SGLT2 inhibitors in type 2 diabetes, interaction with metformin and role of erythrocytosis: a self-controlled case series study
BackgroundSodium-glucose cotransporter-2 inhibitors (SGLT2i) have proven cardiovascular benefits in patients with type 2 diabetes (T2D). This...
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Somatic copy number alteration and fragmentation analysis in circulating tumor DNA for cancer screening and treatment monitoring in colorectal cancer patients
BackgroundAnalysis of circulating free DNA (cfDNA) is a promising tool for personalized management of colorectal cancer (CRC) patients. Untargeted...
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Risk factors for cancer-related fatigue in patients with colorectal cancer: a systematic review and meta-analysis
PurposeCancer-related fatigue seriously affects the quality of life of cancer patients, yet few systematic reviews have evaluated the risk factors...
