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Endoscopic loco-regional treatment in controlling pancreatic neuroendocrine tumors (PNETs) behavior: a case series and literature review
Pancreatic neuroendocrine tumors (PNETs) are considered rare pancreatic neoplasms, and it is a challenging disease entity due to its indolent...
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Misdiagnosed cystic pancreatic neuroendocrine tumor with bilobar hepatic metastasis managed with single-stage resection — a case report
BackgroundPancreatic neuroendocrine tumors (PNET) account for less than 2% of all pancreatic tumors, while cystic PNETs account for only 10–18% of...
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Preoperative prediction of pancreatic neuroendocrine tumor grade based on 68Ga-DOTATATE PET/CT
ObjectiveTo establish a prediction model for preoperatively predicting grade 1 and grade 2/3 tumors in patients with pancreatic neuroendocrine tumors...
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A Machine Learning Approach Using [18F]FDG PET-Based Radiomics for Prediction of Tumor Grade and Prognosis in Pancreatic Neuroendocrine Tumor
PurposeWe sought to develop and validate machine learning (ML) models for predicting tumor grade and prognosis using 2-[ 18 F]fluoro-2-deoxy-D-glucose...
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Tumor-to-tumor metastasis of colon cancer metastasizing to a pancreatic neuroendocrine tumor associated with von Hippel-Lindau disease: a case report
Von Hippel-Lindau disease (VHL) is frequently associated with pancreatic neuroendocrine tumors (PNETs). Here, we report a case of tumor-to-tumor...
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Prospective study on stereotactic body radiotherapy for small pancreatic neuroendocrine tumors: tolerance and effectiveness analysis
IntroductionSurgery is the standard treatment for pancreatic neuroendocrine tumors (pNETs), obtaining favorable results but associating high...
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Differentiating small (< 2 cm) pancreatic ductal adenocarcinoma from neuroendocrine tumors with multiparametric MRI-based radiomic features
ObjectivesTo assess MR-based radiomic analysis in preoperatively discriminating small (< 2 cm) pancreatic ductal adenocarcinomas (PDACs) from...
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Review of Merkel cell carcinoma with solitary pancreatic metastases mimicking primary neuroendocrine tumor of the pancreas
Objective/BackgroundMerkel cell carcinoma (MCC) but metastases to the pancreas are very rare. There are only a few cases of isolated metastases of...
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Current standards in the surgical treatment of pancreatic and small intestinal neuroendocrine tumors
Pancreatic and small intestinal neuroendocrine tumors comprise relatively rare and distinctly heterogenous tumor entities which need to be managed...
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Optimal surgical management of unifocal vs. multifocal NF-PNETs: a respective cohort study
BackgroundPancreatic neuroendocrine tumors (PNETs) represent 1–2% of pancreatic tumors, with recent guidelines recommending active surveillance for...
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Long-Term Outcomes of Tuberous Sclerosis Complex-Associated Non-functional Pancreatic Neuroendocrine Tumors: Should We Be More Conservative?
BackgroundHereditary syndromes such as tuberous sclerosis complex (TSC) account for 10% of pancreatic neuroendocrine tumors (PNETs). Surgical...
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Surgical resection of double advanced pancreatic neuroendocrine tumors with multiple renal cell carcinoma associated with von Hippel–Lindau disease
Von Hippel–Lindau (VHL) disease, an autosomal dominant genetic disorder caused by a germline mutation, is associated with non-functional and...
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Efficacy of endoscopic ultrasound-guided tissue acquisition for solid pancreatic lesions 20 mm or less in diameter suspected as neuroendocrine tumors or requiring differentiation
BackgroundFor non-functioning pancreatic neuroendocrine tumors (pNETs) ≤ 20 mm, most guidelines consider follow-up observations as an option;...
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Pathological complete response of initially unresectable multiple liver metastases achieved using combined peptide receptor radionuclide therapy and somatostatin analogs following pancreatic neuroendocrine tumor resection: a case report
BackgroundPeptide receptor radionuclide therapy (PRRT) serves as a novel and effective treatment option for somatostatin receptor-positive...
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Recent progress of experimental model in pancreatic neuroendocrine tumors: drawbacks and challenges
The neuroendocrine neoplasm, in general, refers to a heterogeneous group of all tumors originating from peptidergic neurons and neuroendocrine cells....
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A duodenal gastrointestinal stromal tumor mimicking a pancreatic neuroendocrine tumor: a case report
BackgroundDuodenal gastrointestinal stromal tumors are rare. If tumor growth is extraluminal and involves the head of the pancreas, the diagnosis of...
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Systemic Therapy for Pancreatic Neuroendocrine Tumors
Pancreatic neuroendocrine tumors (PanNETs) account for approximately 2% of all pancreatic malignancies. Several systemic treatment options have been...
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SQSTM1/p62 is a prognostic molecular marker and potential therapeutic target for pancreatic neuroendocrine tumours
BackgroundThere have been few studies on the role of autophagy in pancreatic neuroendocrine tumours (PNETs). SQSTM1/p62 (also called Sequestosome 1)...
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Application of spectral CT combined with perfusion scan in diagnosis of pancreatic neuroendocrine tumors
BackgroundPancreatic neuroendocrine tumors (pNETs) are heterogeneous tumors from the pancreatic neuroendocrine system, and early diagnosis is...
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Current status of the role of endoscopy in evaluation and management of gastrointestinal and pancreatic neuroendocrine tumors
The incidence of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) has increased over the last several decades. In general, NETs are...
