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Deciphering nociplastic pain: clinical features, risk factors and potential mechanisms
Nociplastic pain is a mechanistic term used to describe pain that arises or is sustained by altered nociception, despite the absence of tissue...
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Centralized nociplastic pain causing fibromyalgia: an emperor with no cloths?
The leading school of thought views fibromyalgia as a central sensitization syndrome. Nociplastic pain is the recently proposed term to...
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Assessing the effects of distinct biologic therapies on rheumatoid arthritis pain by nociceptive, neuropathic and nociplastic pain components: a randomised feasibility study
BackgroundPain management is a major unmet need in people with rheumatoid arthritis (RA). Although many patients are treated with disease modifying...
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Association between nociplastic pain and premature endocrine therapy discontinuation in breast cancer patients
PurposeAt least 5 years of adjuvant endocrine therapy (ET) is recommended for patients with hormone receptor-positive invasive breast cancer to...
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Nociplastic pain concept, a mechanistic basis for pragmatic approach to fibromyalgia
Nociplastic pain (NP), as a mechanistic term, denotes pain arising from altered nociception without clear evidence of tissue or somatosensory damage....
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Cannabis-Based Medicines and Medical Cannabis in the Treatment of Nociplastic Pain
Nociplastic pain is defined as pain due to sensitization of the nervous system, without a sufficient underlying anatomical abnormality to explain the...
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Phenoty** of chronic pain in breast cancer survivors: an original study using the cancer pain phenoty** (CANPPHE) Network multidisciplinary international guidelines
PurposeThe primary aim of this cross-sectional study is to examine the prevalence of pain phenotypes in breast cancer survivors (BCS). A secondary...
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Microbiological and Physiological Effects of Pain
Pain is an important innate defense mechanism that can dramatically alter a person’s quality of life. Understanding the microbiological and...
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Pharmacologic Management of Cancer-Related Pain in Pregnant Patients
Despite being an essential part of whole-person care, patients with cancer often experience complex and under-treated pain. Managing cancer-related...
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The potent analgesia of intrathecal 2R, 6R-HNK via TRPA1 inhibition in LF-PENS-induced chronic primary pain model
BackgroundChronic primary pain (CPP) is an intractable pain of unknown cause with significant emotional distress and/or dysfunction that is a leading...
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Subgroup characteristics in care workers with low back pain: cluster analysis-based severity of central sensitivity syndromes and low back pain
PurposeThis multicentre, collaborative, cross-sectional study aimed to explore the characteristics of subgroups based on central sensitivity...
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Pathology of pain and its implications for therapeutic interventions
Pain is estimated to affect more than 20% of the global population, imposing incalculable health and economic burdens. Effective pain management is...
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Chronic pain healthcare workers’ challenges in pain management and receptiveness towards VR as an adjunct management tool: a qualitative study
BackgroundChronic pain is often a debilitating condition that affects individuals physically and mentally. Reliance on pharmacotherapy for pain...
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Clinical Assessment of Osteoarthritis Pain: Contemporary Scenario, Challenges, and Future Perspectives
The multifaceted nature of osteoarthritis (OA) pain presents a challenge in understanding and managing the condition. The diverse pain experiences,...
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Broadening the Scope of Resilience in Chronic Pain: Methods, Social Context, and Development
Purpose of ReviewA wellspring of new research has offered varying models of resilience in chronic pain populations; however, resilience is a...
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Assessing Risk Factors and Comorbidities in the Treatment of Chronic Pain: A Narrative Review
Purpose of ReviewChronic pain affects a significant portion of the population globally, making it a leading cause of disability. Understanding the...
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Effects of interdisciplinary pain rehabilitation programs on neuropathic and non-neuropathic chronic pain conditions – a registry-based cohort study from Swedish Quality Registry for Pain Rehabilitation (SQRP)
Background and aimNeuropathic pain arises as a direct consequence of a lesion or disease affecting the somatosensory system. Pharmacological...
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Integrative Approaches for Cancer Pain Management
Purpose of ReviewThe goal of this review is to summarize updates to the broad array of complementary therapies available for cancer pain. This paper...
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Identification, Evaluation, and Management of Post-breast Surgery Pain Syndrome
Purpose of ReviewThe purpose of this review is to provide a practical framework for the diagnosis and treatment of post-breast surgery pain syndrome.
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Prescription of therapeutic exercise for chronic low back pain management: a narrative review
BackgroundThe results of recent systematic reviews have concluded that most exercise types are more effective than minimal treatment for improving...
