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Serum levels of neurofilament light chains in pediatric multiple sclerosis: a systematic review and meta-analysis
BackgroundMultiple sclerosis is a neuro-inflammatory disease that affects adults and children and causes somatic and cognitive symptoms. Diagnosis...
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Neurofilament light chains to assess sepsis-associated encephalopathy: Are we on the track toward clinical implementation?
Sepsis is the most common cause of admission to intensive care units worldwide. Sepsis patients frequently suffer from sepsis-associated...
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Neurofilament light chains in serum as biomarkers of axonal damage in early MS lesions: a histological–serological correlative study
Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease associated with axonal injury, and neurofilament light chains in serum (sNfL)...
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Neurofilament-light chains (NF-L), a biomarker of neuronal damage, is increased in patients with severe sarcopenia: results of the SarcoPhAge study
BackgroundAs clinical tests, such as gait speed, require nervous system integrity to be performed properly, sarcopenia shares features with...
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Serum neurofilament light chain associates with symptom burden in Lyme neuroborreliosis patients: a longitudinal cohort study from Norway
ObjectivesSerum neurofilament light chain (sNfL), an indicator of neuronal damage, is increasingly recognized as a potential biomarker for disease...
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Correlation analysis between smoke exposure and serum neurofilament light chain in adults: a cross-sectional study
BackgroundSmoke exposure is a prevalent and well-documented risk factor for various diseases across different organ systems. Serum neurofilament...
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Serum neurofilament light chain levels are associated with all-cause mortality in the general US population
IntroductionSerum neurofilament light chain (sNfL) levels are biomarkers of neuro-axonal injury in multiple neurological diseases. Little is known on...
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Validity of serum neurofilament light chain as a prognostic biomarker of disease activity in multiple sclerosis
Multiple sclerosis (MS) is a chronic demyelinating and neuroinflammatory disease of the human central nervous system with complex pathoetiology,...
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The myth of brain damage: no change of neurofilament light chain during transient cognitive side-effects of ECT
Electroconvulsive therapy (ECT) is an effective, safe, and mostly well-tolerated treatment for patients with severe or difficult to treat depression...
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Association between urinary glyphosate levels and serum neurofilament light chain in a representative sample of US adults: NHANES 2013–2014
BackgroundGlyphosate, the herbicide with the highest global usage, has been found to have links to neurological impairment in some occupational...
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Serum neurofilament light in professional soccer players: goal on safety
BackgroundSports-related concussion (SRC) is a subset of mild traumatic brain injuries occurring in contact sports. Most people recover...
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Neurofilament light chain concentration in an aging population
BackgroundNeurofilament light chain (NF-L) concentration is recognized to be modified in neurological diseases and traumatic brain injuries, but...
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Elevated serum Neurofilament Light chain (NfL) as a potential biomarker of neurological involvement in Myotonic Dystrophy type 1 (DM1)
BackgroundCognitive and behavioural symptoms due to involvement of the central nervous system (CNS) are among the main clinical manifestations of...
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Neurofilament-Leichtketten (NFL) als prognostischer Biomarker in der Diagnostik der multiplen Sklerose
This overview of the biomarker neurofilament light chains (NFL) is published as part of the “Biomarker” series of the Central Journal for...
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Diagnostic utility of neurofilament markers for MND is limited in restricted disease phenotype and for differentiation from compressive myeloradiculopathies
Misdiagnosis is frequent in early motor neuron disease (MND), typically compressive radiculopathy, or in patients with restricted MND phenotype. In...
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Association of serum neurofilament light chain levels with clinicopathology of chronic inflammatory demyelinating polyneuropathy, including NF155 reactive patients
ObjectivesTo clarify whether serum neurofilament light chains (NfLs) serve as a biomarker of axonal damage in patients with chronic inflammatory...
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Neurofilament light is a biomarker of brain involvement in lupus and primary Sjögren’s syndrome
BackgroundTo test the hypothesis that neurofilament light (NfL) in CSF is a biomarker of CNS involvement in patients with systemic lupus...
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The role of neurofilament light chain in frontotemporal dementia: a meta-analysis
Frontotemporal dementia (FTD) is the second most frequent dementia, after Alzheimer’s, in patients under the age of 65. It encompasses clinical...
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Neuropathological hints from CSF and serum biomarkers in corticobasal syndrome (CBS): a systematic review
Corticobasal syndrome (CBS) is a clinical syndrome determined by various underlying neurodegenerative disorders requiring a pathological assessment...
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The implication of blue light-emitting diode on mesenchymal stem cells: a systematic review
The application of blue light (400–480 nm) in photobiotherapy remains controversial. This systematic review aimed to collect and analyze the...
