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Recent Updates in Understanding NSAID Hypersensitivity
Purpose of ReviewTo provide a review of available literature regarding nonsteroidal anti-inflammatory drug (NSAID) hypersensitivity with an emphasis...
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Diagnostic evaluation of hypersensitivity reactions to arylpropionic acid derivatives: a descriptive observational study focusing on clinical characteristics and potential risk factors in children
BackgroundArylpropionic acid derivatives (APs) are the main triggers of nonsteroidal anti-inflammatory drug (NSAID) hypersensitivity. Data on...
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Risk factors for drug hypersensitivity reactions in children
Drug hypersensitivity reactions are common in children. Risk factors predisposing to IgE-mediated drug allergies and delayed drug reactions are a...
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The Safety and Accuracy of Drug Patch Testing in Delayed Hypersensitivity Reactions
Purpose of ReviewAdverse drug reactions are common in both the inpatient and outpatient settings and lead to limitations in future treatment options....
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Premedication Protocols to Prevent Hypersensitivity Reactions to Chemotherapy: a Literature Review
Hypersensitivity reactions (HSRs) to chemotherapy may prevent patients from receiving the most effective therapy. This review was undertaken to...
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Acetylsalicylic acid challenge or desensitization in sensitive patients with cardiovascular disease
The use of acetylsalicylic acid (ASA) is problematic in subjects with histories of hypersensitivity reactions (HRs) to it or with cross-reactive...
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Non-IgE-Mediated Drug Hypersensitivity Reactions
Purpose of ReviewNon-IgE-mediated drug reactions have traditionally been poorly defined and studied, though they are the most common form of...
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Hypersensitivity reactions to non-steroidal anti-inflammatory drugs: results of an Austrian cohort study
BackgroundHypersensitivity to non-steroidal anti-inflammatory drugs (NSAIDs) is the second most common cause of drug hypersensitivity. Despite the...
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Mast Cells in Aspirin-Exacerbated Respiratory Disease
Purpose of ReviewAspirin-exacerbated respiratory disease (AERD) is a syndrome of high type 2 inflammation and is known to critically involve mast...
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Stellenwert von ASS-Provokationen beim Analgetika-Intoleranz-Syndrom
BackgroundNonsteroidal anti-inflammatory drug-exacerbated respiratory disease (N-ERD) is often characterized by a severe course of chronic...
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A case of possible anaphylaxis to ASA and structurally unrelated NSAIDs
BackgroundNon-steroidal anti-inflammatory drugs (NSAIDs) are one of the most commonly used classes of medications, and are among the leading causes...
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Drug Hypersensitivity Quality of Life Questionnaire: validation procedures and first results of the Portuguese version
BackgroundHypersensitivity reactions to drugs are unpredictable and can be very complex and severe, even life threatening. Assess its impact on...
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Pulsed Shortwave Therapy in Cervical Osteoarthritis: an NSAID- Controlled, Randomized Clinical Trial
Assess treatment superiority of pulsed shortwave therapy (PSWT) against COX-2 NSAID therapy, in reducing disability and pain due to cervical...
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Respiratory Exposure Tests in Aspirin Exacerbated Respiratory Disease
Purpose of reviewControlled oral provocation test with aspirin is considered the “gold standard” for diagnosing hypersensitivity to NSAIDs...
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Aspirin Desensitization in Treatment of Chronic Rhinosinusitis with Nasal Polyposis: Current Protocols and Evidence
Purpose of ReviewAspirin-exacerbated respiratory disease (AERD), or NSAID-exacerbated respiratory disease (NERD), is a heterogeneous inflammatory...
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Genetic Variants Associated With Drug-Induced Hypersensitivity Reactions: towards Precision Medicine?
Purpose of reviewDrug hypersensitivity represents an important problem for health care and patient’s management, as they limit therapeutic decisions,...
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Drug hypersensitivity in children: a retrospective analysis of 101 pharmacovigilance reports
Our objective was to describe and discuss management of recent cases of drug hypersensitivity in children reported in a pharmacovigilance center. Two...
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NSAID-ERD Syndrome: the New Hope from Prevention, Early Diagnosis, and New Therapeutic Targets
Purpose of ReviewThis review summarizes the latest information on the appropriate identification, evaluation, and treatment of patients with...
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Non-steroidal Anti-inflammatory Drugs: Clinical Implications, Renal Impairment Risks, and AKI
Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most common class of drugs utilized for a variety of disorders, including headaches,...
