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Clinical effectiveness of reduction and fusion versus in situ fusion in the management of degenerative lumbar spondylolisthesis: a systematic review and meta-analysis
PurposeTo compare the clinical effectiveness of reduction and fusion with in situ fusion in the management of patients with degenerative lumbar...
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Image fusion guidance for left subclavian artery in situ fenestration during thoracic endovascular repair
ObjectivesTo evaluate the feasibility and clinical benefit of utilizing image fusion for thoracic endovascular repair (TEVAR) with in situ...
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Fluorescent in situ hybridization has limitations in screening NRG1 gene rearrangements
BackgroundNRG1 fusion is a promising therapeutic target for various tumors but its prevalence is extremely low, and there are no standardized testing...
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Fusion with and without lever reduction in degenerative lumbar spondylolisthesis: a retrospective study
BackgroundThe reduction of slipped vertebra is often performed during surgery for degenerative lumbar spondylolisthesis (DLS). This approach, while...
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Identification of a novel fusion gene, RARA::ANKRD34C, in acute promyelocytic leukemia
Acute promyelocytic leukemia (APL) is a specific subtype of acute myeloid leukemia that is distinguished by the chromosomal translocation...
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Anterior cervical X-shape-corpectomy and fusion vs. anterior cervical corpectomy and fusion for two-level cervical spondylosis
PurposeAnterior cervical X -shape-corpectomy and fusion (ACXF) is a novel cervical surgery, designed as partial alternative to the classic technique,...
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Early gastric cancer with RhoGAP fusion is linked to frequent nodal metastasis and a part of microtubular–mucocellular histology
IntroductionGastric cancer with fusion genes involving the Rho GTPase-activating protein domain (RhoGAP-GC) is mainly included in the genomically...
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Identifification of a novel LDLR-RET Fusion in Lung Adenocarcinoma
BackgroundREarranged during Transfection (RET) gene fusion is one of the common oncogenic variants detectable in non-small cell lung cancer (NSCLC)....
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Is posterior vertebral arthrodesis at the end of the electromagnetic rod lengthening program necessary for all patients? Comparative analysis of sixty six patients who underwent definitive spinal arthrodesis and twenty four patients with in situ lengthening rods
PurposeMagnetically controlled growing rods (MCGR) should be removed or changed at most two years after their implantation in the treatment of...
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Identification of a novel MEF2C::SS18L1 fusion in childhood acute B-lymphoblastic leukemia
PurposeLeukemia-associated fusion genes are closely related to the occurrence, development, diagnosis, and treatment of leukemia. DNA microarrays and...
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Panel-based RNA fusion sequencing improves diagnostics of pediatric acute myeloid leukemia
New methods like panel-based RNA fusion sequencing (RNA-FS) promise improved diagnostics in various malignancies. We here analyzed the impact of...
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Prevalence and clinico-genomic characteristics of patients with TRK fusion cancer in China
Neurotrophic tyrosine kinase ( NTRK ) fusions involving NTRK1 , NTRK2 , and NTRK3 were found in a broad range of solid tumors as driver gene variants....
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A review of MRI (CT)/US fusion imaging in treatment of breast cancer
The ultrasound fusion imaging system is a diagnostic device developed in Japan that utilizes ultrasound and magnetic positioning/navigation. A...
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Unusual split green-orange signals in USP6 fluorescence in situ hybridization in a malignant peripheral nerve sheath tumor with a novel NF1-SCIMP fusion: a potential diagnostic pitfall
Deletion of the neurofibromatosis 1 ( NF1 ) gene is common, but NF1 rearrangement or fusion has rarely been reported in peripheral nerve sheath tumors....
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Blockade of the lncRNA-DOT1L-LAMP5 axis enhances autophagy and promotes degradation of MLL fusion proteins
BackgroundMixed-lineage leukemia ( MLL ) fusion gene caused by chromosomal rearrangement is a dominant oncogenic driver in leukemia. Due to having...
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Individualized detection of TMPRSS2-ERG fusion status in prostate cancer: a rank-based qualitative transcriptome signature
BackgroundTMPRSS2-ERG (T2E) fusion is highly related to aggressive clinical features in prostate cancer (PC), which guides individual therapy....
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Novel NONO::TFE3 fusion and ALK co-expression identified in a subset of cutaneous microcystic/reticular schwannoma
Microcystic/reticular schwannoma (MRS) is a benign variant of schwannoma with a predilection for the gastrointestinal tract and skin. To date,...
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Drug eluting bioactive glass ceramics for fusion in spondylodiscitis: a pilot study
Retrospective observational study. To determine the efficacy and safety of bioactive glass ceramics mixed with autograft in the treatment of...
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A novel EWSR1-MYB fusion in an aggressive advanced breast adenoid cystic carcinoma with mixed classical and solid-basaloid components
Breast adenoid cystic carcinoma (AdCC) with a solid-basaloid component is rare. The solid-basaloid component is usually characterized by solid nests...
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Characteristics and literature review of ETV6::ABL1 fusion gene-positive acute myeloid leukemia
ObjectiveTo describe the features of ETV6::ABL1 AML as well as the clinical treatment and outcomes.
MethodsClinical data were collected from three...