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Re-irradiation spine stereotactic body radiotherapy following high-dose conventional radiotherapy for metastatic epidural spinal cord compression: a retrospective study
PurposeWe aimed to evaluate the efficacy and safety of re-irradiation stereotactic body radiation therapy (SBRT) in patients with metastatic...
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Long-term outcomes of high-dose-rate brachytherapy and external beam radiotherapy without hormone therapy for high-risk localized prostate cancer
PurposeUntil March 2018, patients with high-risk localized prostate cancer had been administered high-dose-rate brachytherapy (HDR-BT) combined with...
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Post-operative KEloids iRradiation (POKER): does the surgery/high-dose interventional radiotherapy association make a winning hand?
PurposeTo report the results involving post-operative interventional radiotherapy (POIRT) in a homogenous cohort of patients affected by keloid and...
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High vs. low radiotherapy dose in locally advanced esophageal squamous cell carcinoma patients treated with neoadjuvant concurrent chemoradiotherapy: an endemic area population-based study
BackgroundThe optimal radiotherapy dose for locally advanced esophageal squamous cell carcinoma in endemic areas treated with neoadjuvant concurrent...
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Low rate of function-limiting side effects with high-dose adjuvant radiotherapy in high-grade soft tissue extremity sarcomas: a retrospective single-center analysis over 10 years
BackgroundOver the years, radiotherapy has been established as a tool to improve local control for high-grade sarcomas. Although the European Society...
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The “Combo” radiotherapy treatment for high-risk grade 2 meningiomas: dose escalation and initial safety and efficacy analysis
PurposeThe subgroup “high-risk” WHO grade 2 (hRG2) meningiomas may benefit from adjuvant radiation therapy (RT), but results are still suboptimal...
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Comparison of outcomes in high-risk prostate cancer patients treated with low-/high-dose-rate brachytherapy plus external beam radiotherapy
BackgroundAlthough brachytherapy is a standard treatment option for patients with high-risk prostate cancer, only a few studies have compared...
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Pilot Evaluation of Perioperative High Dose Rate Brachytherapy in Head Neck Cancers
Perioperative high dose rate brachytherapy involves insertion of brachytherapy catheter over the tumor bed during surgical removal of disease...
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Hypofractionated re-irradiation with bevacizumab for relapsed chemorefractory glioblastoma after prior high dose radiotherapy: a feasible option for patients with large-volume relapse
PurposeThere remains no standard of care for patients with recurrent and chemorefractory glioblastoma. Re-irradiation (reRT) provides an additional...
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Clinical application of 192Ir High-Dose-Rate brachytherapy in metastatic lymph nodes of the neck
ObjectiveThe objective of this study was to investigate the safety and effectiveness of high-dose-rate brachytherapy as a treatment modality for...
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Measurement of the distance between tumor micro-foci and gross tumor in rectal cancer pathological specimens: implication on margin distance of clinical target volume treated with high-dose radiotherapy for rectal cancer
PurposeTo measure the micro-foci distance away from gross tumor and to provide reference to create the clinical target volume (CTV) margin for boost...
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High-dose planned adaptive helical tomotherapy for cutaneous angiosarcoma of the scalp
PurposeThe purpose of this study was to investigate the feasibility and effectiveness of high-dose planned adaptive intensity-modulated radiation...
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Low- vs. high-dose radiotherapy in Graves’ ophthalmopathy: a retrospective comparison of long-term results
PurposeRadiotherapy represents an effective treatment option in Graves’ ophthalmopathy (GO), leading to palliation of clinical symptoms. However,...
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Opportunities and challenges in combining immunotherapy and radiotherapy in esophageal cancer
BackgroundImmunotherapy has shown promise in the treatment of esophageal cancer, but using it alone only benefits a small number of patients. Most...
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Hypofractionated versus conventional fractionation external beam radiotherapy in intermediate and high risk localized prostate cancer
BackgroundProstate cancer is the second most common malignancy in men, and its incidence is increasing which is attributed to increased screening...
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High-dose radiation-resistant lung cancer cells stored many functional lipid drops through JAK2/p-STAT3/FASN pathway
BackgroundThe understanding of radiation resistance is still unclear. This study aims to explore the new mechanism of radiation resistance in lung...
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Is reduced-dose whole-brain radiotherapy also feasible in primary CNS lymphoma for curative or salvage purpose?
PurposeRecently, reduced-dose whole-brain radiotherapy (WBRT) has been used to treat primary central nervous system lymphoma (PCNSL). However,...
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Efficacy and Safety of Adjuvant Radiotherapy for Soft Tissue Sarcoma: A Two-Institution Retrospective Observational Study
The recommended post-operative radiotherapy dose of approximately 60 Gy may be reduced during treatment planning, and the optimal irradiation method...
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Towards clinical translation of FLASH radiotherapy
The ultimate goal of radiation oncology is to eradicate tumours without toxicity to non-malignant tissues. FLASH radiotherapy, or the delivery of...
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Quality requirements for MRI simulation in cranial stereotactic radiotherapy: a guideline from the German Taskforce “Imaging in Stereotactic Radiotherapy”
Accurate Magnetic Resonance Imaging (MRI) simulation is fundamental for high-precision stereotactic radiosurgery and fractionated stereotactic...
