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The effects of cocoa flavanols on indices of muscle recovery and exercise performance: a narrative review
AbstractExercise-induced muscle damage (EIMD) is associated with oxidative stress and inflammation, muscle soreness, and reductions in muscle...
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Fuzzy identification of bioactive components for different efficacies of rhubarb by the back propagation neural network association analysis of UPLC-Q-TOF/MSE and integrated effects
BackgroundRhei Radix et Rhizoma (rhubarb), as one of the typical representatives of multi-effect traditional Chinese medicines (TCMs), has been...
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Effect of home-based lifestyle interventions on cognition in older adults with mild cognitive impairment: a systematic review
BackgroundMild Cognitive Impairment (MCI) is frequently a precursor to dementia, affecting aspects of cognition such as language, thinking, or...
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Dietary Polyphenols: What is the Estimated Intake in Population Studies With Adults and Elderly People?
AbstractEstimates of dietary intake of polyphenols have been limited to specific samples from certain population groups, and different databases have...
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Mental Performance and Sport: Caffeine and Co-consumed Bioactive Ingredients
The plant defence compound caffeine is widely consumed as a performance enhancer in a sporting context, with potential benefits expected in both...
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Quercetin for inhibition of inflammatory responses and oxidative stress in lung injury model: a systematic review and meta-analysis
Acute lung injury (ALI) is a life-threatening clinical syndrome with high morbidity and mortality. The main pathological features of ALI are...
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Grape Seed Components as Protectors of Inflammation, DNA Damage, and Cancer
Purpose of ReviewOxidative stress is related to the pathogenesis of several chronic diseases, including inflammatory processes. Free radicals excess...
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Dietary polyphenols and the risk of metabolic syndrome: a systematic review and meta-analysis
BackgroundAccumulating evidence has suggested that dietary polyphenols may be protective against metabolic syndrome (MetS); however, the available...
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Use of monomeric and oligomeric flavanols in the dietary management of patients with type 2 diabetes mellitus and microalbuminuria (FLAVA trial): study protocol for a randomized controlled trial
BackgroundPatients with type 2 diabetes mellitus (T2D) are prone to micro- and macro-vascular complications. Monomeric and oligomeric flavanols (MOF)...
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Phenolic-rich fraction of green tea attenuates histamine-mediated cardiopulmonary toxicity by inhibiting Cox-2/NF-κB signaling pathway and regulating oxidant/antioxidant balance
BackgroundHistamine (HIS) has a substantial impact on the development of numerous allergic disorders including asthma. Antihistamines mostly target...
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Liver cancer wars: plant-derived polyphenols strike back
Liver cancer currently represents the leading cause of cancer-related death worldwide. The majority of liver cancer arises in the context of chronic...
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Cocoa Consumption Decreases Oxidative Stress, Proinflammatory Mediators and Lipid Peroxidation in Healthy Subjects: A Randomized Placebo-Controlled Dose-Response Clinical Trial
IntroductionCocoa flavonoids have been described to reduce the cardiovascular risk. Nevertheless, the involved mechanisms should be clarified and the...
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Effect of Polyphenols on Cognitive Function: Evidence from Population-based Studies and Clinical Trials
Due to progressive population aging, a new dementia case occurs at every 3 seconds, placing a heavy burden of disease. Identifying potential risk or...
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Greasing the Wheels of Pharmacotherapy for Colorectal Cancer: the Role of Natural Polyphenols
Purpose of ReviewThe main purpose of this review, mainly based on preclinical studies, is to summarize the pharmacological and biochemical evidence...
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How to Tackle Mental Fatigue: A Systematic Review of Potential Countermeasures and Their Underlying Mechanisms
IntroductionMental fatigue (MF) is a psychobiological state that impairs cognitive as well as physical performance in different settings. Recently,...
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Effects of dietary supplements, foods, and dietary patterns in Parkinson’s disease: meta-analysis and systematic review of randomized and crossover studies
BackgroundDiet significantly impacts Parkinson’s disease (PD) with plausible biological hypotheses. Although the thesis has been explored in several...
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Polyphenols mediated attenuation of diabetes associated cardiovascular complications: A comprehensive review
BackgroundDiabetes mellitus is a common chronic metabolic disorder that is characterized by increased levels of glucose for prolonged periods of...
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Harnessing Plant Flavonoids to Fight Pancreatic Cancer
Purpose of ReviewThis review draws on the last fifteen years (2009–2024) of published data to summarize the potential effect of plant flavonoids on...
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Bioactives in the Food Supply: Effects on CVD Health
Purpose of ReviewInterest in preventing atherosclerosis and cardiovascular disease extends beyond essential nutrients and dietary patterns. This...