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Progress of SGLT2 inhibitors in the treatment of common immune-related nephropathies
The immune system can lead to a variety of renal diseases through direct or indirect mechanisms. In immune-mediated nephropathy, though standardized...
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Non-diabetic nephropathy in diabetic patients: incidence, HbA1c variability and other predictive factors, and implications
PurposeDiabetes mellitus (DM) is the leading cause of chronic kidney disease (CKD) in the population. In patients with diabetes mellitus, the...
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Diagnostic utility of renal shear wave elastography and renal Doppler findings in diabetic nephropathy: a case–control study
BackgroundDiabetes mellitus is a common systemic disease that affects the kidneys and could eventually develop an end-stage renal failure. Renal...
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Prevalence and risk factors of poor glycemic control and diabetic nephropathy among patients with type 2 diabetes mellitus in Dhamar, Yemen
BackgroundGlycemic control is a significant step in reducing diabetic complications. The purpose of this study was to determine the prevalence and...
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Repurposing fexofenadine as a promising candidate for diabetic kidney disease: randomized clinical trial
PurposeDiabetic kidney disease (DKD) is a devastating complication of diabetes mellitus. Inflammation and histamine are potentially involved in the...
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Evolution and global research trends of immunity in diabetic nephropathy: a bibliometric and visual analysis from 2004 to 2023
BackgroundDiabetic nephropathy (DN) is the leading cause of end-stage renal disease, with an increasing prevalence worldwide, but its pathomechanisms...
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Niclosamide from an anthelmintic drug to a promising adjuvant therapy for diabetic kidney disease: randomized clinical trial
BackgroundDiabetic kidney disease (DKD) is a serious complication that begins with albuminuria and often leads to a rapid progressive decline in...
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Circulating β2 and α1 microglobulins predict progression of nephropathy in diabetic patients: a meta‐analysis of prospective cohort studies
AimsTo study the association of circulating β2 (B2M) and α1 microglobulins (A1M) with diabetic nephropathy (DN) progression, a meta-analysis was...
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Real-World Outcomes of Anti-VEGF Therapy in Diabetic Macular Oedema: Barriers to Treatment Success and Implications for Low/Lower-Middle-Income Countries
Diabetic macular oedema (DMO) is the leading cause of vision loss associated with diabetic eye disease. The exponential increase in the diabetic...
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Efficacy of liraglutide in patients with diabetic nephropathy: a meta-analysis of randomized controlled trials
BackgroundThe efficacy of liraglutide to treat type 2 diabetic nephropathy (T2DN) remains controversial. Thus, we conducted this meta-analysis to...
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Effect of stress hyperglycaemia on acute kidney injury in non-diabetic critically ill patients?
BackgroundStress hyperglycaemia (SH) and acute kidney injury (AKI) occur frequently in critically ill patients, and particularly non-diabetics are...
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A Role for SGLT-2 Inhibitors in Treating Non-diabetic Chronic Kidney Disease
In recent years, inhibitors of the sodium-glucose co-transporter 2 (SGLT2 inhibitors) have been shown to have significant protective effects on the...
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Effect of a sodium restriction diet on albuminuria and blood pressure in diabetic kidney disease patients: a meta-analysis
BackgroundA sodium restriction diet is a key component of chronic kidney disease (CKD) management. However, the efficacy of its use in patients with...
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Anti-vascular endothelial growth factor therapy in diabetic macular edema: real-life outcomes from a multicenter study in Turkey over 36 months
PurposeThis study aimed to report the visual and anatomical outcomes of intravitreal anti-VEGF treatment for diabetic macular edema (DME) in a...
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A stepwise data interpretation process for renal amyloidosis ty** by LMD-MS
BackgroundsSystemic amyloidosis is classified according to the deposited amyloid fibril protein (AFP), which determines its best therapeutic scheme....
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Characteristics of outpatients referred for a first consultation with a nephrologist: impact of different guidelines
IntroductionChronic kidney disease (CKD) affects > 10% of the population but not all CKD patients require referral to a nephrologist. Various...
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Diagnosing Fabry nephropathy: the challenge of multiple kidney disease
Fabry disease (FD) is an X-linked inherited lysosomal disorder due to a deficiency of the enzyme alpha-galactosidase A (α-gla) due to mutations in...
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Efficacy of tripterygium glycosides for diabetic nephropathy: a meta-analysis of randomized controlled trials
BackgroundsDiabetic nephropathy (DN) is one of the most important clinical complications of diabetes mellitus (DM) and is the most common cause of...
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Real-World Diagnosis and Treatment of Diabetic Kidney Disease
IntroductionPeople with type 2 diabetes mellitus (T2DM) and diabetic kidney disease (DKD) have increased morbidity and mortality risk....
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Urinary sediment microRNAs can be used as potential noninvasive biomarkers for diagnosis, reflecting the severity and prognosis of diabetic nephropathy
BackgroundPatients with both diabetes mellitus (DM) and kidney disease could have diabetic nephropathy (DN) or non-diabetic renal disease (NDRD). IgA...