Search
Search Results
-
Pancreatic enlargement in a patient receiving therapy with vasodilators for pulmonary arterial hypertension: a case report
Epoprostenol is a prostacyclin (prostaglandin I2) analog that causes vasodilation and inhibits platelet aggregation and is used in the management of...
-
Short term effect of intravenous treprostinil in term and preterm infants with pulmonary hypertension
BackgroundPulmonary hypertension (PH) is a life-threatening condition in newborns. We aimed to assess the clinical and echocardiographic responses of...
-
A 4-week comparison of capillaroscopy changes, healing effect, and cost-effectiveness of botulinum toxin-A vs prostaglandin analog infusion in refractory digital ulcers in systemic sclerosis
IntroductionSystemic sclerosis (SSc) is a systemic multi-organ disease. Raynaud’s phenomenon (RP) and digital ulcers (DUs) in SSc patients can be...
-
Prostaglandin and prostaglandin receptors: present and future promising therapeutic targets for pulmonary arterial hypertension
BackgroundPulmonary arterial hypertension (PAH), Group 1 pulmonary hypertension (PH), is a type of pulmonary vascular disease characterized by...
-
Intravenous Migraine Treatment in Children and Adolescents
Purpose of ReviewMost treatment algorithms and guidelines for acute intravenous (IV) treatments of migraine for children and adolescents are derived...
-
Future Perspectives of Pulmonary Arterial Hypertension: A Review of Novel Pipeline Treatments and Indications
Pulmonary arterial hypertension is characterized by elevated blood pressure and pathological changes in the pulmonary arterioles, leading to the...
-
Management of AKI in Patients with Cirrhosis
Purpose of ReviewThe development of acute failure of the kidneys in the context of decompensated cirrhosis represents one of the most challenging...
-
2023 Brazilian Society of Rheumatology guidelines for the treatment of systemic sclerosis
BackgroundSystemic sclerosis (SSc) is a rare chronic autoimmune disease with heterogeneous manifestations. In the last decade, several clinical...
-
Efficacy of inhaled iloprost in children with pulmonary hypertension after pediatric cardiac surgery: a case series
BackgroundThe postoperative phase of cardiac surgery in pediatric patients with congenital heart disease often involves the management of pulmonary...
-
Idiopathic Pulmonary Fibrosis: 8 Years On After Nintedanib and Pirfenidone Approval—What Is on the Horizon?
Purpose of ReviewThe approval of nintedanib and pirfenidone has changed the treatment landscape of idiopathic pulmonary fibrosis (IPF); however, both...
-
Prandial Insulins: A Person-Centered Choice
Purpose of ReviewPostprandial hyperglycemia, or elevated blood glucose after meals, is associated with the development and progression of various...
-
The I-MICRO trial, Ilomedin for treatment of septic shock with persistent microperfusion defects: a double-blind, randomized controlled trial—study protocol for a randomized controlled trial
BackgroundSeptic shock remains a significant cause of death in critically ill patients. During septic shock, some patients will retain...
-
Life-threatening PPHN refractory to nitric oxide: proposal for a rational therapeutic algorithm
Persistent pulmonary hypertension of the neonate (PPHN) refractory to inhaled nitric oxide still represents a frequent clinical challenge with...
-
Drug Treatment of Pulmonary Hypertension in Children
Pulmonary arterial hypertension (PAH) is a rare disease in infants and children that is associated with significant morbidity and mortality. The...
-
Pediatric pulmonary hypertension: insulin-like growth factor-binding protein 2 is a novel marker associated with disease severity and survival
BackgroundInsulin-like growth factors (IGFs), and their binding proteins (IGFBPs), play a significant role in cardiovascular function and may...
-
The Effect of Perioperative Administration of Treprostinil in Infants with Non-restrictive Ventricular Septal Defect and Severe Pulmonary Arterial Hypertension
This study investigated the efficacy and safety of intravenous treprostinil during the perioperative period in infants with non-restrictive...
-
Microcirculatory dysfunction in cardiogenic shock
Cardiogenic shock is usually defined as primary cardiac dysfunction with low cardiac output leading to critical organ hypoperfusion, and tissue...
-
Comparing the effects of ketorolac and Paracetamol on postoperative pain relief after coronary artery bypass graft surgery. A randomized clinical trial
IntroductionPain management after coronary artery bypass graft (CABG) surgery remains challenging.
ObjectiveThis study aimed to compare the effects...
-
Early diagnosis and targeted approaches to pulmonary vascular disease in bronchopulmonary dysplasia
AbstractPulmonary hypertension has emerged as a life-threatening disease in preterm infants suffering from bronchopulmonary dysplasia (BPD). Its...
-
What Is the Role of Oral Prostacyclin Pathway Medications in Pulmonary Arterial Hypertension Management?
Purpose of ReviewProstacyclin pathway medications have been shown to be highly efficacious in the treatment of pulmonary arterial hypertension (PAH)...