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GSTO1 aggravates EGFR-TKIs resistance and tumor metastasis via deglutathionylation of NPM1 in lung adenocarcinoma
Despite significantly improved clinical outcomes in EGFR-mutant lung adenocarcinoma, all patients develop acquired resistance and malignancy on the...
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Low-intensity ultrasound inhibits melanoma cell proliferation in vitro and tumor growth in vivo
PurposeTo determine the effect of low-intensity ultrasound on cancer cell proliferation in vitro and tumor growth in vivo.
MethodsIn vitro, several...
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Metabolomic profiles of ovariectomized mice and their associations with body composition and frailty-related parameters in postmenopausal women
BackgroundMenopause, a dramatical estrogen-deficient condition, is considered the most significant milestone in women’s health.
Purpose ...
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Association of cardiac autonomic dysfunction with higher levels of plasma lipid metabolites in recent-onset type 2 diabetes
Aims/hypothesisEmerging evidence suggests that in addition to hyperglycaemia, dyslipidaemia could represent a contributing pathogenetic factor to...
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Secretogranin II influences the assembly and function of MHC class I in melanoma
Melanoma is the deadliest form of skin cancer showing rising incidence over the past years. New insights into the mechanisms of melanoma progression...
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Improve the satisfaction of medical staff on the use of home nursing mobile APP by using a hybrid multi-standard decision model
ObjectiveTo identify critical satisfaction gaps in a home nursing mobile application (APP) using a systematic decision-making model.
Methods ...
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Differences in metabolomic profiles between Black and White women in the U.S.: Analyses from two prospective cohorts
There is growing interest in incorporating metabolomics into public health practice. However, Black women are under-represented in many metabolomics...
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Identification of key potential infection processes and risk factors in the computed tomography examination process by FMEA method under COVID-19
PurposeTo identify the key infection processes and risk factors in Computed Tomography (CT) examination process within the standard prevention and...
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Pre- and postpartum fear of childbirth and its predictors among rural women in China
BackgroundFear of childbirth (FOC) can influence both maternal and child health. Research on FOC in China is scarce, especially on rural women. This...
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Fear of childbirth and its predictors in re-pregnant women after cesarean section: a cross-sectional multicenter study in China
BackgroundSince the implementation of China’s two-child policy in 2016, the number of re-pregnant women after cesarean section has increased...
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A 6-month exercise intervention clinical trial in women: effects of physical activity on multi-omics biomarkers and health during the first wave of COVID-19 in Korea
BackgroundCoronavirus disease 2019 (COVID-19) was first reported in December 2019 and the first case in Korea was confirmed on January 20, 2020. Due...
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Clinical and genetic characteristics of Chinese patients with congenital cranial dysinnervation disorders
BackgroundCongenital cranial dysinnervation disorders (CCDDs) are a group of diseases with high clinical and genetic heterogeneity. Clinical...
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Additional primary malignancies in a Polish cohort of uveal melanoma patients: a review of 644 patients with long-term follow-up
AimTo investigate the frequency and location of additional primary malignancies in a Polish cohort of uveal melanoma (UM) patients registered in a...
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Identification of candidate metabolite biomarkers for metabolic syndrome and its five components in population-based human cohorts
BackgroundMetabolic Syndrome (MetS) is characterized by risk factors such as abdominal obesity, hypertriglyceridemia, low high-density lipoprotein...
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Suicide and other causes of death among Chernobyl cleanup workers from Estonia, 1986 − 2020: an update
Mortality was studied in a cohort of 4831 men from Estonia who participated in the environmental cleanup of the radioactively contaminated areas...
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Head and neck oncology management in the time of COVID-19: results of a head and neck cancer center
PurposeGiven the concerns about the effects of the COVID-19 pandemic on cancer care, we analyzed the treatment quality of the head and neck cancer...
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Suicide risk among adolescents and young adults after cancer diagnosis: analysis of 34 cancer groups from 2009 to 2019
PurposeWe aimed to identify granular groups with an increased risk of suicide among adolescents and young adult (AYA) patients with a previous...
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