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Detection of virus-specific T cells via ELISpot corroborates early diagnosis in human Borna disease virus 1 (BoDV-1) encephalitis
BackgroundWithin endemic regions in southern and eastern Germany, Borna disease virus 1 (BoDV-1) causes rare zoonotic spill-over infections in...
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Healthcare-associated exposure to Borna disease virus 1 (BoDV-1)
The Borna disease virus 1 (BoDV-1) causes severe and often fatal encephalitis in humans. The virus is endemic in parts of Germany, Liechtenstein,...
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No evidence of an association of multiple sclerosis (MS) with Borna disease virus 1 (BoDV-1) infections in patients within an endemic region: a retrospective pilot study
BackgroundBorna disease virus 1 (BoDV-1) causes rare human infections within endemic regions in southern and eastern Germany. The infections reported...
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Word recognition memory and serum levels of Borna disease virus specific circulating immune complexes in obsessive–compulsive disorder
BackgroundBorna disease virus 1 (BoDV-1) is a non-segmented, negative-strand RNA virus that persistently infects mammals including humans. BoDV-1...
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Investigation of fatal human Borna disease virus 1 encephalitis outside the previously known area for human cases, Brandenburg, Germany – a case report
BackgroundThe true burden and geographical distribution of human Borna disease virus 1 (BoDV-1) encephalitis is unknown. All detected cases so far...
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Detection of bornavirus-reactive antibodies and BoDV-1 RNA only in encephalitis patients from virus endemic areas: a comparative serological and molecular sensitivity, specificity, predictive value, and disease duration correlation study
PurposeHuman Borna disease virus (BoDV-1) encephalitis is an emerging disease in Germany. This study investigates the spectrum of human BoDV-1...
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First detected geographical cluster of BoDV-1 encephalitis from same small village in two children: therapeutic considerations and epidemiological implications
BackgroundThe Borna disease virus (BoDV-1) is an emerging zoonotic virus causing severe and mostly fatal encephalitis in humans.
Methods and Results ...
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The neuropathology of fatal encephalomyelitis in human Borna virus infection
After many years of controversy, there is now recent and solid evidence that classical Borna disease virus 1 (BoDV-1) can infect humans. On the basis...
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MiR-1290: a potential therapeutic target for regenerative medicine or diagnosis and treatment of non-malignant diseases
MicroRNAs are a set of small non-coding RNAs that could change gene expression with post-transcriptional regulation. MiRNAs have a significant role...
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Zoonosen bei einheimischen Wildsäugetieren
BackgroundZoonoses are diseases and infections that can be transmitted naturally between animals and humans. Direct and indirect contact of humans...
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Digital ischemic necrosis in a patient with systematic lupus erythematosus patient after severe acute respiratory syndrome coronavirus 2 infection: a case report
BackgroundPatients with coronavirus disease 2019 have a high incidence of thrombosis that decreases after recovery. When coronavirus disease 2019 is...
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Virale Zoonosen in Deutschland aus der One Health-Perspektive
The COVID-19 pandemic and the increasing occurrence of monkeypox (mpox) diseases outside Africa have illustrated the vulnerability of populations to...
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The role of infections and inflammation in schizophrenia: review of the evidence
BackgroundSchizophrenia is a severe mental illness affecting approximately 1% of the population worldwide. While its exact causes remain unknown,...
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Travel-associated neurological disease terminated in a postmortem diagnosed atypical HSV-1 encephalitis after high-dose steroid therapy – a case report
BackgroundHuman encephalitis can originate from a variety of different aetiologies, of which infection is the most common one. The diagnostic work-up...
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Disparities in Social Vulnerability and Premature Mortality among Decedents with Hepatitis B, United States, 2010–2019
BackgroundCurrent US hepatitis B mortality rates remain three times higher than the national target. Mortality reduction will depend on addressing...
