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Ayurvedic Drug Triphala in Combination with Providone Iodine Mitigates Radiation-Induced Mucositis in Head and Neck Cancer Patients without Affecting the Tumor Response
Radiation-induced mucositis is a dose-limiting concern in the treatment of head and neck cancers (HNC). This study was conducted to determine the...
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The effect of systemic application of propolis on tongue damage and oral mucositis in rats exposed to radiation
PurposeIn this experimental study, the effect of dose-dense systemic application of propolis on oral mucosity, histological changes in papilla, and...
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Efficacy of a novel device for cryoprevention of oral mucositis: a randomized, blinded, multicenter, parallel group, phase 3 trial
Cryoprevention (CP) using ice (IC) is an effective strategy to prevent chemotherapy-induced oral mucositis (OM). However, the use of IC may cause...
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Investigation of the protective effect of gel incorporating Eugenia jambolana leaf extract on 5-fluorouracil-induced oral mucositis: an animal study
PurposeThe study aimed to evaluate the possible preventive effect of two concentrations (3 and 5% w/w) of Eugenia jambolana (EJ) extract against...
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Incidence, severity, and temporal development of oral complications in pediatric allogeneic hematopoietic stem cell transplant patients – a multicenter study
PurposeOral mucositis is a common complication for patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT) and causes pain and...
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Photobiomodulation for the management of xerostomia and oral mucositis in patients with cancer: a randomized clinical trial
To evaluate the applicability of photobiomodulation therapy (PBM-T) in the management of xerostomia and OM. Fifty-three patients with head and neck...
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Post hoc analysis of a randomized controlled trial comparing concurrent chemoradiation with cisplatin versus nimotuzumab-cisplatin, focusing on acute oral mucositis
BackgroundAcute oral mucositis has been infrequently studied in the patients with head and neck squamous cell carcinoma (HNSCC) receiving once-weekly...
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Markers of intestinal mucositis to predict blood stream infections at the onset of fever during treatment for childhood acute leukemia
Despite chemotherapy-induced intestinal mucositis being a main risk factor for blood stream infections (BSIs), no studies have investigated mucositis...
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Treatment for Oral Mucositis—Current Options and an Update of Small Molecules Under Development
Despite its history as one of the most impactful toxicities associated with cytotoxic cancer therapy, oral mucositis (OM) remains an unmet clinical...
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Oral mucositis in patients with acute myeloid leukemia treated with allogeneic hematopoietic stem cell transplantation in relation to the conditioning used prior to transplantation
This study was designed to investigate the frequency and severity of oral mucositis in patients with acute myeloid leukemia after allogeneic...
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Low-level laser or LED photobiomodulation on oral mucositis in pediatric patients under high doses of methotrexate: prospective, randomized, controlled trial
PurposeThe objective of the present study was to compare the efficacy of photobiomodulation with low-level laser therapy (LLLT) or light-emitting...
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Most used photobiomodulation dosimetry parameters to treat oral mucositis after preconditioning for hematopoietic stem cell transplantation: systematic review and meta-analysis
Parameter reproducibility in photobiomodulation therapy (PBMT) is still scarce in literature for the management of oral mucositis (OM). This study...
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Do grape and black mulberry molasses have an effect on oral mucositis and quality of life in patients with head and neck cancer?
ObjectiveWe aimed to investigate the effect of black mulberry and grape molasses on the prevention and treatment of oral mucositis and quality of...
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Impact of severe oral mucositis in pediatric cancer patients on resource utilization and cancer treatment plans
Background: Oral mucositis is a common chemotherapy-related adverse event that may result in serious complications. Few studies have evaluated...
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Comparative study of royal jelly, propolis, and photobiomodulation therapies in 5-fluorouracil-related oral mucositis in rats
PurposeThis study aimed to evaluate the effects and mechanisms of action of royal jelly (RJ) and propolis compared to photobiomodulation therapy...
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Effectiveness of glutamine in the management of oral mucositis in cancer patients: a meta-analysis of randomized controlled trials
ObjectiveThe aim of this meta-analysis was to evaluate the effectiveness of glutamine for preventing or treating moderate-to-severe oral mucositis...
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Oral mucositis—case series of a rare adverse effect associated with immunotherapy
Immune checkpoint inhibitors, such as pembrolizumab and nivolumab, act by inhibiting programmed death-1 and activating the T cells against cancer. An...
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Exposure of anti-infective drugs and the dynamic changes of the gut microbiota during gastrointestinal mucositis in autologous stem cell transplant patients: a pilot study
Gastrointestinal mucositis could potentially compromise drug absorption due to functional loss of mucosa and other pathophysiological changes in the...
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Incidence and risk factors for oral mucositis in pediatric patients receiving chemotherapy
PurposeTo investigate the incidence and risk factors for oral mucositis (OM) in patients with childhood cancer undergoing chemotherapy.
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Long-term safety of photobiomodulation therapy for oral mucositis in hematopoietic cell transplantation patients: a 15-year retrospective study
Photobiomodulation therapy (PBMT) has demonstrated efficacy in the prevention and treatment of oral mucositis (OM) in hematopoietic cell...
