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Association between the triglyceride-glucose index and subclinical left ventricular systolic dysfunction in obese patients
BackgroundThe association between the triglyceride–glucose (TyG) index and subclinical left ventricular (LV) systolic dysfunction in obese patients...
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Cystathionine γ-lyase mediates cell proliferation, migration, and invasion of nasopharyngeal carcinoma
Nasopharyngeal carcinoma (NPC) is an epithelia-derived malignancy with a distinctive geographic distribution. Cystathionine γ-lyase (CSE) is involved...
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Colchicine Attenuates Microvascular Obstruction after Myocardial Ischemia-Reperfusion Injury by Inhibiting the Proliferation of Neutrophil in Bone Marrow
PurposeComplete and rapid recanalization of blood flow by percutaneous coronary intervention (PCI) is the most effective intervention for patients...
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Association between triglyceride-glucose index trajectories and carotid atherosclerosis progression
BackgroundThe triglyceride-glucose (TyG) index has been recognized as being an alternative cardiometabolic biomarker for insulin resistance...
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Prediction value of pericoronary fat attenuation index for coronary in-stent restenosis
ObjectivesAs a novel imaging marker, pericoronary fat attenuation index (FAI) reflects the local coronary inflammation which is one of the major...
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Epithelial CRL4DCAF2 Is Critical for Maintaining Intestinal Homeostasis Against DSS-Induced Colitis by Regulating the Proliferation and Repair of Intestinal Epithelial Cells
Background and AimsInflammatory bowel disease (IBD) is currently gaining an increasing global interest. Intestinal epithelial barrier dysfunction is...
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A novel prognostic model for predicting patient survival and immunotherapy responsiveness in hepatocellular carcinoma: insights into the involvement of T-cell proliferation
BackgroundThe cancer-associated biological mechanisms and the implementation of immunotherapy are heavily impacted by the activities of T cells,...
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Upregulation of PCED1B-AS1 in proliferative diabetic retinopathy and its involvement in retinal vascular endothelial cell proliferation
BackgroundThis study was to assess the diagnostic value of PCED1B-AS1 for proliferative diabetic retinopathy (PDR) and investigate the involvement of...
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Effects of biological clock gene BMAL1 and hypoxia-inducible factor HIF-1α on proliferation, migration and radiotherapy sensitivity of nasopharyngeal carcinoma cells HONE1
ObjectiveTo understand the effects of clock gene BMAL1 and HIF-1α(Hypoxia inducible factor-1α) on proliferation, migration and sensitivity to...
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Prognostic value of triglyceride glucose index in population at high cardiovascular disease risk
BackgroundEarly identification of populations at high cardiovascular disease (CVD) risk and improvement of risk factors can significantly decrease...
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Prognostic value of the systemic immune-inflammation index in patients with upper tract urothelial carcinoma after radical nephroureterectomy
BackgroundTo investigate the prognostic significance of the systemic immune-inflammation index (SII) for patients with upper tract urothelial...
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RETRACTED ARTICLE: Silencing POLE2 promotes apoptosis and inhibits proliferation of oral squamous cell carcinomas by inhibiting PI3K/AKT signaling pathway
Oral squamous cell carcinoma is the most common malignant tumor in the head and neck at present, but the mechanism of its occurrence and development...
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The diffusion MRI signature index is highly correlated with immunohistochemical status and molecular subtype of invasive breast carcinoma
ObjectivesTo evaluate the relationship of the signature index (S-index), an advanced diffusion MRI marker, and the immunohistochemical (IHC) status,...
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Prognostic value of Ki-67 index in primary intracranial tumors of infants
ObjectivePrimary intracranial tumors are rare tumors in infants. They differ from those found in other pediatric age groups in terms of clinical...
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Inhibition of NUCB2 suppresses the proliferation, migration, and invasion of rheumatoid arthritis synovial fibroblasts from patients with rheumatoid arthritis in vitro
Rheumatoid arthritis (RA) is an autoimmune polyarthritis in which synovial fibroblasts (SF) play a major role in cartilage and bone destruction...
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Predictive effect of the systemic inflammation response index (SIRI) on the efficacy and prognosis of neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer
BackgroundInflammation is a part of tumours, and inflammatory cells can affect the proliferation, invasion, and development of tumour cells. An...
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KLF11 is an independent negative prognostic factor for breast cancer from a cohort study and induces proliferation and inhibits apoptosis in vitro
BackgroundThe therapy concepts that target several members of krüppel like factor (KLF) family have been achieved in breast cancer (BC). However, the...
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Prognostic marker C3AR1 is associated with ovarian cancer cell proliferation and immunosuppression in the tumor microenvironment
BackgroundC3AR1 was reported in driving tumor immunity in multiple cancers. However, its roles in ovarian cancer remain unclear. This study aims to...
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Correlation between bone density, bone metabolism markers with lipid metabolism markers and body mass index
PurposeWe aimed to explore the relationship between bone mineral density (BMD), bone metabolism markers, and blood lipid-related indicators, body...
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Effects of CpG sites methylation modification of HPV16 integration essential gene on the proliferation of cervical cancer cells
PurposeThe mechanism of methylation of HPV CpG sites in the occurrence and prognosis of cervical carcinogenesis remains unclear. We investigated the...