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In-silico computational approaches to study microbiota impacts on diseases and pharmacotherapy
Microorganisms have been linked to a variety of critical human disease, thanks to advances in sequencing technology and microbiology. The growing...
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A spatial obesity risk score for describing the obesogenic environment using kernel density estimation: development and parameter variation
BackgroundOverweight and obesity are severe public health problems worldwide. Obesity can lead to chronic diseases such as type 2 diabetes mellitus....
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Sensor-based fall risk assessment in older adults with or without cognitive impairment: a systematic review
BackgroundHigher age and cognitive impairment are associated with a higher risk of falling. Wearable sensor technology may be useful in objectively...
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Functional respiratory imaging in relation to classical outcome measures in cystic fibrosis: a cross-sectional study
BackgroundFunctional Respiratory Imaging (FRI) combines HRCT scans with computational fluid dynamics to provide objective and quantitative...
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Gait video-based prediction of unified Parkinson’s disease rating scale score: a retrospective study
BackgroundThe diagnosis of Parkinson’s disease (PD) and evaluation of its symptoms require in-person clinical examination. Remote evaluation of PD...
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Migration integration policies as social determinants of health for highly educated immigrants in the United States
Highly educated immigrants are part of the growing population of immigrants who are impacted by the increasingly hostile migration policies in the...
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Gait Patterns and Mood in Everyday Life: A Comparison Between Depressed Patients and Non-depressed Controls
BackgroundPrevious laboratory findings suggest deviant gait characteristics in depressed individuals (i.e., reduced walking speed and vertical...
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Modeling of Survival and Frequency of Cardiovascular-Related Hospitalization in Patients with Transthyretin Amyloid Cardiomyopathy Treated with Tafamidis
IntroductionATTR-ACT (Tafamidis in Transthyretin Cardiomyopathy Clinical Trial) demonstrated the efficacy and safety of tafamidis in transthyretin...
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Smartphones for musculoskeletal research – hype or hope? Lessons from a decennium of mHealth studies
BackgroundSmartphones provide opportunities for musculoskeletal research: they are integrated in participants’ daily lives and can be used to collect...
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Modeling multiple sclerosis using mobile and wearable sensor data
Multiple sclerosis (MS) is a neurological disease of the central nervous system that is the leading cause of non-traumatic disability in young...
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Effectiveness of the Elos 2.0 Program, a Classroom Good Behavior Game Version in Brazil
The Good Behavior Game (GBG) is a universal classroom behavior management method to reduce disruptive problems. This study aimed to evaluate the...
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Quality over quantity: powering neuroimaging samples in psychiatry
Neuroimaging has been widely adopted in psychiatric research, with hopes that these non-invasive methods will provide important clues to the...
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Growth pattern trajectories in boys with Duchenne muscular dystrophy
ObjectivesThe objective of this study is to analyse retrospective, observational, longitudinal growth (weight, height and BMI) data in ambulatory...
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The association between walking pace and hand grip strength with the risk of chronic obstructive pulmonary disease: a bidirectional Mendelian randomization study
BackgroundChronic Obstructive Pulmonary Disease (COPD) currently ranks as the third leading cause of mortality worldwide, imposing substantial...
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Timed up and go test predicts mortality in older adults in Peru: a population-based cohort study
BackgroundWhile there is evidence about stablished risk factors (e.g., raised blood pressure) and higher mortality risk in older population, less has...
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Magnetic resonance image segmentation of the compressed spinal cord in patients with degenerative cervical myelopathy using convolutional neural networks
PurposeSpinal cord segmentation is the first step in atlas-based spinal cord image analysis, but segmentation of compressed spinal cords from...
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Diagnostic accuracy of regadenoson stress echocardiography: concordance with gated-spect myocardial perfusion imaging
Regadenoson Stress Echocardiography (RSE) can detect myocardial ischemia, and its diagnostic accuracy should be evaluated. We sought to investigate...
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Analysis of risk factors for contralateral symptomatic foraminal stenosis after unilateral transforaminal lumbar interbody fusion
PurposeTo analyze the risk factors of contralateral symptomatic foraminal stenosis (FS) after unilateral transforaminal lumbar interbody fusion...
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Mediators of measurement-based care implementation in community mental health settings: results from a mixed-methods evaluation
BackgroundTailored implementation approaches are touted as superior to standardized ones with the reasoning that tailored approaches afford...
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Responding to human trafficking among refugees: prevalence and test accuracy of a modified version of the adult human trafficking screening tool
BackgroundHuman trafficking is a human rights violation and urgent public health challenge. It involves the exploitation of a person by means of...