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Signaling pathways and targeted therapies in lung squamous cell carcinoma: mechanisms and clinical trials
Lung cancer is the leading cause of cancer-related death across the world. Unlike lung adenocarcinoma, patients with lung squamous cell carcinoma...
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Basaloid Squamous Cell Carcinoma Cervix: A Case Report
Basaloid squamous cell carcinoma (BSCC) is a very rare but aggressive subtype of squamous cervical cancer. BSCC usually arises from hypo pharynx,...
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Pyroptosis-related long-noncoding RNA signature predicting survival and immunotherapy efficacy in patients with lung squamous cell carcinoma
Pyroptosis-related long-noncoding RNAs (PRlncRNAs) play an important role in cancer progression. However, their role in lung squamous cell carcinoma...
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Proposal of a grading system for squamous cell carcinoma of the lung — the prognostic importance of tumour budding, single cell invasion, and nuclear diameter
The prognostic markers of lung squamous cell carcinoma (LSCC) are less investigated. The aim of our study was to evaluate tumour budding (TB),...
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Acantholytic Squamous Cell Carcinoma: a Diagnostic Pitfall on Cytology
Acantholytic squamous cell carcinoma is an infrequent subtype of squamous cell carcinoma. This tumour variant being rare in itself has been rarely...
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Primary pulmonary hyalinizing clear cell carcinoma with vocal-cord squamous cell carcinoma: a case report with systematic review
BackgroundPrimary pulmonary hyalinizing clear cell carcinoma (HCCC) is a low-grade salivary gland-type carcinoma. Until now, 23 cases of pulmonary...
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FOXP3 expression in esophageal squamous cell carcinoma
ObjectiveInvestigating the impact of FOXP3 (transcription factor forkhead box P3) expression on the biological behavior of esophageal squamous cell...
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TET2 Is Downregulated in Early Esophageal Squamous Cell Carcinoma and Promotes Esophageal Squamous Cell Malignant Behaviors
ObjectiveTo explore the expression of the ten eleven translocation (TET) 2 protein in early esophageal squamous cell carcinoma (EESCC), precancerous...
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Survival Outcomes of Non-squamous Cell Carcinoma and Rare Squamous Cell Carcinoma Variants of the Larynx
The literature focuses primarily on laryngeal differentiated squamous cell carcinoma (SCC), and only a limited number of studies have evaluated the...
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Neuroendocrine differentiation distinguishes basaloid variant of lung squamous cell carcinoma
BackgroundNeuroendocrine (NE) differentiation is widely studied in non-small cell lung carcinomas (NSCLC) however, its significance remains unclear...
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Population-based high-dimensional analyses identify multiple intrinsic characters for cancer vaccines against lung squamous cell carcinoma
In lung squamous cell carcinoma (LUSC), current cancer vaccines show promising effects, despite a lack of benefit for a large number of patients. We...
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Long-term survival after pulmonary metastasectomy in patients with esophageal squamous cell carcinoma with lung metastasis
ObjectivesEsophageal squamous cell carcinoma with pulmonary metastasis has a poor prognosis, and the only treatment modality is systemic therapy such...
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ZEB1-activated Notch1 promotes circulating tumor cell migration and invasion in lung squamous cell carcinoma
BackgroundLung squamous cell carcinoma (LUSC) is recognized as the major subtypes of non-small cell lung cancer (NSCLC). Circulating tumor cells...
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Establishment of a prognosis prediction model for lung squamous cell carcinoma related to PET/CT: basing on immunogenic cell death-related lncRNA
BackgroundImmunogenic cell death (ICD) stimulates adaptive immunity and holds significant promise in cancer therapy. Nevertheless, the influence of...
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Breast Implant Capsule-Associated Squamous Cell Carcinoma: A Systematic Review and Case Presentation
AbstractBreast implant capsule-associated squamous cell carcinoma is exceedingly rare, with only eleven previously published cases. The present study...
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The relationship of airflow limitation with lung squamous cell carcinoma: evidence from mendelian randomization analysis
BackgroundObservational studies showed associations between smoking, and airflow limitation, with lung squamous cell carcinoma (LUSC). However, the...
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CISD2 promotes lung squamous carcinoma cell migration and invasion via the TGF-β1-induced Smad2/3 signaling pathway
BackgroundAlthough aberrant expression of CDGSH iron sulfur domain 2 (CISD2) contributes to the tumorigenesis and progression of numerous human...
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Necitumumab plus gemcitabine and cisplatin in previously treated lung squamous cell carcinoma
Background: The efficacy and safety of the anti-EGFR antibody necitumumab combined with gemcitabine and cisplatin (N + GC) in the first-line...
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Duodenal diverticulum metastasis from pulmonary squamous cell carcinoma diagnosed by EUS-FNA
A 76-year-old male with pulmonary squamous cell carcinoma achieved complete response by chemoradiotherapy and subsequent systemic chemotherapy....
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Morphometric analysis of nuclear shape irregularity as a novel predictor of programmed death-ligand 1 expression in lung squamous cell carcinoma
Immune checkpoint inhibitor (ICI) therapy has been established as one of the key treatment strategies for lung squamous cell carcinoma (LUSQ). The...