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  1. A deep learning-driven discovery of berberine derivatives as novel antibacterial against multidrug-resistant Helicobacter pylori

    Helicobacter pylori ( H. pylori ) is currently recognized as the primary carcinogenic pathogen associated with gastric tumorigenesis, and its high...

    **xi Guo, **aosa Zhao, ... Jiandong Jiang in Signal Transduction and Targeted Therapy
    Article Open access 08 July 2024
  2. The role of anti-citrullinated protein antibody in pathogenesis of RA

    Rheumatoid arthritis (RA) is a common autoimmune rheumatic disease that causes chronic synovitis, bone erosion, and joint destruction. The...

    Hang Ma, Xu Liang, ... Tian-Fang Li in Clinical and Experimental Medicine
    Article Open access 08 July 2024
  3. Prospective investigation of amino acid transport and PSMA-targeted positron emission tomography for metastatic lobular breast carcinoma

    Purpose

    To explore the feasibility of imaging amino-acid transport and PSMA molecular pathways in the detection of metastatic breast invasive lobular...

    Aliza Mushtaq, Ismaheel O. Lawal, ... David M. Schuster in European Journal of Nuclear Medicine and Molecular Imaging
    Article 08 July 2024
  4. Chemotherapy’s effects on autophagy in the treatment of Hodgkin’s lymphoma: a sco** review

    Background

    Classical Hodgkin Lymphomas (HL) are a unique malignant growth with an excellent initial prognosis. However, 10–30% of patients will still...

    Roro Wahyudianingsih, Ardo Sanjaya, ... Bethy Suryawathy Hernowo in Discover Oncology
    Article Open access 08 July 2024
  5. [18F]-D3FSP β-amyloid PET imaging in older adults and alzheimer’s disease

    Purpose

    [ 18 F]-D3FSP is a new β-amyloid (Aβ) PET imaging tracer designed to decrease nonspecific signals in the brain by reducing the formation of the...

    Anqi Li, Ruiyue Zhao, ... Tengfei Guo in European Journal of Nuclear Medicine and Molecular Imaging
    Article 08 July 2024
  6. Hypothyroidism after hemithyroidectomy: a systematic review and meta-analysis

    Background

    The incidence of hypothyroidism following hemithyroidectomy and risk factors associated with its occurrence are not completely understood....

    Dominic Cooper, Rajneesh Kaur, ... Senarath Edirimanne in Thyroid Research
    Article Open access 08 July 2024
  7. Impact of DAA Treatment for HCV on Hepatocellular Carcinoma in a Predominately African American Population

    Purpose

    This study tested the hypothesis that our predominately AA medical center population would demonstrate a decline in HCV-driven HCC diagnosis...

    Mohamad I. Itani, Bassem Farah, ... Milton Mutchnick in Journal of Gastrointestinal Cancer
    Article 08 July 2024
  8. Comparison of synthesized and acquired high b-value diffusion-weighted MRI for detection of prostate cancer

    Background

    High b -value diffusion-weighted images (DWI) are used for detection of clinically significant prostate cancer (csPCa). This study...

    Karoline Kallis, Christopher C. Conlin, ... Tyler M. Seibert in Cancer Imaging
    Article Open access 08 July 2024
  9. Sublingual sufentanil for patient-controlled analgesia during labor induction for pregnancy termination: an effective and well-tolerated approach

    Background

    Effective pain management during labor induction for pregnancy termination is essential. However, to date, no effective treatment has been...

    Giulia Fierro, Barbara Milan, ... Ferdinando Luca Lorini in Journal of Anesthesia, Analgesia and Critical Care
    Article Open access 08 July 2024
  10. Multi-omics differences in the bone marrow between essential thrombocythemia and prefibrotic primary myelofibrosis

    Essential thrombocythemia (ET) and prefibrotic primary myelofibrosis (pre-PMF) are Philadelphia chromosome-negative myeloproliferative neoplasms....

    Anqi Zhang, Ting Sun, ... Lei Zhang in Clinical and Experimental Medicine
    Article Open access 08 July 2024
  11. Robotic Left Pancreatectomy with Perirenal Tissue Excision and Left Adrenalectomy (Posterior Ramps) for Pancreatic Ductal Adenocarcinoma Abutting the Adrenal Gland

    Background

    Radical antegrade modular pancreato-splenectomy (RAMPS) has been largely described in left-sided pancreatic cancers.1.J...

    Fabio Giannone, Oronzo Ligurgo, ... Patrick Pessaux in Annals of Surgical Oncology
    Article 07 July 2024
  12. Enhanced cancer cell proliferation and aggressive phenotype counterbalance in breast cancer with high BRCA1 gene expression

    Purpose

    While comprehensive research exists on the mutation of the DNA repair gene BRCA1 , limited information is available regarding the clinical...

    Kohei Chida, Masanori Oshi, ... Kazuaki Takabe in Breast Cancer Research and Treatment
    Article 07 July 2024
  13. Cholangiocarcinoma of the Middle Bile Duct: A Narrative Review

    Resectable cholangiocarcinoma (CCA) arising from the middle of the extrahepatic biliary tree has historically been classified as perihilar or distal...

    Elliott J. Yee, Ioannis A. Ziogas, ... Richard D. Schulick in Annals of Surgical Oncology
    Article 07 July 2024
  14. Endoscopic ultrasound-guided hepaticogastrostomy vs. antegrade metal stent placement kee** an access route in patients with malignant biliary obstruction

    Background

    Few studies have compared endoscopic ultrasound (EUS)-guided hepaticogastrostomy (HGS) with EUS-guided antegrade metal stent placement...

    Masahiro Itonaga, Reiko Ashida, ... Masayuki Kitano in International Journal of Clinical Oncology
    Article 07 July 2024
  15. Normal ovarian sizes on MRI in pediatric patients: a preliminary study

    Background

    Ovarian enlargement is one of several findings of pathology, including ovarian torsion. With increasing use of MRI for acute abdominal pain...

    Katherine N. Epstein, Andrew T. Trout, ... Rama S. Ayyala in Pediatric Radiology
    Article 06 July 2024
  16. Cost–utility analysis of a palliative care program in Colombia

    Background

    The economic assessment of health care models in palliative care promotes their global development. The purpose of the study is to assess...

    Luisa Rodríguez-Campos, Paul Andres Rodriguez-Lesmes, ... Abel E. González-Vélez in BMC Palliative Care
    Article Open access 06 July 2024
  17. DNMT3A-R882: a mutation with many paradoxes

    Understanding the underlying mechanism of acute myeloid leukemia (AML) has led to the discovery of novel biomarkers to help predict, treat and...

    Pourya Arbab Jafari, Ramin Bagheri, ... Sajad Goudarzi in Annals of Hematology
    Article 06 July 2024
  18. Deciphering glutamine metabolism patterns for malignancy and tumor microenvironment in clear cell renal cell carcinoma

    Clear cell renal cell carcinoma (ccRCC) is the most common subtype of kidney cancer characterized by metabolic reprogramming. Glutamine metabolism is...

    Gengrun Wu, Teng Li, ... Hailiang Zhang in Clinical and Experimental Medicine
    Article Open access 06 July 2024
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