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Similar genetic profile in early and late stage urothelial tract cancer
IntroductionUrothelial tract cancer (UTC) ranks as the tenth most prevalent cancer and holds the seventh position in terms of mortality worldwide....
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Mitochondrial Adaptation in Skeletal Muscle: Impact of Obesity, Caloric Restriction, and Dietary Compounds
Purpose of ReviewThe global obesity epidemic has become a major public health concern, necessitating comprehensive research into its adverse effects...
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Mature B, T and NK-cell, plasma cell and histiocytic/dendritic cell neoplasms: classification according to the World Health Organization and International Consensus Classification
In 2022, two updated classification systems for lymphoid neoplasms were published by the World Health Organization (WHO Classification of...
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Heparin-induced thrombocytopenia with very high antibody titer is associated with slower platelet recovery and higher risk of thrombosis
Heparin-induced thrombocytopenia (HIT) is a prothrombotic disorder mediated by platelet-activating antibodies targeting platelet factor 4 (PF4) and...
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A cellular senescence-related signature for predicting prognosis, immunotherapy response, and candidate drugs in patients treated with transarterial chemoembolization (TACE)
BackgroundCellular senescence is essential to TME development, progression, and remodeling. Few studies have examined cellular senescence in HCC...
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Virtual Interviews in the Post-COVID-19 Emergency Era: Insights from the Gastroenterology Fellowship Applicants and Programs
BackgroundVirtual interviews are still recommended for fellowship applications, 3 years after the beginning of the COVID-19 pandemic. Improving...
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Safety of Endoscopy in Cirrhosis
BackgroundEndoscopic procedures are among the most commonly performed medical procedures and the serious adverse event rate is reported to be 1–3...
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Navigating the “First Gastroenterology Job” Search for American and International Medical Graduates
GI fellowships do not mandate curricula in career development. Often, fellows resort to peer mentorship for guidance. Fellows should recognize that...
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CD8-positive T-cell lymphoproliferative disorder of the uterus: a new subtype of indolent extranodal T-cell neoplasm?
A 51-year-old female with menorrhagia was found to have a cervical polyp. Polypectomy and endometrial curettage showed an atypical lymphoid...
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Spanish Society of Medical Oncology recommendations for comprehensive assessment and care of cancer survivors’ needs
This article reviews the contemporary and inclusive definition of cancer survivorship, including patients with and without disease who have completed...
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Efficacy and safety of tislelizumab plus bacillus-calmette guérin with or without chemotherapy as a bladder-sparing treatment for high-risk non-muscle-invasive bladder urothelial cancer: a real-world study
BackgroundDespite adequate transurethral resection of the bladder tumor (TURBT) followed by intravesical bacillus-calmette guérin (BCG), high-risk...
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Guidelines for holistic integrative management of pancreatic cancer
BackgroundPancreatic cancer ranks 10 th in the incidence rate of malignant tumors in male, and 12 th in female. Pancreatic cancer is the sixth leading...
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Endoscopic and exoscopic surgery for brain tumors
Nerves and blood vessels must be protected during brain tumor surgery, which has traditionally relied on microscopes. In the 2000s, endoscopes and...
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A prospective study of vitamin D, proinflammatory cytokines, and risk of fragility fractures in women on aromatase inhibitors for breast cancer
BackgroundVitamin D is critical to bone health by regulating intestinal absorption of calcium, whereas proinflammatory cytokines, including IL-1,...
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Hypothyroidism after hemithyroidectomy: a systematic review and meta-analysis
BackgroundThe incidence of hypothyroidism following hemithyroidectomy and risk factors associated with its occurrence are not completely understood....
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Impact of DAA Treatment for HCV on Hepatocellular Carcinoma in a Predominately African American Population
PurposeThis study tested the hypothesis that our predominately AA medical center population would demonstrate a decline in HCV-driven HCC diagnosis...
