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Preventing long-term disability in CIDP: the role of timely diagnosis and treatment monitoring in a multicenter CIDP cohort
BackgroundChronic inflammatory demyelinating polyneuropathy (CIDP) is an inflammatory disease affecting the peripheral nerves and the most frequent...
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Simplifying synthesis of the expanding glioblastoma literature: a topic modeling approach
PurposeOur study aims to discover the leading topics within glioblastoma (GB) research, and to examine if these topics have “hot” or “cold” trends....
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Momelotinib versus Continued Ruxolitinib or Best Available Therapy in JAK Inhibitor-Experienced Patients with Myelofibrosis and Anemia: Subgroup Analysis of SIMPLIFY-2
IntroductionSome Janus kinase (JAK) inhibitors such as ruxolitinib and fedratinib do not address and may worsen anemia in patients with...
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Radiomics model based on dual-energy CT can determine the source of thrombus in strokes with middle cerebral artery occlusion
PurposeTo develop thrombus radiomics models based on dual-energy CT (DECT) for predicting etiologic cause of stroke.
MethodsWe retrospectively...
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Magnetic Seizure Therapy in Management of Depression: A Narrative Review
Purpose of ReviewThis review aims to discuss historical aspects, mechanism of action, safety and efficacy, response predictors, and Magnetic Seizure...
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Diacerein mitigates endocrine and cardio-metabolic disruptions in experimental PCOS mice model by modulating AdipoR1/ PON 1
BackgroundThis study aimed to explore the impact of Diacerein (DIC) on endocrine and cardio-metabolic changes in polycystic ovarian syndrome (PCOS)...
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Partial coil embolization before surgical clip** of ruptured intracranial aneurysms
ObjectiveIntraoperative rupture (IOR) is the most common adverse event encountered during surgical clip obliteration of ruptured intracranial...
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Spinal dementia: Don’t miss it, it’s treatable
Background & purposeAround 5% of dementia patients have a treatable cause. To estimate the prevalence of two rare diseases, in which the treatable...
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A clinically compatible in vitro drug-screening platform identifies therapeutic vulnerabilities in primary cultures of brain metastases
PurposeBrain metastases represent the most common intracranial tumors in adults and are associated with a poor prognosis. We used a personalized in...
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Intraoperative MRI without an intraoperative MRI suite: a workflow for glial tumor surgery
BackgroundIntraoperative MRI (iMRI) has emerged as a useful tool in glioma surgery to safely improve the extent of resection. However, iMRI requires...
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Obstetric cholestasis and its impact on the maternal outcome
AimTo evaluate the association of GDM and pre-eclampsia in women with obstetric cholestasis.
Materials and methodsPregnant women with > 28 weeks...
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Immune responses to oligomeric α-synuclein in Parkinson’s disease peripheral blood mononuclear cells
Parkinson’s disease displays clinical heterogeneity, presenting with motor and non-motor symptoms. Heterogeneous phenotypes, named brain-first and...
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Assessment of the importance of sleep quality and the effects of deprivation on Sudanese healthcare professionals amidst conflict in Sudan
BackgroundQuality sleep is vital for well-being, especially for healthcare workers facing high risks of fatigue and burnout. Sleep deprivation...
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Neurological and Psychiatric Clinical Manifestations of Sjögren Syndrome
Purpose of ReviewSjögren Syndrome is a systemic autoimmune disorder that presents mainly with sicca symptoms, but frequently affects other body...
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Review on the role of hypothalamic astrocytes in the neuroendocrine control of metabolism
Astrocytes are the most numerous type of glial cells found in the nervous system. They regulate energy homeostasis in collaboration with the neuronal...
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Analysis of the impact of a university distance learning course on digitalization in medicine on students and healthcare professionals
PurposeThe public medical universities in Austria (educating 11,000 students) developed a joint public distance learning series in which clinicians...
