Search
Search Results
-
Detection and characterization of autoreactive memory stem T-cells in children with acute immune thrombocytopenia
Primary immune thrombocytopenia (ITP) is an acquired autoimmune disorder characterized by an isolated decrease in platelets below 100 × 10 9 /l after...
-
Evaluating [225Ac]Ac-FAPI-46 for the treatment of soft-tissue sarcoma in mice
PurposeFibroblast Activation Protein (FAP) is an emerging theranostic target that is highly expressed on cancer-associated fibroblasts and on certain...
-
Efficacy and Safety of Salvage-line Nivolumab Monotherapy for Advanced Esophageal Squamous Cell Carcinoma: Comparison of 240 mg Versus 480 mg Doses
BackgroundNivolumab monotherapy is the standard second-line treatment for advanced esophageal squamous cell carcinoma (ESCC) after failure of...
-
-
Interrelationship between thyroid hormones and reduced renal function, a review article
BackgroundUnderstanding the relationship of thyroid hormones with the development of chronic kidney disease (CKD) has important clinical implications...
-
SHR-A1811 (antibody-drug conjugate) in advanced HER2-mutant non-small cell lung cancer: a multicenter, open-label, phase 1/2 study
A dose-escalation and expansion, phase 1/2 study (ClinicalTrials.gov, NCT04818333) was conducted to assess the novel antibody-drug conjugate...
-
Map** alternative splicing events in colorectal cancer
Although aberrant splicing events of genes are closely related to the development and progression of colorectal cancer (CRC), the map** of abnormal...
-
Preclinical SPECT and PET: Joint EANM and ESMI procedure guideline for implementing an efficient quality control programme
The aim of this guideline is to provide recommendations for the implementation of an effective and efficient quality control (QC) programme for SPECT...
-
Cardiovascular events in CML patients treated with Nilotinib: validation of the HFA-ICOS baseline risk score
BackgroundThe therapeutic landscape of chronic myeloid leukaemia (CML) has been transformed by tyrosine kinase inhibitors (TKI). Nilotinib, showed...
-
Die Psyche atmet mit
BackgroundIn addition to significant physical limitations, individuals with interstitial lung diseases (ILD) often experience reduced quality of life...
-
The multifaceted role of PCSK9 in cancer pathogenesis, tumor immunity, and immunotherapy
Proprotein convertase subtilisin/kexin type 9 (PCSK9), a well-known regulator of cholesterol metabolism and cardiovascular diseases, has recently...
-
-
ACTH-producing adrenocortical carcinoma: an exceedingly rare diagnosis
BackgroundAdrenocortical carcinoma is a very rare endocrinopathy that has a poor prognosis and is frequently associated with ACTH-independent...
-
Sex ratio at birth across 100 years in Sweden and risk of cardiovascular disease and all-cause mortality – a national register study
The human sex ratio at birth (SRB) undergoes temporary changes around a mean proportion of 0.51 male births. SRB has been well studied for...
-
Impact on Glycemia Risk Index and other metrics in type 1 adult patients switching to Advanced Hybrid Closed-Loop systems: a one-year real-life experience
BackgroundAdvanced Hybrid Closed-Loop system (AHCL) has profoundly changed type 1 diabetes therapy. This study primarily aimed to assess the impact...
-
-
Efficacy and safety of rechallenge [177Lu]Lu-PSMA-617 RLT after initial partial remission in patients with mCRPC: evaluation of a prospective registry (REALITY study)
AimRechallenge of [ 177 Lu]Lu-PSMA-617 radioligand therapy (RLT) was proposed for patients who initially responded to PSMA-RLT experiencing partial...