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  1. Radiomics combined with clinical and MRI features may provide preoperative evaluation of suboptimal debulking surgery for serous ovarian carcinoma

    Purpose

    To develop and validate a model for predicting suboptimal debulking surgery (SDS) of serous ovarian carcinoma (SOC) using radiomics method,...

    Li Liu, Wenfei Zhang, ... Yongmei Li in Abdominal Radiology
    Article Open access 14 July 2024
  2. PIM1/NF-κB/CCL2 blockade enhances anti-PD-1 therapy response by modulating macrophage infiltration and polarization in tumor microenvironment of NSCLC

    Elevated infiltration of tumor-associated macrophages (TAMs) drives tumor progression and correlates with poor prognosis for various tumor types. Our...

    **uqiong Chen, **g Zhou, ... Richeng Jiang in Oncogene
    Article 14 July 2024
  3. PHF6 suppresses self-renewal of leukemic stem cells in AML

    Acute myeloid leukemia is characterized by uncontrolled proliferation of self-renewing myeloid progenitors accompanied by a differentiation arrest....

    Sapana S. Jalnapurkar, Aishwarya S. Pawar, ... Vikram R. Paralkar in Leukemia
    Article Open access 14 July 2024
  4. Outcomes of patients undergoing third hematopoietic cell transplantation for hematologic malignancies

    With advancements in novel therapeutics, it is unclear whether third hematopoietic cell transplantation (HCT3) has a place in the treatment of...

    Emily R. Cox, Corinne Summers, ... Monica S. Thakar in Annals of Hematology
    Article 14 July 2024
  5. Trametinib for a child with refractory Rosai–Dorfman–Destombes disease harboring a novel somatic mutation in MAP2K1

    Rosai–Dorfman–Destombes disease (RDD) is a rare histiocytosis characterized by accumulation of S100 + , CD68 + , and CD1a- histiocytes, with...

    Yuichi Taneyama, Akira Morimoto, ... Sana Yokoi in International Journal of Hematology
    Article 14 July 2024
  6. Death anxiety among caregivers of patients with advanced cancer: a cross-sectional survey

    Purpose

    This study aimed to investigate death anxiety (DA) in caregivers of patients with advanced cancer and identify associated factors in the...

    Li Ying, Duan Yuyu, ... Zhou Zhihuan in Supportive Care in Cancer
    Article 13 July 2024
  7. Association of oral mucositis induced by anthracycline-cyclophosphamide and subsequent docetaxel treatment for perioperative breast cancer

    Purpose

    Anthracycline-cyclophosphamide followed by docetaxel-containing chemotherapy is effective for perioperative breast cancer treatment. However,...

    Yoshitaka Saito, Yoh Takekuma, ... Mitsuru Sugawara in Supportive Care in Cancer
    Article 13 July 2024
  8. Peripheral blood immune parameters, response, and adverse events after neoadjuvant chemotherapy plus durvalumab in early-stage triple-negative breast cancer

    Purpose

    We evaluated T- and B-cell receptor (TCR and BCR) repertoire diversity and 38 serum cytokines in pre- and post-treatment peripheral blood of...

    Julia Foldi, Kim R. M. Blenman, ... Lajos Pusztai in Breast Cancer Research and Treatment
    Article 13 July 2024
  9. Risk factors associated with radiological and clinical recurrences after laparoscopic repair of large hiatal hernia with TiO2Mesh™ reinforcement

    Introduction

    Laparoscopic repair of large para-esophageal hiatal hernias (LPHH) remains controversial. Several meta-analyses suggest hiatus...

    Pablo Priego, Luz Divina Juez, ... José María Fernández-Cebrián in Hernia
    Article 13 July 2024
  10. Safety and Efficacy of Covered Self-Expandable Metallic Stent for Choledochojejunal Anastomotic Stricture: A Multi-Center Retrospective Cohort Study

    Background

    Benign choledochojejunal anastomotic stricture (CJS) is a complication of pancreaticoduodenectomy and choledochojejunostomy. Typically...

    Yuhei Iwasa, Takuji Iwashita, ... Masahito Shimizu in Digestive Diseases and Sciences
    Article 13 July 2024
  11. Hyponatremia Is Associated with Mortality in Acute Pancreatitis Patients

    Background

    Disorders of serum sodium are common among general patients and are associated with poor outcomes. The prognostic value of serum sodium...

    Liqing Song, Wen Tang, ... Ying Xu in Digestive Diseases and Sciences
    Article 13 July 2024
  12. On-treatment decline in MELD score predicts one-month transplant-free survival in rodenticidal hepatotoxicity patients treated with low-volume plasma exchange

    Background and Aim

    Plasma exchange (PLEX) improves survival in patients with rodenticidal hepatotoxicity. However, predictors of treatment response...

    Vijay Alexander, Gayathiri Kaduvetti Chellaiya, ... Ashish Goel in Indian Journal of Gastroenterology
    Article 13 July 2024
  13. Deep learning model based on endoscopic images predicting treatment response in locally advanced rectal cancer undergo neoadjuvant chemoradiotherapy: a multicenter study

    Purpose

    Neoadjuvant chemoradiotherapy has been the standard practice for patients with locally advanced rectal cancer. However, the treatment response...

    Junhao Zhang, Ruiqing Liu, ... Yun Lu in Journal of Cancer Research and Clinical Oncology
    Article Open access 13 July 2024
  14. Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition

    SF3B1 mutations frequently occur in cancer yet lack targeted therapies. Clinical trials of XPO1 inhibitors, selinexor and eltanexor, in high-risk...

    Sana Chaudhry, Felipe Beckedorff, ... Justin Taylor in Leukemia
    Article Open access 13 July 2024
  15. BRAF-mutant mismatch repair deficient invasive colon cancer regressing to sessile serrated lesion

    A 69-year-old female was presented with a history of sigmoid colon cancer, uterine cancer, and intrahepatic carcinomas. After computed tomography...

    Kenshi Matsuno, Hideaki Miyamoto, ... Yasuhito Tanaka in Clinical Journal of Gastroenterology
    Article 13 July 2024
  16. An update to experimental and clinical aspects of tumor-associated macrophages in cancer development: hopes and pitfalls

    Tumor-associated macrophages (TAMs) represent one of the most abundant tumor-infiltrating stromal cells, and their normal function in tumor...

    Arash Salmaninejad, Sepideh Mehrpour Layeghi, ... Meysam Yousefi in Clinical and Experimental Medicine
    Article Open access 13 July 2024
  17. Longitudinal Increases in Time to Surgery for Patients with Breast Cancer: A National Cohort Study

    Background

    Longer time to surgery (TTS) is associated with worse survival in patients with breast cancer. Whether this association has encouraged more...

    Gabriella N. Tortorello, Neha Shafique, ... Giorgos C. Karakousis in Annals of Surgical Oncology
    Article Open access 13 July 2024
  18. Efficacy and safety of glucocorticoids in the treatment of COVID-19: a systematic review and meta-analysis of RCTs

    In the realm of acute respiratory infections, coronavirus disease-19 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2...

    **angrong Ye, Ye Li, ... Yifeng Luo in Clinical and Experimental Medicine
    Article Open access 13 July 2024
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