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Novel multifunctional bioactive glass incorporated alginate/poly(amidoamine) hydrogels with controlled drug release for cartilage tissue regeneration
Tissue engineering faces an intriguing challenge in creating biomaterials for cartilage repair. Within the category of biopolymeric scaffolds,...
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Preparation and characterization of a novel pH-sensitive pectin-grafted-poly (acrylic acid-co-itaconic acid)/MWCNTs-COOH hydrogel composite for adsorption and controlled release of diclofenac sodium
In the present study, a novel pH-sensitive hydrogel composite of pectin-grafted-poly (acrylic acid-co-itaconic acid)/MWCNTs-COOH was prepared by...
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Drug release behaviour and mechanism from unmodified and in situ modified bacterial cellulose
Bacterial cellulose (BC) is a suitable drug delivery carrier owing to the nanofibrous micro and mesoporous structure. One of the unique aspects is...
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Techniques to Fabricate Electrospun Nanofibers for Controlled Release of Drugs and Biomolecules
Electrospinning is a nanotechnology-based platform with great potential in tissue engineering and related biomedical applications. The high...
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In vitro and in vivo Research of Sustained Release ketotifen fumarate for Treatment of asthma
Ketotifen fumarate, a mast cell stabilizer, is frequently prescribed in low doses to manage chronic asthma of allergic origin. However, it shows...
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Benznidazole in vitro dissolution release from a pH-sensitive drug delivery system using Zif-8 as a carrier
Chagas disease is a neglected tropical disease caused by the flagellate protozoan Trypanosoma cruzi ( T. cruzi ). Endemic in underdeveloped and...
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Engineered Spindles of Little Molecules Around Electrospun Nanofibers for Biphasic Drug Release
Biphasic drug release is a popular advanced drug controlled release profile that has been drawing increasing attention from many fields. Electrospun...
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Metal–ligand-based thixotropic self-healing poly (vinyl alcohol) metallohydrogels: Their application in pH-responsive drug release and selective adsorption of dyes
AbstractThis work reports in situ fabrication of biocompatible metallohydrogels composed of polyvinyl alcohol (PVA) polymer crosslinked via...
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In-Situ γ-γ′ Lattice Parameter Evolution and Tertiary Burst Phenomena During Controlled Cooling of Commercial PM Nickel-Base Superalloys
The γ and γ ′ lattice parameter evolution of two commercial powder metallurgy (PM) nickel-base superalloys, ME3 and Rene’88DT, during cooling from...
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Hollow mesoporous silica nanoparticles for co-delivery of hydrophobic and hydrophilic molecules: mechanism of drug loading and release
The objective of this study was to investigate the loading capacity and release profiles of curcumin (CUR), as a hydrophobic drug molecule, and...
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Polyethylenimine-functionalized fibroin nanoparticles as a potential oral delivery system for BCS class-IV drugs, a case study of furosemide
Limited studies have exploited the silk fibroin potential as an oral drug delivery system. Herein, this study developed and characterized the...
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Electrospun dimethyloxallylglycine sustained release scaffold for promoting the migration and multidirectional differentiation of stem cells from the apical papilla
Dental pulpitis, a common dental disease, poses a significant challenge for modern dentistry because of the intricate framework and limited...
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Hollow structures as drug carriers: Recognition, response, and release
Hollow structures have demonstrated great potential in drug delivery owing to their privileged structure, such as high surface-to-volume ratio, low...
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Nanogels as controlled drug release systems for Coenzyme Q10 and Resveratrol for cosmetic application
Polymeric nanogels have been widely used as drug carrier systems due to their high drug loading capacity and an improved solubility of hydrophobic...
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Biodegradable and injectable poly(vinyl alcohol) microspheres in silk sericin-based hydrogel for the controlled release of antimicrobials: application to deep full-thickness burn wound healing
Deep full-thickness burn wounds are prone to multi-drug resistant (MDR) infections following injury, which extends the healing time. Thus, providing...
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Flurbiprofen microneedle patches for the management of acute postoperative pain
Acute postoperative pain is commonly treated with flurbiprofen (FBP), but conventional delivery methods are suboptimal. This study prepared a new...
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In vitro study of fluoride release of calcium fluoride–porcine bone–derived hydroxyapatite composite
Fluoride-releasing materials are helpful in the remineralization of enamel in teeth that erodes due to caries. These materials range from glass...
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Multi-step cefazolin sodium release from bioactive TiO2 nanotubes: Surface and polymer coverage effects
AbstractBacterial implant-related infections have been pointed out as the leading cause of metal implant failure. Recently, nanotexturization of...
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Titania nanotube arrays as nanobiomatrix interfaces for localized biomolecules delivery to human neuroblastoma SH-SY5Y cells
Titania nanotube arrays (TNA) surface has become a promising nano-surface technology for medical implant application. However, its application in...
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Constructing an on-demand drug release system composed of thermosensitive PPP hydrogel and drug-laden alginate/graphene microspheres to treat tumorous defect
In this study, we prepared a drug-laden graphene-incorporated calcium alginate (GCA) microspheres, which were then blended with the typically...
