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Effects of Chemical Fixatives on Kinetic Measurements of Biomolecular Interaction on Cell Membrane
Understanding the interaction between ligands and membrane proteins is important for drug design and optimization. Although investigation using live...
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Effects of Progesterone and Selective Ligands of Membrane Progesterone Receptors in HepG2 Cells of Human Hepatocellular Carcinoma
AbstractProgesterone exerts multiple effects in different tissues through nuclear receptors (nPRs) and through membrane receptors (mPRs) of...
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Effects of a human amniotic membrane extract on ARPE-19 cells
BackgroundHuman Amniotic Membrane (hAM) is endowed with several biological activities and might be considered an optimal tool in surgical treatment...
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Tethering proteins in membrane traffic
In eukaryotic cells, protein secretion and the transport of materials between membrane-bounded organelles require efficient and accurate delivery of...
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Cooperativity in regulation of membrane protein function: phenomenological analysis of the effects of pH and phospholipids
Interaction between membrane proteins and ligands plays a key role in governing a wide spectrum of cellular processes. These interactions can provide...
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Effects of monolauroyl-galactosylglycerol on membrane fatty acids and properties of Bacillus cereus
AbstractThe purpose of this study was to provide new ideas for the antibacterial mechanism of monolauroyl-galactosylglycerol (MLGG) from the...
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Effects of membrane cholesterol-targeting chemicals on skeletal muscle contractions evoked by direct and indirect stimulation
Cholesterol is one of the major components of plasma membrane, where its distribution is nonhomogeneous and it participates in lipid raft formation....
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Comparison of the effects of preservation methods on structural, biological, and mechanical properties of the human amniotic membrane for medical applications
Amniotic membrane (AM), the innermost layer of the placenta, is an exceptionally effective biomaterial with divers applications in clinical medicine....
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Membrane lipids drive formation of KRAS4b-RAF1 RBDCRD nanoclusters on the membrane
The oncogene RAS, extensively studied for decades, presents persistent gaps in understanding, hindering the development of effective therapeutic...
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Diet effects on longevity, heat tolerance, lipid peroxidation and mitochondrial membrane potential in Daphnia
The dietary supply of polyunsaturated fatty acids (PUFA) crucially affects animals’ performance at different temperatures. However, the underlying...
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Defining Membrane Protein Localization by Isopycnic Density Gradients
Bacterial membrane proteins account for around one-third of the proteome in many species and can represent much more than half of the mass of the...
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Protopanaxadiol Targeting Membrane Induces HepG2 Cell Apoptosis Via Raft-like Formation and Tubulation Disruption
Protopanaxadiol (PPD), which has a molecular structure similar to cholesterol, is a potent anticancer agent that has been proposed to target the...
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Biophysical Characterization of Membrane Proteins
Membrane proteins are responsible for a large variety of tasks in organisms and of particular interesting as drug targets. At the same time, they are...
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An important detail that is still not clear in amniotic membrane applications: How do we store the amniotic membrane best?
The use of fresh amniotic membrane (AM) is not a viable option, as it has many disadvantages. Preserving the AM reduces the risk of cross-infection...
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Molecular mechanisms in clathrin-mediated membrane budding
Clathrin-coated vesicles (CCVs) form at the plasma membrane where they select cargo for endocytic entry into cells. CCVs also form at the trans-Golgi...
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The impact of powdered activated carbon types on membrane anti-fouling mechanism in membrane bioreactors
AbstractDosing powdered activated carbon (PAC) has been proven to be an economical and effective method to mitigate membrane fouling. However, the...
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Electrostatic switch mechanisms of membrane protein trafficking and regulation
Lipid-protein interactions are normally classified as either specific or general. Specific interactions refer to lipid binding to specific binding...
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Effects of Gelsemium elegans extract on the red fire ant: disruption of peritrophic membrane integrity and alteration of gut microbial diversity, composition, and function
Gelsemium elegans Benth. ( Loganiaceae ), also known as heartbreak herb, can be used in the manufacture of herbal medicines. Insecticidal activity has...
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Generation of nanoscopic membrane curvature for membrane trafficking
Curved membranes are key features of intracellular organelles, and their generation involves dynamic protein complexes. Here we describe the...
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The effects of different thermal and chemical stresses on release of outer membrane vesicles (OMVs) by ClearColi™
The highly immunogenic properties of outer membrane vesicles (OMVs), small spherical nanoparticles commonly released by Gram-negative bacteria, led...
