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Systematic comparison of sequencing-based spatial transcriptomic methods
Recent developments of sequencing-based spatial transcriptomics (sST) have catalyzed important advancements by facilitating transcriptome-scale...
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Recovery of missing single-cell RNA-sequencing data with optimized transcriptomic references
Single-cell RNA-sequencing (scRNA-seq) is an indispensable tool for characterizing cellular diversity and generating hypotheses throughout biology....
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Building Phylogenies from Transcriptomic Data
Transcriptomic data (obtained from RNA sequencing) has become a very powerful source of information to reconstruct the evolutionary relationships...
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Integrating host transcriptomic signatures for distinguishing autoimmune encephalitis in cerebrospinal fluid by metagenomic sequencing
BackgroundThe early accurate diagnoses for autoimmune encephalitis (AE) and infectious encephalitis (IE) are essential since the treatments for them...
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Biclustering for Epi-Transcriptomic Co-functional Analysis
Dynamic and reversible N6-methyladenosine (m6A) modifications are associated with many essential cellular functions as well as physiological and...
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Advances in the Genomic and Transcriptomic Sequencing of North American Pines
Genetic and evolutionary questions are being addressed in pines using a host of high-throughput sequencing strategies, including whole-genome...
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Purification by STA-PUT Technique of Male Germ Cells from Single Mouse and RNA-Extraction for Transcriptomic Analysis
Transcriptomic analyses of germ cells at different stages of differentiation have shed light on the transcriptional and post-transcriptional...
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Application of Single-Cell Sequencing on Stem Cell Research
The variation and heterogeneity within cells are the fundamental features of stem cells. Each tissue has a resident stem cell niche compartmentalized...
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Transcriptomic profiling across human serotonin neuron differentiation via the FEV reporter system
BackgroundThe detailed transcriptomic profiles during human serotonin neuron (SN) differentiation remain elusive. The establishment of a reporter...
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Scanorama: integrating large and diverse single-cell transcriptomic datasets
Merging diverse single-cell RNA sequencing (scRNA-seq) data from numerous experiments, laboratories and technologies can uncover important biological...
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Emerging tools for uncovering genetic and transcriptomic heterogeneities in bacteria
Bacterial communities display an astonishing degree of heterogeneities among their constituent cells across both the genomic and transcriptomic...
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Tea Plant Genomic, Transcriptomic, and Metabolic Databases
Tea plant, an important nonalcoholic beverage crop, is extensively cultivated worldwide. The exponential growth of biological sequence data has made...
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Quartet RNA reference materials improve the quality of transcriptomic data through ratio-based profiling
Certified RNA reference materials are indispensable for assessing the reliability of RNA sequencing to detect intrinsically small biological...
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PhyloVelo enhances transcriptomic velocity field map** using monotonically expressed genes
Single-cell RNA sequencing (scRNA-seq) is a powerful approach for studying cellular differentiation, but accurately tracking cell fate transitions...
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Transcriptomic Approach for Global Distribution of SNP/Indel and Plant Genoty**
Single Nucleotide Polymorphisms (SNPs) are the most common structural variants found in any genome. They have been used for different genetic...
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Identification of a novel transcription factor under long-term drought resistance in highland barley: a DNA affinity purification sequencing-based transcriptomic analysis
Stress emanating from drought condition is one of the inevitable conditions that occurs in many environments and spread across borders and results in...
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A proteo-transcriptomic map of non-alcoholic fatty liver disease signatures
Non-alcoholic fatty liver disease (NAFLD) is a common, progressive liver disease strongly associated with the metabolic syndrome. It is unclear how...
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Transcriptomic responses in the nervous system and correlated behavioural changes of a cephalopod exposed to ocean acidification
BackgroundThe nervous system is central to coordinating behavioural responses to environmental change, likely including ocean acidification (OA)....
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Stress-free single-cell transcriptomic profiling and functional genomics of murine eosinophils
Eosinophils are a class of granulocytes with pleiotropic functions in homeostasis and various human diseases. Nevertheless, they are absent from...
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Computational approaches identify a transcriptomic fingerprint of drug-induced structural cardiotoxicity
Structural cardiotoxicity (SCT) presents a high-impact risk that is poorly tolerated in drug discovery unless significant benefit is anticipated....
