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Showing 1-20 of 95 results
  1. Serum lipid metabolism characteristics and potential biomarkers in patients with unilateral sudden sensorineural hearing loss

    Background

    Glycerophospholipids (GPLs) are essential for cell membrane structure and function. Sphingomyelin and its metabolites regulate cell growth,...

    **aoyan Chen, Zhong Zheng, ... Yanmei Feng in Lipids in Health and Disease
    Article Open access 29 June 2024
  2. Natural products: protective effects against sensorineural hearing loss

    Hearing loss is one of the major public health problems in the world, which brings huge adverse effects to individuals and society. Sensorineural...

    Wenqi Xu, Mao Huang, ... Rong Chen in Phytochemistry Reviews
    Article 04 April 2024
  3. Advances in the Study of Etiology and Molecular Mechanisms of Sensorineural Hearing Loss

    Sensorineural hearing loss (SNHL), a multifactorial progressive disorder, results from a complex interplay of genetic and environmental factors, with...

    Cairong He, Hongcun Gai, ... Jie Ding in Cell Biochemistry and Biophysics
    Article 07 June 2024
  4. Spectral Characteristics of Cardinal Vowels as Indicators of the Auditory Speech Feedback Control in Patients with Moderate and Moderately Severe Chronic Postlingual Sensorineural Hearing Loss

    Abstract

    Chronic sensorineural hearing loss (SNHL) is characterized by an increase in hearing thresholds at basic speech frequencies, which implies...

    K. S. Shtin, A. M. Lunichkin, ... I. G. Andreeva in Journal of Evolutionary Biochemistry and Physiology
    Article 01 March 2023
  5. Hearing loss and vestibular schwannoma: new insights into Schwann cells implication

    Hearing loss (HL) is the most common and heterogeneous disorder of the sensory system, with a large morbidity in the worldwide population. Among...

    Tasnim Mohamed, Valentina Melfi, ... Valerio Magnaghi in Cell Death & Disease
    Article Open access 23 September 2023
  6. The protective effects of systemic dexamethasone on sensory epithelial damage and hearing loss in targeted Cx26-null mice

    Mutations in the GJB2 gene (encoding Connexin26(Cx26)) are the most common cause of hereditary deafness, accounting for about a quarter of all cases....

    Kai Xu, Sen Chen, ... Yu Sun in Cell Death & Disease
    Article Open access 10 June 2022
  7. Deafness gene screening based on a multilevel cascaded BPNN model

    Sudden sensorineural hearing loss is a common and frequently occurring condition in otolaryngology. Existing studies have shown that sudden...

    **ao Liu, Li Teng, ... **g Sun in BMC Bioinformatics
    Article Open access 20 February 2023
  8. Mesenchymal stem cells for sensorineural hearing loss: a systematic review of preclinical studies

    Sensorineural hearing loss (SNHL) is the most common form of hearing loss that is routinely treated with hearing aids or cochlear implants. Advances...

    Kevin Chorath, Matthew Willis, ... Alvaro Moreira in Molecular Biology Reports
    Article 22 April 2020
  9. The atherogenic index (ATH index) as a potential predictive marker of idiopathic sudden sensorineural hearing loss: a case control study

    Background

    The importance of blood lipids in the pathogenesis of sudden sensorineural hearing loss (SSNHL) is widely discussed in the literature....

    Anastasiya M. Kaneva, Yury K. Yanov, ... Jon Ø. Odland in Lipids in Health and Disease
    Article Open access 15 March 2019
  10. Exome sequencing of families from Ghana reveals known and candidate hearing impairment genes

    We investigated hearing impairment (HI) in 51 families from Ghana with at least two affected members that were negative for GJB2 pathogenic variants....

    Ambroise Wonkam, Samuel Mawuli Adadey, ... Suzanne M. Leal in Communications Biology
    Article Open access 19 April 2022
  11. Childhood-related neural genotype–phenotype in ATP1A3 mutations: comprehensive analysis

    Background

    ATP1A3 is a gene that encodes the ATPase Na + /K + transporting subunit alpha-3 isoenzyme that is widely expressed in GABAergic neurons....

    Osama Y. Muthaffar, Asma Alqarni, ... Muhammad Imran Naseer in Genes & Genomics
    Article 19 January 2024
  12. Fibrinogen to HDL-Cholesterol ratio as a predictor of mortality risk in patients with acute myocardial infarction

    Background

    Acute myocardial infarction (AMI) is characterized by inflammation, oxidative stress, and atherosclerosis, contributing to increased...

    Congzhuo Jia, Wanying Wu, ... Jiyan Chen in Lipids in Health and Disease
    Article Open access 25 March 2024
  13. Target Organs of Metals Released from Metal-on-Polyethylene Knee and Hip Arthroplasty Implants: Implications for Tissue Metal Profiles 

    Metals are used in orthopedic implants. The wear of arthroplasty implant can lead to the release of arthroprosthetic metals, both locally and...

    Marie Bellouard, Geoffroy Lorin de la GrandMaison, ... Jean-Claude Alvarez in Biological Trace Element Research
    Article 28 June 2024
  14. The Impact of Chronic Magnesium Deficiency on Excitable Tissues—Translational Aspects

    Neuromuscular excitability is a vital body function, and Mg 2+ is an essential regulatory cation for the function of excitable membranes. Loss of Mg 2+ ...

    Marija Stanojević, Nadezda Djuricic, ... Jelena Nesovic Ostojic in Biological Trace Element Research
    Article 06 May 2024
  15. Gene Editing Technologies Targeting TFAM and Its Relation to Mitochondrial Diseases

    Mitochondria are organelles present in the cytoplasm of eukaryotic cells; they play a key role in adenosine triphosphate (ATP) synthesis and...
    Vanessa Cristina de Oliveira, Kelly Cristine Santos Roballo, ... Carlos Eduardo Ambrósio in Genome Editing in Biomedical Sciences
    Chapter 2023
  16. Auditory function and dysfunction: estrogen makes a difference

    Estrogen is the major female hormone involved in reproductive functions, but it also exerts a variety of additional roles in non-reproductive organs....

    Amandine Delhez, Philippe Lefebvre, ... Laurence Delacroix in Cellular and Molecular Life Sciences
    Article 14 September 2019
  17. Miscellaneous CNS Viral Infections: Underappreciated Causes of Neurologic Disease

    Lymphocytic choriomeningitis virus (LCMV) is from the family, Arenaviridae, having single- stranded RNA genome. Adult lymphocytic choriomeningitis...
    Chapter 2023
  18. Cochlear Capillary Pericytes

    Capillary pericytes in the cochlea of mammals are—compared to pericytes in other tissues, like the CNS—relatively poorly researched. To begin with,...
    Martin Canis, Mattis Bertlich in Pericyte Biology in Different Organs
    Chapter 2019
  19. From the regulatory mechanism of TFEB to its therapeutic implications

    Transcription factor EB (TFEB), known as a major transcriptional regulator of the autophagy-lysosomal pathway, regulates target gene expression by...

    Huixia Chen, Siqiao Gong, ... **aoyu Li in Cell Death Discovery
    Article Open access 16 February 2024
  20. Advances in monolingual and crosslingual automatic disability annotation in Spanish

    Background

    Unlike diseases, automatic recognition of disabilities has not received the same attention in the area of medical NLP. Progress in this...

    Iakes Goenaga, Edgar Andres, ... Aitziber Atutxa in BMC Bioinformatics
    Article Open access 26 June 2023
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