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1. Identification of potential genetic causal variants for obesity-related traits using statistical fine map**

   Background

   Obesity is highly influenced by heritability and variant effects. While previous genome-wide association studies (GWASs) have successfully...

   Rui Gong, Jonathan Greenbaum, ... Hong-Wen Deng in Molecular Genetics and Genomics

   Article 27 July 2023
   

2. Expression of Reactive Oxygen Species in Junctional and Pocket Epithelium

   The generation of reactive oxygen species (ROS) is part of an antimicrobial response to pathogenic challenge and potentially has a deleterious effect...

   Daisuke Ekuni, James D. Firth, Edward E. Putnins in Studies on Periodontal Disease

   Chapter 2014
   

3. Macrodomain-containing proteins: regulating new intracellular functions of mono(ADP-ribosyl)ation

   ADP-ribosylation of proteins was first described in the early 1960's, and today the function and regulation of poly(ADP-ribosyl)ation (PARylation) is...

   Karla L. H. Feijs, Alexandra H. Forst, ... Bernhard Lüscher in Nature Reviews Molecular Cell Biology

   Article 05 June 2013
   

4. Transcription factor RUNX1

   Transcription factor RUNX1 is one of the key regulatory proteins in vertebrates. RUNX1 controls hematopoiesis and angiogenesis and is indispensable...

   E. N. Markova, N. V. Petrova, ... O. L. Kantidze in Molecular Biology

   Article 01 November 2012

5. Proteomic and transcriptomic analysis of heart failure due to volume overload in a rat aorto-caval fistula model provides support for new potential therapeutic targets - monoamine oxidase A and transglutaminase 2

   Background

   Chronic hemodynamic overloading leads to heart failure (HF) due to incompletely understood mechanisms. To gain deeper insight into the...

   Jiri Petrak, Jana Pospisilova, ... Vojtech Melenovsky in Proteome Science

   Article Open access 11 November 2011
   

6. Keratin 18 attenuates estrogen receptor α-mediated signaling by sequestering LRP16 in cytoplasm

   Background

   Oncogenesis in breast cancer is often associated with excess estrogen receptor α(ERα) activation and overexpression of its coactivators....

   Yuanguang Meng, Zhiqiang Wu, ... Weidong Han in BMC Cell Biology

   Article Open access 26 December 2009
   

7. Estrogen deficiency reversibly induces telomere shortening in mouse granulosa cells and ovarian aging in vivo

   Estrogen is implicated as playing an important role in aging and tumorigenesis of estrogen responsive tissues; however the mechanisms underlying the...

   Sharyn Bayne, He Li, ... Jun-** Liu in Protein & Cell

   Article 15 May 2011

8. Regulation of intestinal epithelial cells transcriptome by enteric glial cells: impact on intestinal epithelial barrier functions

   Background

   Emerging evidences suggest that enteric glial cells (EGC), a major constituent of the enteric nervous system (ENS), are key regulators of...

   Laurianne Van Landeghem, Maxime M Mahé, ... Michel Neunlist in BMC Genomics

   Article Open access 02 November 2009
   

9. Induction of the LRP16 gene by estrogen promotes the invasive growth of Ishikawa human endometrial cancer cells through the downregulation of E-cadherin

   LRP16 was previously identified as an estrogen-induced gene in breast cancer cells. The responsiveness of LRP16 to estrogen and its functional...

   Yuan Guang Meng, Wei Dong Han, ... Yi Ming Mu in Cell Research

   Article 25 September 2007