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Association between triglyceride-glucose index and low-density lipoprotein particle size in korean obese adults
BackgroundSmall dense low-density lipoprotein cholesterol (sdLDL-C) is the lipoprotein marker among the various lipoproteins that is most strongly...
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The LDL-C/ApoB ratio predicts cardiovascular and all-cause mortality in the general population
BackgroundGenerally, low-density lipoprotein (LDL) particle size can be inferred from the LDL cholesterol concentration to total apolipoprotein B...
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The beneficial effects of nutraceuticals and natural products on small dense LDL levels, LDL particle number and LDL particle size: a clinical review
Cardiovascular diseases (CVDs) are globally the major causes of morbidity and mortality. Evidence shows that smaller and denser low-dense lipoprotein...
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An improved method for estimating low LDL-C based on the enhanced Sampson-NIH equation
BackgroundThe accurate measurement of Low-density lipoprotein cholesterol (LDL-C) is critical in the decision to utilize the new lipid-lowering...
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Genetic or therapeutic neutralization of ALK1 reduces LDL transcytosis and atherosclerosis in mice
Low-density lipoprotein (LDL) accumulation in the arterial wall contributes to atherosclerosis initiation and progression
1 . Activin A receptor-like...
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N-3 fatty acid supplementation mediates lipid profile, including small dense LDL, when combined with statins: a randomized double blind placebo controlled trial
BackgroundEpidemiological and clinical evidence suggests that high-dose intake of omega 3 fatty acids (n-3 FA) have a favorable role in altering...
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The effects of fat consumption on low-density lipoprotein particle size in healthy individuals: a narrative review
Cardiovascular disease (CVD) is the number one contributor to death in the United States and worldwide. A risk factor for CVD is high serum...
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Accumulation of LDL/ox-LDL in the necrotic region participates in osteonecrosis of the femoral head: a pathological and in vitro study
BackgroundOsteonecrosis of the femoral head (ONFH) is a common but intractable disease that appears to involve lipid metabolic disorders. Although...
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Preparation of LDL , Oxidation , Methods of Detection, and Applications in Atherosclerosis Research
The concept of lipid peroxidation has been known for a long time. It is now well established that LDL plays a major role in atherosclerosis. Oxidized...
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High-throughput measurement of the content and properties of nano-sized bioparticles with single-particle profiler
We introduce a method, single-particle profiler, that provides single-particle information on the content and biophysical properties of thousands of...
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Associations of maternal lipoprotein particle distribution in mid-pregnancy with birth outcomes: a pilot study
BackgroundAn excessive rise in maternal lipids during pregnancy may have detrimental impacts on maternal and fetal health leading to adverse...
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Pemafibrate decreases triglycerides and small, dense LDL, but increases LDL-C depending on baseline triglycerides and LDL-C in type 2 diabetes patients with hypertriglyceridemia: an observational study
BackgroundPemafibrate, a selective PPARα modulator, has the beneficial effects on serum triglycerides (TGs) and very low density lipoprotein (VLDL),...
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NMR derived changes of lipoprotein particle concentrations related to impaired fasting glucose, impaired glucose tolerance, or manifest type 2 diabetes mellitus
BackgroundType 2 diabetes mellitus (T2D) and corresponding borderline states, impaired fasting glucose (IFG) and/or glucose tolerance (IGT), are...
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Non-invasive skin cholesterol testing: a potential proxy for LDL-C and apoB serum measurements
BackgroundLipid management is the first line of treatment for decreasing the incidence of cardiovascular events in patients with coronary heart...
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Effects of portable pedal machines at work on lipoprotein subfraction profile in sedentary workers – the REMOVE study
BackgroundSedentary behaviour at work is a major cause of atherosclerosis, particularly in tertiary workers. However, no studies have ever assessed...
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Discordance between apolipoprotein B or non-HDL-cholesterol and LDL-cholesterol in middle-aged and elderly Chinese patients predicts arterial stiffness
BackgroundDiscordance of lipid parameters is closely associated with residual cardiovascular risk. This study investigated the discordance between...
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Reductions of copper ion-mediated low-density lipoprotein (LDL) oxidations of trypsin inhibitors, the sweet potato root major proteins, and LDL binding capacities
BackgroundThe root major proteins of sweet potato trypsin inhibitors (SPTIs) or named sporamin, estimated for 60 to 80% water-soluble proteins,...
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Adipose tissue dysfunction serum markers are associated with high density lipoprotein size and glycation in the early stages of type 2 diabetes
BackgroundHigh-density lipoproteins (HDLs) have antiatherogenic properties related to their chemical structure. Adipose tissue (AT) influences HDL...
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Lipoprotein subfraction patterns throughout gestation in The Gambia: changes in subfraction composition and their relationships with infant birth weights
BackgroundLipoprotein subfraction concentrations have been shown to change as gestation progresses in resource-rich settings. The objective of the...
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Isolation of Circulating Extracellular Vesicles by High-Performance Size-Exclusion Chromatography
Circulating extracellular vesicles (EVs) are gaining increased attention as carriers of proteins, nucleic acids, and lipids. Blood contains EVs from...