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Systematic proteomics profiling of lysine crotonylation of the lung at Pseudoglandular and Canalicular phases in human fetus
Lung tissue is an important organ of the fetus, and genomic research on its development has improved our understanding of the biology of this tissue....
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Quadruplex qPCR for detection and discrimination of C. Coli,C. fetus, and C. Jejuni from other Campylobacter species in chicken and sheep meat
Campylobacter is gram-negative bacteria considered the predominant genera isolated from poultry samples and associated with gastroenteritis. Due to...
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Assessing Cholesterol Efflux on Primary Human Trophoblast Cells
Cholesterol transport across the placenta must be tightly regulated to avoid a deficiency or an oversupply of cholesterol which is transferred from...
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Neuronal progenitors of the dentate gyrus express the SARS-CoV-2 cell receptor during migration in the develo** human hippocampus
The COVID-19 pandemic spread around the world is due to the enormous capacity of the SARS-CoV-2 coronavirus to be transmitted between humans, causing...
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Sexual dimorphism of the human fetal pelvis exists at the onset of primary ossification
Human adolescent and adult skeletons exhibit sexual dimorphism in the pelvis. However, the degree of sexual dimorphism of the human pelvis during...
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Three-Dimensional In Vitro Human Placental Organoids from Mononuclear Villous Trophoblasts or Trophoblast Stem Cells to Understand Trophoblast Dysfunction in Fetal Growth Restriction
The placentaPlacenta plays a critical role in the efficient delivery of nutrients and oxygen from mother to fetus to maintain normal fetal growth....
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Ensemble learning for predicting ex vivo human placental barrier permeability
BackgroundThe placental barrier protects the fetus from exposure to some toxicants and is vital for drug development and risk assessment of...
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Human Microbiome and Lifestyle Disorders
The human microbiome builds a multifaceted and dynamic ecosystem with the body that shapes the metabolic as well as immunological behavior of human...
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The important biological roles of Syncytin-1 of human endogenous retrovirus W (HERV-W) and Syncytin-2 of HERV-FRD in the human placenta development
Background: Human endogenous retroviruses (HERVs) entered the germ line by retroviral infection from a distant ancestor over 30 million years ago and...
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Molecular investigation of Coxiella burnetii in aborted fetus of small ruminants in southeast Iran
The domestic animal, known as a main reservoir of Coxiella burnetii , is susceptible to the occurrence of coxiellosis, which can lead to abortions in...
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Proteomic studies of VEGFR2 in human placentas reveal protein associations with preeclampsia, diabetes, gravidity, and labor
VEGFR2 (Vascular endothelial growth factor receptor 2) is a central regulator of placental angiogenesis. The study of the VEGFR2 proteome of...
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Role of Albumin and Alpha-Fetoprotein in Prenatal Ontogenesis of the Human Eye
AbstractThe vitreous body of the eye of human fetuses contains serum albumin (SA) and alpha-fetoprotein (AFP), which is normally characteristic of...
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Human post-implantation blastocyst-like characteristics of Muse cells isolated from human umbilical cord
Muse cells, identified as cells positive for the pluripotent surface marker SSEA-3, are pluripotent-like endogenous stem cells located in the bone...
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Generation of 3D Trophoblast Organoids from Human Naïve Pluripotent Stem Cells
The human placenta is a transient organ that functions to support the needs of the fetus throughout gestation. Trophoblasts are the major epithelial...
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Global metabolomic profiling reveals hepatic biosignatures that reflect the unique metabolic needs of late‐term mother and fetus
ObjectiveGestational disorders including preeclampsia, growth restriction and diabetes are characterized, in part, by altered metabolic interactions...
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Human fetal whole-body postmortem microfocus computed tomographic imaging
Perinatal autopsy is the standard method for investigating fetal death; however, it requires dissection of the fetus. Human fetal microfocus computed...
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Induction of human trophoblast stem cells
Cell reprogramming has allowed unprecedented access to human development, from virtually any genome. However, reprogramming yields pluripotent stem...
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Trajectories of brain and behaviour development in the womb, at birth and through infancy
Birth is often seen as the starting point for studying effects of the environment on human development, with much research focused on the capacities...
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A comprehensive review of human trophoblast fusion models: recent developments and challenges
As an essential component of the maternal-fetal interface, the placental syncytiotrophoblast layer contributes to a successful pregnancy by secreting...
