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Glutathione supplementation improves fat graft survival by inhibiting ferroptosis via the SLC7A11/GPX4 axis
BackgroundAutologous fat grafting is hampered by unpredictable graft survival, which is potentially regulated by ferroptosis. Glutathione (GSH), a...
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Synthesis and characterization of lignin-graft-polyacrylamide copolymers: effect of type and concentration of initiator and co-initiator, monomer concentration, and reaction temperature and time on efficiency of graft copolymerization
This study involves the graft copolymerization of acrylamide onto lignin through a free radical polymerization process initiated using six distinct...
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The Role of NK Cells and Their Exosomes in Graft Versus Host Disease and Graft Versus Leukemia
Natural killer (NK) cells are one of the innate immune cells that play an important role in preventing and controlling tumors and viral diseases, but...
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Untargeted NMR-based metabolomics analysis of kidney allograft perfusates identifies a signature of delayed graft function
IntroductionKidney transplantation (KTx) necessarily conveys an ischemia/reperfusion (I/R) process, which impacts on allograft outcomes. Delayed...
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Graft failure after allogeneic hematopoietic stem cell transplantation in pediatric patients with acute leukemia: autologous reconstitution or second transplant?
BackgroundGraft failure (GF) is a rare but serious complication after allogeneic hematopoietic stem cell transplantation (HSCT). Prevention of graft...
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Prediction of delayed graft function by early salivary microbiota following kidney transplantation
AbstractDelayed graft function (DGF) is a frequently observed complication following kidney transplantation (KT). Our prior research revealed dynamic...
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Implantation of Adipose-Derived Mesenchymal Stromal Cells (ADSCs)-Lining Prosthetic Graft Promotes Vascular Regeneration in Monkeys and Pigs
Background:Current replacement procedures for stenosis or occluded arteries using prosthetic grafts have serious limitations in clinical...
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A conserved graft formation process in Norway spruce and Arabidopsis identifies the PAT gene family as central regulators of wound healing
The widespread use of plant grafting enables eudicots and gymnosperms to join with closely related species and grow as one. Gymnosperms have...
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Islet Macroencapsulation: Strategies to Boost Islet Graft Oxygenation
Islet transplantation is a valid therapy for patients with type 1 diabetes. However, a widespread application is hampered by mandatory requirement of...
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A Comparative Study of an Anti-Thrombotic Small-Diameter Vascular Graft with Commercially Available e-PTFE Graft in a Porcine Carotid Model
Background:We have designed a reinforced drug-loaded vascular graft composed of polycaprolactone (PCL) and polydioxanone (PDO) via a combination of...
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Tetramerization of pyruvate kinase M2 attenuates graft-versus-host disease by inhibition of Th1 and Th17 differentiation
Lethal graft-versus-host disease (GVHD) is the major complication of allogeneic hematopoietic stem-cell transplantation (Allo-HSCT). Pyruvate kinase...
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Spatial and temporal alterations of multiple hormones during the graft union formation process in walnut (Juglans regia)
Plant grafting involves naturally or intentionally merging distinct plant parts to form a single organism. Although it is a common horticultural...
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Glucocorticoid and glycolysis inhibitors cooperatively abrogate acute graft-versus-host disease
Although glucorticosteroids (GCs) are the standard first-line therapy for acute graft-versus-host disease (aGvHD), nearly 50% of aGvHD patients have...
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Early detection of graft incompatibility in sweet cherry by internode association and callus fusion techniques
The scion-rootstock incompatibility is one of the most common problems in fruit trees. The study evaluated predicted compatibility or incompatibility...
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Altered microbial bile acid metabolism exacerbates T cell-driven inflammation during graft-versus-host disease
Microbial transformation of bile acids affects intestinal immune homoeostasis but its impact on inflammatory pathologies remains largely unknown....
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Assessment of a Tissue-Engineered Vascular Graft Based on a Biodegradable Scaffold and Mesenchymal Stem Cells in a Long-Term Experiment In Vivo
AbstractA biodegradable tubular poly(L-lactide) scaffold and a method for seeding and culturing mesenchymal stem cells were developed to create a...
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Graft dislocation following Descemet strip** automated endothelial keratoplasty: a comparative cohort analysis of Optisol GS and organ culture preserved corneas
Previous studies have suggested risk factors for graft dislocation after Descemet strip** automated endothelial keratoplasty (DSAEK). We aimed to...
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The effect of lncRNA MIR155HG-modified MSCs and exosome delivery to synergistically attenuate vein graft intimal hyperplasia
BackgroundThe mesenchymal stem cells (MSCs) were used to repair tissue injury. However, the treatment effect was not satisfactory. We investigated...
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Adenosine-Prefabricated Adipose Tissue Improves Fat Graft Survival by Promoting VEGF-Dependent Angiogenesis
BACKGROUND:Angiogenesis plays an important role in determining the fat graft survival. However, clinical preconditioning techniques that target...
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A non-invasive system to monitor in vivo neural graft activity after spinal cord injury
Expectations for neural stem/progenitor cell (NS/PC) transplantation as a treatment for spinal cord injury (SCI) are increasing. However, whether and...
