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Research and Clinical Approaches to Undiagnosed Rare Genetic Disorders
Rare genetic diseases are complex and heterogeneous. The diagnostic challenges of undiagnosed rare genetic disorders are due to their diversity and... -
Analyzing Autopolyploid Genetic Data Using GenoDive
Analyzing autopolyploid genetic data still presents numerous challenges due to, e.g., missing dosage information of genotypes and the presence of... -
Genetic Resources
Nature has bestowed with abundant wealth of genetic resources (plants, animals, microorganisms, forests). Genetic resources play a crucial role in... -
Conservation of Plant Genetic Resources in Italy
An attempt is made to summarize decades of activities by many national and international actors and institutions that created ideal research... -
Disease Models for Rare Genetic Disorders
Rare diseases pose complex challenges to individuals, families, and the healthcare system. Collaborative research efforts are essential to improving... -
Editing Genetic Material
In the preceding sections we have become acquainted with cases in which genetic diagnostics led to a reduction of hereditary diseases in population... -
On the Trail of Spatial Patterns of Genetic Variation
The accurate determination of the spatial trends on the variability of a species’ gene pool is essential to elucidate the underlying...
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Genetic recording of in vivo cell proliferation by ProTracer
The ability to experimentally measure cell proliferation is the basis for understanding the sources of cells that drive organ development, tissue...
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Enhancement of Plant Secondary Metabolites by Genetic Manipulation
Secondary metabolites comprise the large repository of biomolecules, which are biosynthesized by bacteria, plants, and microorganisms. The... -
Documenting the biodiversity of edible grasshoppers in South Africa with traditional knowledge, classic taxonomy and genetic information
The diversity of edible grasshoppers worldwide remains largely undocumented due to inconsistent reporting of ethno- and scientific species, and...
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Genetic manipulation of giant viruses and their host, Acanthamoeba castellanii
Giant viruses (GVs) provide an unprecedented source of genetic innovation in the viral world and are thus, besides their importance in basic and...
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Genetic Resources and Breeding Approaches for Improvement of Ferula assa-foetida (Heeng)
Ferula assa-foetida L. is a perennial and monoecious herb belonging to Apiaceae/Umbelliferae family. This species is grown wild in Iran, Afghanistan,... -
Investigating Tissue Regeneration Using the DUAL Control Genetic Ablation System
Genetic ablation is a highly efficient method to study regeneration in vivo by stimulating tissue-specific cell death that subsequently induces... -
Genome-wide association study, population structure, and genetic diversity of the tea plant in Guizhou Plateau
BackgroundGuizhou Plateau, as one of the original centers of tea plant, has a profound multi-ethnic cultural heritage and abundant tea germplasm...
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Mutation and Genetic Drift
The emergence of genetic variation in natural and simulated populations depends on the production of new variants. The engine of variant production... -
Assessment of variability and genetic divergence of longan genotypes (Dimocarpus longan Lour.) based on qualitative and quantitative traits
Longan ( Dimocarpus longan Lour.) is an important underutilized fruit crop. There is currently limited information available on the genetic background...
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Morphological to Molecular Markers: Plant Genetic Diversity Studies in Walnut (Juglans regia L.)—A Review
Persian walnut populations have tremendous morphological and allelic diversity in their germplasm due to heavy outcrossing and years of seed...
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Optimal experimental designs for estimating genetic and non-genetic effects underlying infectious disease transmission
BackgroundThe spread of infectious diseases in populations is controlled by the susceptibility (propensity to acquire infection), infectivity...
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Emerging tools for uncovering genetic and transcriptomic heterogeneities in bacteria
Bacterial communities display an astonishing degree of heterogeneities among their constituent cells across both the genomic and transcriptomic...