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METTL3-dependent m6A modification of PSEN1 mRNA regulates craniofacial development through the Wnt/β-catenin signaling pathway
Craniofacial malformations, often associated with syndromes, are prevalent birth defects. Emerging evidence underscores the importance of m 6 A...
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Craniofacial Development Methods and Protocols
This volume explores scientific methodologies currently employed to integrate observational developmental biology, tissue explant and cell-based...
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Morphometric analysis of the size-adjusted linear dimensions of the skull landmarks revealed craniofacial dysmorphology in Mid1-cKO mice
BackgroundThe early craniofacial development is a highly coordinated process involving neural crest cell migration, proliferation, epithelial...
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Substrate type induces plastic responses in the craniofacial morphology of a winnowing cichlid
Understanding how local populations respond to specific changes in the environment can help us better predict how populations respond to such change....
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Scaffolds for Use in Craniofacial Bone Regeneration
Tissue-engineered scaffolds have been identified as appropriate templates for bone regeneration, especially complex geometries seen in craniofacial...
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One Genus or Two? Evaluating Whether Gracile and Robust Capuchin Monkeys are Validly Classified as Separate Genera Based on Craniofacial Shape
Assessments of whether closely related species should be classified into more than one genus have been a longstanding source of controversy in...
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A novel technique for aging male African elephants (Loxodonta africana) using craniofacial photogrammetry and geometric morphometrics
Shoulder height, hind foot length, and photogrammetric craniofacial measurements were collected from male African elephants ( Loxodonta africana ) in...
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Adipose-derived stem cell spheroid-laden microbial transglutaminase cross-linked gelatin hydrogel for treating diabetic periodontal wounds and craniofacial defects
BackgroundDiabetes mellitus deteriorates the destruction and impairs the healing of periodontal wounds and craniofacial defects. This study is to...
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The genomic landscape of mammal domestication might be orchestrated by selected transcription factors regulating brain and craniofacial development
Domestication transforms once wild animals into tamed animals that can be then exploited by humans. The process entails modifications in the body,...
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Expression of Cre recombinase in chondrocytes causes abnormal craniofacial and skeletal development
The cranial base synchondroses are growth centers that drive cranial and upper facial growth. The intersphenoid synchondrosis (ISS) and the...
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Craniofacial Phenomics: Three-Dimensional Assessment of the Size and Shape of Cranial and Dentofacial Structures
Craniofacial phenomics has opened up numerous opportunities to correlate genetic and epigenetic factors to craniofacial phenotypes in order to...
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Histological Techniques for Sectioning Bones of the Vertebrate Craniofacial Skeleton
Histochemical analysis is an indispensable technique in the field of biology used routinely to characterize pathologies of interest throughout the...
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Genetic map** of craniofacial traits in the Mexican tetra reveals loci associated with bite differences between cave and surface fish
BackgroundThe Mexican tetra, Astyanax mexicanus, includes interfertile surface-dwelling and cave-dwelling morphs, enabling powerful studies aimed at...
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Elucidation of Gene Expression Patterns in the Craniofacial Tissues of Mouse Embryos by Wholemount In Situ Hybridization
Analysis of animal models allows a deeper understanding of craniofacial development in health and diseases of humans. Wholemount in situ...
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Visualization of the Cartilage and Bone Elements in the Craniofacial Structures by Alcian Blue and Alizarin Red Staining
Craniofacial morphogenesis is underpinned by orchestrated growth and form-sha** activity of skeletal and soft tissues in the head and face....
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Exosomes derived from stem cells from apical papilla promote craniofacial soft tissue regeneration by enhancing Cdc42-mediated vascularization
BackgroundReconstruction of complex critical-size defects (CSD) in the craniofacial region is a major challenge, and soft tissue regeneration is...
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Differences among families in craniofacial shape at early life-stages of Arctic charr (Salvelinus alpinus)
BackgroundOrganismal fitness can be determined at early life-stages, but phenotypic variation at early life-stages is rarely considered in studies on...
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Wholemount In-Situ Hybridization (WISH) in Zebrafish Embryos to Analyze Craniofacial Development
Wholemount in-situ hybridization in zebrafish is a powerful technique for visualizing spatiotemporal gene expression during development. Here we...
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Using Caenorhabditis elegans as a Model for Mechanistic Insights of Craniofacial Development
Caenorhabditis elegans has served as a powerful model for understanding the molecular and cell biology of clinically important human proteins due to...
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Human levator veli palatini muscle: a novel source of mesenchymal stromal cells for use in the rehabilitation of patients with congenital craniofacial malformations
BackgroundBone reconstruction in congenital craniofacial differences, which affect about 2–3% of newborns, has long been the focus of intensive...
