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The ovine conceptus utilizes extracellular serine, glucose, and fructose to generate formate via the one carbon metabolism pathway
Highly proliferative cells rely on one carbon (1C) metabolism for production of formate required for synthesis of purines and thymidine for nucleic...
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Uterine histotroph and conceptus development: III. Adrenomedullin stimulates proliferation, migration and adhesion of porcine trophectoderm cells via AKT-TSC2-MTOR cell signaling pathway
Adrenomedullin (ADM) as a highly conserved peptide hormone has been reported to increase significantly in the uterine lumen during the...
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Supplementation with long-acting injectable progesterone 3 days after TAI impaired luteal function in buffaloes
Three experiments were conducted to evaluate the effects of long-acting injectable progesterone (iP4) in buffalo cows. In Experiment 1,...
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Integrins and their potential roles in mammalian pregnancy
Integrins are a highly complex family of receptors that, when expressed on the surface of cells, can mediate reciprocal cell-to-cell and...
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RNA-Sequencing based analysis of bovine endometrium during the maternal recognition of pregnancy
BackgroundMaternal recognition is the crucial step for establishing pregnancy in cattle. This study aims to identify endometrial genes and biological...
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Progesterone regulates tissue non-specific alkaline phosphatase (TNSALP) expression and activity in ovine utero-placental tissues
BackgroundTissue non-specific alkaline phosphatase (TNSALP; encoded by the ALPL gene) has a critical role in the postnatal regulation of phosphate...
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Differential transcriptome dynamics during the onset of conceptus elongation and between female and male porcine embryos
BackgroundPorcine embryos undergo rapid differentiation and expansion between Days 8 and 12 before attaching to the maternal uterine epithelial...
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Dietary supplementation with 0.4% L-arginine between days 14 and 30 of gestation enhances NO and polyamine syntheses and water transport in porcine placentae
BackgroundMost embryonic loss in pigs occurs before d 30 of gestation. Dietary supplementation with L -arginine (Arg) during early gestation can...
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Exposure to maternal obesity alters gene expression in the preimplantation ovine conceptus
BackgroundEmbryonic and fetal exposure to maternal obesity causes several maladaptive morphological and epigenetic changes in exposed offspring. The...
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Pre-implantation exogenous progesterone and pregnancy in sheep: I. polyamines, nutrient transport, and progestamedins
BackgroundAdministration of exogenous progesterone (P4) to ewes during the pre-implantation period advances conceptus development and implantation....
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Implantation and Placentation in Ruminants
In comparison to many other mammalian species, ruminant ungulates have a unique form of placentation. Ruminants initially display an epitheliochorial...
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Exacerbated conceptus signaling does not favor establishment of pregnancy in beef cattle
BackgroundInsufficient production of anti-luteolytic signals by the pre-attachment embryo is considered a major cause of pregnancy failure in cattle....
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The role of extracellular vesicles in animal reproduction and diseases
Extracellular vesicles (EVs) are nanosized membrane-enclosed compartments that serve as messengers in cell-to-cell communication, both in normal...
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The Early Stages of Implantation and Placentation in the Pig
Pregnancy in pigs includes the events of conceptus (embryo/fetus and placental membranes) elongation, implantation, and placentation. Placentation in...
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Placentation in Equids
This chapter focuses on the early stages of placental development in horses and their relatives in the genus Equus and highlights unique features of...
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Endometrial response to conceptus-derived estrogen and interleukin-1β at the time of implantation in pigs
AbstractThe establishment of pregnancy is a complex process that requires a well-coordinated interaction between the implanting conceptus and the...
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Poly-implantation and Embryonic Death
Embryo implantation in the vizcacha begins at 18 days post-coitum (dpc). It occurs in the caudocranial direction, that is, from the caudal to the...
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Early Syncytialization of the Ovine Placenta Revisited
Placentation is the development of a temporary arrangement between the maternal uterus and blastocyst-derived placental tissues designed to transport...
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Associations between maternal vitamin D status and porcine litter characteristics throughout gestation
Emerging evidence suggests an important role of vitamin D in the establishment and maintenance of pregnancy, and the regulation of foetal growth...
