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Reduction of UreB and CagA expression level by siRNA construct in Helicobacter pylori strain SS1
BackgroundTwo important virulence factors, urease and cagA, play an important role in Helicobacter pylori ( H. pylori ) gastric cancer. Aim of this...
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Functional antagonism between CagA and DLC1 in gastric cancer
Helicobacter (H.) pylori -induced gastritis is a risk factor for gastric cancer (GC). Deleted-in-liver-cancer-1 (DLC1/ARHGAP7) inhibits RHOA, a...
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Helicobacter pylori cagA, vacA, and iceA genotypes and clinical outcomes: a cross-sectional study in central Vietnam
Helicobacter pylori is the most common cause of gastroduodenal diseases. The concept that cagA -positive H. pylori is a risk factor for gastric cancer...
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Relationship between antibiotic resistance and the cagA and vacA genotypes among Helicobacter pylori strain isolates from patients in **’an
The issue of drug resistance of Helicobacter pylori is becoming increasingly serious. To analyze the correlation between the cagA and vacA genotypes...
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Multiplex Accelerated PCR System for One-Step Helicobacter pylori cagA + Genotypes Detection: A Guide for Clinical Testing
Helicobacter pylori cagA  + genotype is a leading risk factor for gastric cancer development making accurate identification and timely eradication of H....
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Characterization of East-Asian Helicobacter pylori encoding Western EPIYA-ABC CagA
The polymorphic bacterial oncoprotein, CagA shows geography-dependent variation in the C-terminal Glu-Pro-Ile-Tyr-Ala (EPIYA) motifs; East-Asian H....
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Antibacterial Activities of Peptide HF-18 Against Helicobacter pylori and its Virulence Protein CagA
Helicobacter pylori ( H. pylori ) infection is prevalent all over the world, which may even cause gastric cancer. Unfortunately, current antibiotic...
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Export von Gefahrgut: Helicobacter pylori und sein CagA-Protein
Pathogenic bacteria often utilize type IV secretion systems to interact with host cells and to modify their microenvironment in a favourable way. The...
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New strategies for Helicobacter pylori isolation and sequencing analysis for virulence genes contributing to its pathogenicity
BackgroundHelicobacter pylori is a fastidious pathogen that is required a complicated medium for growth. Invading epithelial cells of the stomach. H....
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The cagA EPIYA Motifs and vacA Genotypes in Upper Gastrointestinal Diseases
AbstractBackground: Helicobacter pylori ( H. pylori ) is the causative agent for upper gastrointestinal diseases. The presence of the cagA , at least...
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Crystal Structure Analysis of SH2 Domains in Complex with Phosphotyrosine Peptides
While the number of tertiary structures solved by cryoelectron microscopy has rapidly increased, X-ray crystallography is still a popular method to...
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Helicobacter pylori and Epstein-Barr virus infection in cell polarity alterations
The asymmetrical distribution of the cellular organelles inside the cell is maintained by a group of cell polarity proteins. The maintenance of...
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Relationship between mucosal TNF-α expression and Th1, Th17, Th22 and Treg responses in Helicobacter pylori infection
Helicobacter pylori ( H. pylori )-induced gastric inflammation in the gastric mucosa and significantly increases the risk of develo** gastritis and...
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Frequency of significant virulence genes in gastric biopsies of Helicobacter pylori-positive patients with gastritis
Helicobacter pylori is one of the most common bacteria affecting human societies worldwide, and is mainly associated with gastrointestinal...
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The Anti-Helicobacter pylori effects of Limosilactobacillus reuteri strain 2892 isolated from Camel milk in C57BL/6 mice
Helicobacter pylori infection ( H. pylori ) is associated with chronic gastritis, peptic ulcers, and gastric cancer. The present study provides...
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A comprehensive study of Helicobacter pylori infection: molecular analysis, antibacterial susceptibility, and histopathological examination
Helicobacter pylori is a pathogen associated with gastroduodenal diseases. This study aimed; (i) to investigate H. pylori presence by invasive tests...
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Analysis of Functional Status of Genetically Diverse OipA Gene in Indian Patients with Distinct Gastrointestinal Disease
Helicobacter pylori ( H. pylori, ) a genetically diversified bacteria which colonizes human gastric epithelium, is now established causative agent for...
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SIRT1-targeted miR-543 autophagy inhibition and epithelial–mesenchymal transition promotion in Helicobacter pylori CagA-associated gastric cancer
Gastric cancer is an important cause of death worldwide with Helicobacter pylori ( H. pylori ) considered a leading and known risk factor for its...
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CircMAN1A2 is upregulated by Helicobacter pylori and promotes development of gastric cancer
Helicobacter pylori ( H. pylori ) is one of the main causes of gastric cancer. It has been reported that circRNAs play a vital role in the development...
