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Modifying Bacterial Artificial Chromosomes for Extended Genome Modification
Bacterial artificial chromosomes have been used extensively for the exploration of mammalian genomes. Although novel approaches made their initial... -
Transcription-induced domains form the elementary constraining building blocks of bacterial chromosomes
Transcription generates local topological and mechanical constraints on the DNA fiber, leading to the generation of supercoiled chromosome domains in...
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Dynamics of Bacterial Chromosomes by Locus Tracking in Fluorescence Microscopy
In the last two decades, it has been shown that bacterial chromosomes have remarkable spatial organization at various scales, and they display... -
Plant Cytogenetics: From Chromosomes to Cytogenomics
Chromosomes have been studied since the late nineteenth century in the disciplines of cytology and cytogenetics. Analyzing their numbers, features,... -
Capability of a large bacterial artificial chromosome clone harboring multiple biosynthetic gene clusters for the production of diverse compounds
The biosynthetic gene clusters (BGCs) for the macrocyclic lactone-based polyketide compounds are extremely large-sized because the polyketide...
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Flow Cytometric Analysis and Sorting of Plant Chromosomes
Flow cytometry offers a unique way of analyzing and manipulating plant chromosomes. During a rapid movement in a liquid stream, large populations can... -
Machine learning-aided scoring of synthesis difficulties for designer chromosomes
Designer chromosomes are artificially synthesized chromosomes. Nowadays, these chromosomes have numerous applications ranging from medical research...
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Flow cytometric analysis and sorting of plant chromosomes
Flow cytogenetics is a high-throughput technique that classifies large populations of mitotic chromosomes according to their fluorescence and light...
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Fungal and Bacterial Diseases of Wheat
Wheat (Triticum aestivum L.) is the main staple crop and primary source of starch and energy in human diet. It is grown in over 120 countries in the... -
Molecular characterization of eliminated chromosomes in Hessian fly (Mayetiola destructor (Say))
Like other cecidomyiid Diptera, Hessian fly has stable S chromosomes and dispensable E chromosomes that are retained only in the germ line. Amplified...
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Fluorescence In Situ Hybridization of DNA Probes on Mitotic Chromosomes of the Mexican Axolotl
Fluorescence in situ hybridization (FISH) is used extensively for visual localization of specific DNA fragments (and RNA fragments) in broad... -
MDM2 amplification in rod-shaped chromosomes provides clues to early stages of circularized gene amplification in liposarcoma
Well-differentiated liposarcoma (WDLS) displays amplification of genes on chromosome 12 (Chr12) in supernumerary ring or giant marker chromosomes....
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Telomere-to-telomere assembly of diploid chromosomes with Verkko
The Telomere-to-Telomere consortium recently assembled the first truly complete sequence of a human genome. To resolve the most complex repeats, this...
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Identification of new genetic sources of resistance to bacterial blight race 18 in diploid Asiatic cotton and resistance transfer to tetraploid Upland cotton (Gossypium hirsutum)
Bacterial blight (BB) caused by Xanthomonas citri pv. malvacearum (Xcm), poses a significant threat to Upland cotton ( Gossypium hirsutum L.)...
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Exogenous artificial DNA forms chromatin structure with active transcription in yeast
Yeast artificial chromosomes (YACs) are important tools for sequencing, gene cloning, and transferring large quantities of genetic information....
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ProcaryaSV: structural variation detection pipeline for bacterial genomes using short-read sequencing
BackgroundStructural variations play an important role in bacterial genomes. They can mediate genome adaptation quickly in response to the external...
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Meiotic pairing and double-strand break formation along the heteromorphic threespine stickleback sex chromosomes
Double-strand break repair during meiosis is normally achieved using the homologous chromosome as a repair template. Heteromorphic sex chromosomes...
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Chromosome Painting Using Chromosome-Specific BAC Clones
Chromosome painting (CP) refers to visualization of large chromosome regions, chromosome arms or entire chromosomes via fluorescence in situ... -
Bacterial Endosymbionts of Mucoromycota Fungi: Diversity and Function of their Interactions
Endosymbiotic bacteria are commonly inhabitants of environmental isolates of Mucoromycota fungi. Described bacterial endosymbionts of Mucoromycota... -
Artificial genetic polymers against human pathologies
Originally discovered by Nielsen in 1991, peptide nucleic acids and other artificial genetic polymers have gained a lot of interest from the...