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Molecular Stapling of Human Pediatric RSV Phosphoprotein’s C-terminal Tail-Derived Peptides to Target the Coupled Folding-Upon-Binding Event Between Phosphoprotein and Nucleocapsid
Human respiratory syncytial virus (RSV) has been involved in human pediatric lower respiratory tract infections. The intermolecular interaction...
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A New Species of the Genus Tryphon Fallén, 1813 (Hymenoptera, Ichneumonidae: Tryphoninae) from Israel
AbstractA new species Tryphon levanticus sp. n. is described from Israel and compared with the closely related T. atriceps Stephens, 1835. Both...
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Phenotypic differences among and within extant populations of Chrysanthemum arcticum L. and C. a. subsp. arcticum
BackgroundChrysanthemum arcticum , arctic daisy and its two subspecies ( Chrysanthemum arcticum subsp. arcticum , Chrysanthemum arcticum subsp. polaré )...
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Analyzing Protein–Protein Interactions Using the Split-Ubiquitin System
The split-ubiquitin technology was developed over 20 years ago as an alternative to Gal4-based, yeast-two-hybrid methods to identify interacting...
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Automated design of dynamic programming schemes for RNA folding with pseudoknots
Although RNA secondary structure prediction is a textbook application of dynamic programming (DP) and routine task in RNA structure analysis, it...
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Spatial and temporal dynamics of ATP synthase from mitochondria toward the cell surface
Ectopic ATP synthase complex (eATP synthase), located on cancer cell surface, has been reported to possess catalytic activity that facilitates the...
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Evaluation of biotransformation capacity of transplastomic plants and hairy roots of Nicotiana tabacum expressing human cytochrome P450 2D6
Cytochrome P450 monooxygenases (CYPs) are important tools for regio- and stereoselective oxidation of target molecules or engineering of metabolic...
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Review: structure and modifications of arabinogalactan proteins (AGPs)
The aim of this report is to provide general information on the molecular structure and synthesis of arabinogalactan proteins (AGPs) in association...
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Membrane recruitment of the polarity protein Scribble by the cell adhesion receptor TMIGD1
Scribble (Scrib) is a multidomain polarity protein and member of the leucine-rich repeat and PDZ domain (LAP) protein family. A loss of Scrib...
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Genetic correlations between harvest weight and secondary traits in a silver carp (Hypophthalmichthys molitrix) genetic improvement program
In 2017, the base population of a family-based silver carp ( Hypophthalmichthys molitrix ) genetic improvement program was spawned in Bangladesh. This...
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Molecular characterization and functional analysis of peroxiredoxin 1 (Prx1) from roughskin sculpin (Trachidermus fasciatus)
Peroxiredoxin1( Prx1 ), also known as natural killer enhancing factor A ( NKEF-A ), is a crucial antioxidant involving in various cellular activities and...
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GSKIP modulates cell aggregation through EMT/MET signaling rather than differentiation in SH-SY5Y human neuroblastoma cells
GSK3β interacting protein (GSKIP) is a small A-kinase anchor protein previously reported to mediate the N-cadherin/β-catenin pool for differentiation...
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Structure of a membrane tethering complex incorporating multiple SNAREs
Most membrane fusion reactions in eukaryotic cells are mediated by multisubunit tethering complexes (MTCs) and SNARE proteins. MTCs are much larger...
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Evaluation of the yeast surface display system for screening of functional nanobodies
Yeast surface display is a powerful technology used to isolate and engineer proteins to improve their activity, specificity, and stability. In this...
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PCRCR complex is essential for invasion of human erythrocytes by Plasmodium falciparum
The most severe form of malaria is caused by Plasmodium falciparum . These parasites invade human erythrocytes, and an essential step in this process...
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UNAGI: an automated pipeline for nanopore full-length cDNA sequencing uncovers novel transcripts and isoforms in yeast
Sequencing the entire RNA molecule leads to a better understanding of the transcriptome architecture. SMARTer (Switching Mechanism at 5′-End of RNA...
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Competitive blocking of LRP4–sclerostin binding interface strongly promotes bone anabolic functions
Induction of bone formation by Wnt ligands is inhibited when sclerostin (Scl), an osteocyte-produced antagonist, binds to its receptors, the...
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Identification of LsLAZY1 gene in Leymus secalinus and validation of its function in Arabidopsis thaliana
Root systems anchor plants to the substrate in addition to transporting water and nutrients, playing a fundamental role in plant survival. The LAZY1 ...
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Cryo-EM structure of the inner ring from the Xenopus laevis nuclear pore complex
Nuclear pore complex (NPC) mediates nucleocytoplasmic shuttling. Here we present single-particle cryo-electron microscopy structure of the inner ring...
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Engineering Strategies for Efficient and Sustainable Production of Medium-Chain Length Polyhydroxyalkanoates in Pseudomonads
Most bacteria belonging to the genus Pseudomonas can accumulate medium-chain poly-3-hydroxy-alkanoates (mcl-PHA) as storage materials. For this...