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Assessment of phytometabolite distribution, in vitro antioxidant and anti-inflammatory potential of novel plant, Euphorbia deccanensis—endemic to South India
Chronic diseases, such as different cancers, are primarily caused by inflammation and oxidative stress. Due to their prominent roles, it is believed...
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Preconditioning with Moderate Hypoxia Increases Tolerance to Subsequent Severe Hypoxia in Rats with LPS-Induced Endotoxemia
AbstractHyperproduction of mediators of LPS-induced inflammatory process (endotoxicosis, sepsis) initiates the development of acute...
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The benefits of flushing with Lemuru fish oil as a source of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) on the performance of reproductive parameters in Garut ewes
This study aimed to evaluate and analyze the effects of a flushing diet containing Docosahexaenoic acid (DHA) and Eicosapentaenoic acid (EPA) from...
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Tissue Reconstructive and Regenerative Medicine Approach as an Anti-Aging Intervention: Relevance to Age-Induced Osteoarthritis
Aging is a dynamic, irreversible, and inevitable physiological process associated with gradual deterioration in the overall performance of all the...
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PGD2 displays distinct effects in diffuse large B-cell lymphoma depending on different concentrations
Prostaglandin D2 (PGD2), an arachidonic acid metabolite, has been implicated in allergic responses, parasitic infection and tumor development. The...
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Blood Oxylipin Profiles as Markers of Oncological Diseases
AbstractOxylipins are signal lipid molecules formed from polyunsaturated fatty acids (PUFAs) in several multienzymatic metabolic pathways, such as...
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Transcriptomic comparison of ovarian granulosa cells between adult sheep and prepubertal lambs
BackgroundThe oocyte development ability of prepubertal animals is significantly lower than that of adult animals. Granulosa cells (GCs) have an...
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Comparative Analysis of the Effects of Insulin and Metformin on the Ulcerogenic Action of Indomethacin in Rats with Streptozotocin-Induced Diabetes
AbstractOne consequence of diabetes is gastropathy, manifested by an increase in gastric ulcer formation. Insulin is the primary medication used to...
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Human umbilical cord mesenchymal stem cell-derived treatment of severe pulmonary arterial hypertension
Here we report application of human umbilical cord mesenchymal stem cell (HUCMSC)-derived therapy for pulmonary arterial hypertension (PAH). A...
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Anti-inflammatory Potential of Lead Compounds and Their Derivatives from Medicinal Plants
Inflammation is a double-edged sword that acts against pathogens invasion; whereas undesirable immune responses caused inflammation/tissue damage...
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Similar adaptative mechanism but divergent demographic history of four sympatric desert rodents in Eurasian inland
Phenotypes associated with metabolism and water retention are thought to be key to the adaptation of desert species. However, knowledge on the...
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Canine Endotheliochorial Placenta: Morpho-Functional Aspects
In the domestic dog, placentation arises from central implantation, passing through a transitional, yet important stage of choriovitelline placenta...
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The relationship between OXT gene polymorphisms and reproductive hormones in pregnant and lactating Awassi Ewes
BackgroundNumerous genetic loci interact intricately to control reproduction in mammals. The oxytocin gene ( OXT ) is a promising candidate for...
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Metaboty** the Welsh population of badgers based on thoracic fluid
IntroductionThe European badger ( Meles meles ) is a known wildlife reservoir for bovine tuberculosis (bTB) and a better understanding of the...
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Analysis and Annotation of Phospholipids by Mass Spectrometry-Based Metabolomics
Phospholipids are essential components of membrane lipid bilayers and serve as precursors of multiple signaling molecules, so alterations in their...
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The Vast Utility of Drosophila Oogenesis
In this chapter, we highlight examples of the diverse array of developmental, cellular, and biochemical insights that can be gained by using...
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Low-polarity untargeted metabolomic profiling as a tool to gain insight into seminal fluid
IntroductionA decrease in sperm cell count has been observed along the last several decades, especially in the most developed regions of the world....
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Chemical Composition of Human and Mammalian Milk (A Review)
AbstractThis review describes the chemical composition and properties of milk, as well as its importance for the development of the child and the...
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The potential role of renin angiotensin system in acute leukemia: a narrative review
Acute leukemias (ALs) are the most common cancers in pediatric population. There are two types of ALs: acute lymphoblastic leukemia (ALL) and acute...
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