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In vitro study on the immunomodulatory effects of differently functionalized silver nanoparticles on human peripheral blood mononuclear cells
The interaction of silver nanoparticles (AgNPs) with the immune system has not yet been sufficiently elucidated even though they belong to the most...
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Extracellular production of Ulp1403-621 in leaky E. coli and its application in antimicrobial peptide production
AbstractSmall ubiquitin-like modifier (SUMO) tag is widely used to promote soluble expression of exogenous proteins, which can then be cleaved by...
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The effects of the COVID-19 pandemic on community respiratory virus activity
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused substantial global morbidity and deaths, leading governments to...
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Polyphenol Phytoalexins as the Determinants of Plant Disease Resistance
Polyphenols is a large group of phytochemicals known for diverse roles in plants metabolism, particularly under biotic and abiotic stress...
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Plant Viral Vectors: Important Tools for Biologics Production
Plants have enormous potential for producing a wide range of biologics and therapeutics. Compared to bacterial and mammalian systems, production in...
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Brazilian essential oils as source for the discovery of new anti-COVID-19 drug: a review guided by in silico study
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in China and its spread worldwide has become one of the biggest health...
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Enterovirus-Associated Meningoencephalitis and Enteroviruses in Patients with Acute Encephalitis
Enteroviruses are from the family of Picornaviridae, consisting of hundreds of serotypes, all having single positive-stranded RNA genome. The...
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Cryo-EM structure of the Hippo signaling integrator human STRIPAK
The striatin-interacting phosphatase and kinase (STRIPAK) complex is a large, multisubunit protein phosphatase 2A (PP2A) assembly that integrates...
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NLRP1- A CINDERELLA STORY: a perspective of recent advances in NLRP1 and the questions they raise
NLRP1, while the first inflammasome described, has only recently begun to gain significant attention in disease pathology, inflammation research, and...
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Bocaparvovirus in infants hospitalized in a neonatal intensive care unit in Midwest Brazil during the COVID-19 pandemic (2021–2022)
Human bocaparvoviruses (HBoVs) belong to the Parvoviridae family, being currently classified into four species (HBoV1–4). These viruses have been...
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Invited review: human air-liquid-interface organotypic airway tissue models derived from primary tracheobronchial epithelial cells—overview and perspectives
The lung is an organ that is directly exposed to the external environment. Given the large surface area and extensive ventilation of the lung, it is...
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COVID-19, Influenza, and Other Acute Respiratory Viral Infections: Etiology, Immunopathogenesis, Diagnosis, and Treatment. Part 2. Other Acute Respiratory Viral Infections
The first part of this paper presented the current knowledge on two very significant respiratory diseases with high pandemic potential, COVID-19 and...
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Genealyzer: web application for the analysis and comparison of gene expression data
BackgroundGene expression profiling is a widely adopted method in areas like drug development or functional gene analysis. Microarray data of gene...
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Comparative analysis of single cell lung atlas of bat, cat, tiger, and pangolin
Horseshoe bats ( Rhinolophus sinicus ) might help maintain coronaviruses severely affecting human health, such as severe acute respiratory syndrome...
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Current Trends on Phytochemicals Toward Herbal Medicine Development
Traditional plants are the most promising source of phytochemicals for creating herbal medicines. Numerous biosynthetic metabolic networks are...
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Interaction Between SARS-CoV-2 and Pathogenic Bacteria
The novel human coronavirus, Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which results in the coronavirus disease 2019 (COVID-19),...
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Current Trends on Phytochemicals Toward Herbal Medicine Development
Traditional plants are the most promising source of phytochemicals for creating herbal medicines. Numerous biosynthetic metabolic networks are...
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Rapid Diagnosis of Pneumocystis jirovecii Pneumonia and Respiratory Tract Colonization by Next-Generation Sequencing
ObjectivesTo describe the epidemiology of Pneumocystis jirovecii pneumonia and colonization diagnosed by next-generation sequencing (NGS) and...
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Development of a robust TaqMan probe-based one-step multiplex RT-qPCR for simultaneous detection of SARS-CoV-2 and Influenza A/B viruses
BackgroundDuring the coronavirus disease 2019 (COVID-19) pandemic, the simultaneous detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2...
