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Post-implantation Embryo Development in the South American Plains Vizcacha, Lagostomus maximus (Rodentia, Caviomorpha)
The early embryo development after implantation varies among mammals. In muroid rodents, an egg cylinder is formed by folding during gastrulation;...
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Transcriptome of D14 in vivo x in vitro bovine embryos: is there any difference?
It is well-established that in vitro culture affects quality, gene expression, and epigenetic processes in bovine embryos and that trophectoderm...
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Effects of early pregnancy on the complement system in the ovine thymus
The complement system is crucial for the innate immune system, and complement activation is related to abnormal pregnancy in mice and humans. It is...
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Using the Air–Liquid Interface Approach to Foster Apical–Basal Polarization of Mammalian Female Reproductive Tract Epithelia In Vitro
Oviduct and uterus are key female reproductive organs lined by ciliated simple columnar epithelia, which are the first line of maternal contact with...
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Epigenetics and Nutrition: Molecular Mechanisms and Tissue Adaptation in Developmental Programming
Biological mechanisms regulating normal growth, development, and nutrient utilization are programmed in utero for postnatal growth and adult...
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Guidelines on Developmental Toxicity Tests: Brief Insights
Developmental toxicology is a constantly evolving research field which needs to attend to a complex underlying regulatory network. In order to ensure...
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Sex and fetal genome influence gene expression in pig endometrium at the end of gestation
BackgroundA fine balance of feto-maternal resource allocation is required to support pregnancy, which depends on interactions between maternal and...
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Pre-implantation exogenous progesterone and pregnancy in sheep. II. Effects on fetal-placental development and nutrient transporters in late pregnancy
BackgroundAdministration of progesterone (P4) to ewes during the first 9 to 12 days of pregnancy accelerates blastocyst development by day 12 of...
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Effect of heat exposure on prostaglandin production and expression of COX-2, PGES, PGFS, ITGAV and LGALS15 mRNAs in endometrial epithelial cells of buffalo (Bubalus bubalis)
BackgroundEarly embryonic mortality is one of the major intriguing factors of reproductive failure that causes considerable challenge to the...
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Progesterone differentially affects the transcriptomic profiles of cow endometrial cell types
BackgroundThe endometrium is a heterogeneous tissue composed of luminal epithelial (LE), glandular epithelial (GE), and stromal cells (ST),...
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Regulation of human trophoblast gene expression by endogenous retroviruses
The placenta is a fast-evolving organ with large morphological and histological differences across eutherians, but the genetic changes driving...
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Placentation in the African Elephant (Loxodonta africana)
The female elephant shows a 3-week “follicular phase” to commence her 16-week estrous cycle at the end of which a second surge in pituitary...
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Dynamic intrauterine crosstalk promotes porcine embryo implantation during early pregnancy
Dynamic crosstalk between the embryo and mother is crucial during implantation. Here, we comprehensively profile the single-cell transcriptome of pig...
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Exploring characteristics of placental transcriptome and cord serum metabolome associated with low birth weight in Kele pigs
The neonate with low birth weight (LBW) resulted from intrauterine growth retardation (IUGR) exists a substantial risk of postpartum death. Placental...
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Distinctive aspects of the placental epigenome and theories as to how they arise
The placenta has a methylome dramatically unlike that of any somatic cell type. Among other distinctions, it features low global DNA methylation,...
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Menstrual flow as a non-invasive source of endometrial organoids
Assessment of the endometrium often necessitates a biopsy, which currently involves an invasive, transcervical procedure. Here, we present an...
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Genetic Testing in Recurrent Pregnancy Loss
Human pregnancy is a surprisingly inefficient process; approximately 5–10% of clinically recognized pregnancies end in miscarriages. Approximately...
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Dietary L-arginine supplementation during days 14–25 of gestation enhances aquaporin expression in the placentae and endometria of gestating gilts
This study tested the hypothesis that dietary L-arginine (Arg) supplementation to pregnant gilts enhanced the expression of water channel proteins...
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Analysis of the transcriptome of bovine endometrial cells isolated by laser micro-dissection (1): specific signatures of stromal, glandular and luminal epithelial cells
BackgroundA number of studies have examined mRNA expression profiles of bovine endometrium at estrus and around the peri-implantation period of...
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The significance of N-carbamoylglutamate in ruminant production
Improving the efficiency and production of grazing ruminants to support food and fiber production, while reducing the environmental footprint and...
